Clinical Trials Updated in 2025

NCT05666921 | RECRUITING

300 participants

Alexithymia and Attachment Style in Patients With Somatic Symptoms

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-26
Start Date:: 2021-06-15
Completion:: 2026-12-31

Conditions

Somatic Symptom Disorder

Interventions

OTHER

No Results Yet

NCT05663970 | ACTIVE_NOT_RECRUITING | NA

120 participants

Virtual Group Social ABCs - Multi-site Randomized Controlled Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-06-27
Completion:: 2025-04-30

Conditions

Autism Spectrum Disorder
Social Communication Disorder
Autism or Autistic Traits
Autism Spectrum Disorder With Impaired Functional Language
Autism-Related Speech Delay

Interventions

BEHAVIORAL

No Results Yet

NCT05660291 | ACTIVE_NOT_RECRUITING | NA

100 participants

A Study of Time Restricted Eating in Obese Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2023-02-24
Completion:: 2026-09-01

Conditions

Overweight

Interventions

BEHAVIORAL

No Results Yet

NCT05627856 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

4 participants

A Study of GNC-038 Injection in Patients With Relapsed or Refractory NK/ T-cell Lymphoma, AITL, and Other NHL

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2023-02-21
Completion:: 2025-12-31

Conditions

NK/T Cell Lymphoma
Vascular Immunomother T Cell Lymphoma
Non-Hodgkin Lymphoma

Interventions

DRUG

No Results Yet

NCT05576246 | COMPLETED | NA

12 participants

Airway Occlusion Measured During Non-invasive Ventilation to Assess Respiratory Effort

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-10-30
Completion:: 2023-01-01

Conditions

Healthy Volunteers

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05535881 | COMPLETED | NA

400 participants

Strengths to Grow: An Online Parenting Resource

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-10-01
Completion:: 2024-06-28

Conditions

Happiness
Self Efficacy
Positive Affect

Interventions

BEHAVIORAL

No Results Yet

NCT05526066 | TERMINATED | PHASE2

8 participants

Study for Adolescents and Adults With Ornithine Transcarbamylase Deficiency to Evaluate Safety and Tolerability of ARCT-810

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-10-17
Completion:: 2024-10-31

Conditions

Ornithine Transcarbamylase Deficiency
OTC Deficiency
OTCD

Interventions

BIOLOGICAL
OTHER

No Results Yet

NCT05513547 | COMPLETED | NA

51 participants

Beneficial Effects of Daytime Light Exposure and Physical Activity on the Human Circadian Clock and Sleep

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2023-04-27
Completion:: 2025-09-12

Conditions

Circadian System

Interventions

OTHER

No Results Yet

NCT05501769 | COMPLETED | PHASE1

32 participants

ARV-471 in Combination With Everolimus for the Treatment of Advanced or Metastatic ER+, HER2- Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-09-08
Completion:: 2024-07-03

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT05485753 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

7 participants

A Study of GNC-038, a Tetra-specific Antibody, in Patients With Central Nervous System Lymphoma (PCNSL) and Relapsed or Refractory Secondary Central Nervous System Lymphoma (SCNSL)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2023-02-10
Completion:: 2025-12-31

Conditions

Primary Central Nervous System Lymphoma
Secondary Central Nervous System Lymphoma

Interventions

DRUG

No Results Yet

NCT05421728 | ACTIVE_NOT_RECRUITING | NA

516 participants

Effectiveness of Engaging in Advance Care Planning Talks (ENACT) Group Visits in Primary Care for Older Adults With and Without Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-07-26
Completion:: 2027-05-01

Conditions

Advance Care Planning
Primary Health Care

Interventions

BEHAVIORAL

No Results Yet

NCT05393427 | ACTIVE_NOT_RECRUITING | PHASE1

4 participants

A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Urological Tumors and Other Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-02-15
Completion:: 2025-12-31

Conditions

Locally Advanced or Metastatic Urinary Tumors
Other Solid Tumors

Interventions

DRUG

No Results Yet

NCT05385692 | ACTIVE_NOT_RECRUITING | PHASE1

22 participants

A Study of BL-M02D1 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumors or Other Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-06-01
Completion:: 2025-12-31

Conditions

Locally Advanced or Metastatic Digestive Tract Tumors
Solid Tumor

Interventions

DRUG

No Results Yet

NCT05339685 | ACTIVE_NOT_RECRUITING | PHASE1

82 participants

A Study of BL-M02D1 in Patients With Locally Advanced or Metastatic Triple Negative Breast Cancer or Other Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-05-20
Completion:: 2025-12-31

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT05315739 | COMPLETED | NA

75 participants

Vagus Nerve Stimulation for Systemic Lupus Erythematous

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-08-24
Completion:: 2023-08-23

Conditions

Systemic Lupus Erythematosus
Autonomic Dysfunction
Autonomic Neuropathy
Fatigue

Interventions

DEVICE

No Results Yet

NCT05310448 | RECRUITING | NA

10 participants

Tumor Treating Fields for the Treatment of Brainstem Gliomas

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-05-11
Completion:: 2026-09-01

Conditions

Glioma

Interventions

DEVICE

No Results Yet

NCT05271604 | COMPLETED | PHASE2

42 participants

A Phase 2 Open Label Study of BA3021 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-12-13
Completion:: 2025-09-22

Conditions

Head and Neck Cancer
Squamous Cell Carcinoma of Head and Neck
Recurrent Squamous Cell Carcinoma of the Head and Neck
Metastatic Cancer
Metastatic Squamous Cell Carcinoma of the Head and Neck

Interventions

BIOLOGICAL

No Results Yet

NCT05260021 | COMPLETED | PHASE3

99 participants

A Study to Evaluate Tirzepatide (LY3298176) in Pediatric and Adolescent Participants With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin or Basal Insulin or Both

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-04-13
Completion:: 2024-07-30

Conditions

Type2 Diabetes
Diabetes Mellitus
Diabetes Mellitus, Type 2
T2D
T2DM (Type 2 Diabetes Mellitus)
Glucose Metabolism Disorders
Endocrine System Diseases
Metabolic Disease

Interventions

DRUG

Results Available

NCT05245513 | NOT_YET_RECRUITING | NA

145 participants

Enhancing Recovery Capital Amid Opioid Use Disorder Pharmacotherapy: A Pilot Randomized Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2025-12-01
Completion:: 2027-02-28

Conditions

Opioid Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT05238376 | COMPLETED | NA

16 participants

Survivorship Post-HCT Optimization Program

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-12-02
Completion:: 2025-02-26

Conditions

Hematologic Malignancy

Interventions

BEHAVIORAL

No Results Yet

NCT05212233 | COMPLETED

218 participants

Financial Difficulty in Patients With Blood Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-01-27
Completion:: 2024-12-31

Conditions

Chronic Lymphocytic Leukemia
Multiple Myeloma

No Results Yet

NCT05192486 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

12 participants

A Study of GNC-038, a Tetra-specific Antibody, in Participants With R/R Diffuse Large B-cell Lymphoma (DLBCL)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-08-10
Completion:: 2025-12-31

Conditions

Diffuse Large B-cell Lymphoma

Interventions

DRUG

No Results Yet

NCT05177991 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

200 participants

Post-operative Pain Control-TAP Block Using Exparel vs. Marcaine for Hernia Repairs

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-03-01
Completion:: 2024-12-31

Conditions

Inguinal Hernia
Ventral Hernia

Interventions

DRUG

No Results Yet

NCT05160545 | ACTIVE_NOT_RECRUITING | PHASE1

36 participants

A Study of GNC-035, a Tetra-specific Antibody, in Participants With Locally Advanced or Metastatic Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2021-11-26
Completion:: 2025-12-31

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT05143554 | TERMINATED | NA

18 participants

Auricular Neurostimulation for Chemotherapy Induced Nausea and Vomiting

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2021-04-29
Completion:: 2025-09-23

Conditions

Chemotherapy-induced Nausea and Vomiting

Interventions

DEVICE

No Results Yet

NCT05137132 | COMPLETED | NA

70 participants

Unrefined Salmon Oil as Dietary Supplement in Adult Asthmatics

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-04-01
Completion:: 2024-12-09

Conditions

Asthma

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05132231 | ACTIVE_NOT_RECRUITING

394 participants

Canadian Real World Evidence Study of Brodalumab in Plaque Psoriasis to Understand the Impact on Quality of Life and Work Productivity

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-26
Start Date:: 2021-10-22
Completion:: 2025-02-05

Conditions

Psoriasis

Interventions

BIOLOGICAL

No Results Yet

NCT05130294 | WITHDRAWN | NA

0 participants

Unrefined Salmon Oil as Dietary Supplement in Patient With Chronic Obstructive Pulmonary Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2025-07-31
Completion:: 2026-11-30

Conditions

Chronic Obstructive Pulmonary Disease

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05126563 | COMPLETED | PHASE2

79 participants

Randomized Double-Blind Phase 2 Study of Allogeneic HB-adMSCs for the Treatment of Chronic Post-COVID-19 Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-02-02
Completion:: 2024-04-02

Conditions

Post COVID-19 Syndrome

Interventions

BIOLOGICAL
OTHER

Results Available

NCT05116540 | COMPLETED | PHASE2

24 participants

Randomized Double-Blind Phase 2 Efficacy and Safety of Autologous HB-MSCs vs Placebo for Treatment of Multiple Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2021-11-24
Completion:: 2024-06-04

Conditions

Multiple Sclerosis

Interventions

BIOLOGICAL
DRUG

Results Available

NCT05104775 | ACTIVE_NOT_RECRUITING | PHASE1

33 participants

A Study of GNC-035, a Tetra-specific Antibody, in Participants With Relapsed/Refractory Hematologic Malignancy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-02-09
Completion:: 2025-12-31

Conditions

Hematologic Malignancies

Interventions

DRUG

No Results Yet

NCT05095415 | WITHDRAWN | NA

0 participants

Occupational Therapy Pre-operative Education in the Orthopedic Hand Setting

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2021-10-31
Completion:: 2022-04-30

Conditions

Flexor Tendon Rupture
Thumb Osteoarthritis
Distal Radius Fracture

Interventions

OTHER

No Results Yet

NCT05085782 | COMPLETED | PHASE2

48 participants

Reconsolidation Therapy With Propranolol as a Treatment for Chronic Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-02-07
Completion:: 2024-12-30

Conditions

Chronic Low-back Pain
Fibromyalgia

Interventions

DRUG
BEHAVIORAL

No Results Yet

NCT05051462 | COMPLETED | NA

80 participants

Efficacy of Family Constellations in the General Population

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2021-07-19
Completion:: 2022-04-25

Conditions

Mild to Moderate Psychopathological Symptoms

Interventions

BEHAVIORAL

Results Available

NCT05044897 | ACTIVE_NOT_RECRUITING | PHASE2

11 participants

A Clinical Study to Evaluate the Efficacy and Safety of SI-B001 in the Treatment of Recurrent and Metastatic HNSCC

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2021-10-20
Completion:: 2025-12-31

Conditions

Head and Neck Squamous Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT05022654 | ACTIVE_NOT_RECRUITING | PHASE2

22 participants

SI-B001 Combined With Irinotecan in the Treatment of Recurrent Metastatic Esophageal Squamous Cell Carcinoma.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2021-12-13
Completion:: 2025-12-31

Conditions

Esophageal Squamous Cell Carcinomas

Interventions

DRUG

No Results Yet

NCT05020769 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3

14 participants

SI-B001 Combined With Osimertinib Mesylate Tablets in the Treatment of Recurrent Metastatic Non-small Cell Lung Cancer.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2022-01-06
Completion:: 2025-12-31

Conditions

Non-small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT05020457 | ACTIVE_NOT_RECRUITING | PHASE2

69 participants

SI-B001 Combined With Chemotherapy in the Treatment of EGFR/ALK WT Recurrent or Metastatic NSCLC.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2021-12-07
Completion:: 2025-12-31

Conditions

Non Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT05013632 | RECRUITING

2000 participants

COVID-19 International Drug Pregnancy Registry

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-26
Start Date:: 2021-12-01
Completion:: 2027-09-30

Conditions

Covid19

Interventions

DRUG

No Results Yet

NCT04993508 | NOT_YET_RECRUITING | NA

1908 participants

Randomized Prospective Multi Center Cohort Study for Primary Diagnosis of Clinically Significant Prostate Cancer With Combination of PSA/DRE and Multi Parametric Magnetic Resonance Imaging

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-26
Start Date:: 2026-04-01
Completion:: 2030-03-31

Conditions

Prostate Cancer

Interventions

DIAGNOSTIC_TEST
DEVICE
PROCEDURE

No Results Yet