Clinical Trials

NCT04132206 | RECRUITING

60 participants

Longitudinal Characterization of Microbial Signature in Systemic Sclerosis Patients

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-25

Start Date:

2019-10-08

Completion:

2026-06-03

Conditions

• Systemic Sclerosis

Interventions

• OTHER

No Results Yet

NCT04130893 | TERMINATED | NA

10 participants

Response of the Autonomic Nervous System to Auricular Stimulation of the Vagus Nerve (x)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2019-01-17

Completion:

2019-11-21

Conditions

• Vasoconstriction Disorder of Extremities

Interventions

• BEHAVIORAL

No Results Yet

NCT04111809 | TERMINATED

3 participants

Study of 4 Bone Turnover Markers in Patients With Multiple Myeloma Treated With Intravenous Bisphosphonate in Routine Care

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-25

Start Date:

2020-09-29

Completion:

2020-10-20

Conditions

• Multiple Myeloma

Interventions

• BIOLOGICAL

No Results Yet

NCT04110730 | RECRUITING | NA

40 participants

The Influence of 3D Printed Prostheses on Neural Activation Patterns

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2020-01-10

Completion:

2026-08-31

Conditions

• Amniotic Band Syndrome
• Upper Extremity Deformities, Congenital

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT04007562 | WITHDRAWN

0 participants

Acute Rhabdomyolysis and Muscle Pain Associated With Mutations in the LPIN1 Gene - A Retrospective Study Describing the Safety and Efficacy of Hydroxychloroquine Sulfate Given on a Compassionate Basis to Patients Suffering From Lipin-1 Deficiency

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-25

Start Date:

2019-11-04

Completion:

2019-11-04

Conditions

• LIPIN1 Deficiency

Interventions

• DRUG

No Results Yet

NCT04004403 | COMPLETED | NA

80 participants

Alternate Day Fasting, Exercise, and NAFLD

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2019-09-01

Completion:

2024-05-01

Conditions

• Non-Alcoholic Fatty Liver Disease
• Obesity

Interventions

• OTHER

Results Available

NCT03972345 | ENROLLING_BY_INVITATION

750 participants

Influence of Adherence to Growth Hormone Therapy (GHT) With Norditropin® on Near Final Height in Patients With Growth Hormone Deficiency (GHD) and Born Small for Gestational Age (SGA)

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-25

Start Date:

2019-06-21

Completion:

2029-06-30

Conditions

• Growth Hormone Deficiency in Children
• Born Small for Gestational Age

Interventions

• DRUG

No Results Yet

NCT03935997 | ACTIVE_NOT_RECRUITING | NA

594 participants

Implementing, Evaluating, and Scaling Up of the Strengthening a Palliative Approach in Long Term Care (SPA-LTC) Program

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2022-06-01

Completion:

2025-01-31

Conditions

• Frail Elderly Syndrome

Interventions

• OTHER

No Results Yet

NCT03934541 | COMPLETED | PHASE1

24 participants

Evaluating the Safety and Immunogenicity of an HIV-1 gp41 MPER-656 Liposome Vaccine in Healthy, HIV-uninfected Adult Participants

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2019-08-26

Completion:

2021-02-05

Conditions

• HIV Infections

Interventions

• BIOLOGICAL

Results Available

NCT03915691 | ACTIVE_NOT_RECRUITING | NA

201 participants

The RIPPLE AT-PLUS Study

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2022-08-16

Completion:

2026-04-30

Conditions

• Atrial Tachycardia

Interventions

• PROCEDURE

No Results Yet

NCT03915652 | COMPLETED | NA

35 participants

Addressing Disparities in Lupus Care Through an Integrated Care Management Program

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2019-06-21

Completion:

2022-07-20

Conditions

• Systemic Lupus Erythematosus

Interventions

• BEHAVIORAL

Results Available

NCT03869957 | COMPLETED | NA

20 participants

Effect of Parenteral Nutrition With n-3 PUFAs on Patients With Intestinal Failure

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2019-12-01

Completion:

2022-05-01

Conditions

• Intestinal Failure

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT03830775 | WITHDRAWN | NA

0 participants

A Prospective Randomized Double Blinded Controlled Trial of Non-Operative Management of TFCC Injuries

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2020-10-02

Completion:

2022-12-31

Conditions

• Wrist Injuries
• PRP

Interventions

• PROCEDURE

No Results Yet

NCT03784781 | WITHDRAWN

0 participants

Type 2 Innate Lymphoid Cells in Severe Pediatric Asthma

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-25

Start Date:

2016-06-09

Completion:

2020-04-30

Conditions

• Severe Asthma

Interventions

• BIOLOGICAL

No Results Yet

NCT03751566 | RECRUITING | NA

60 participants

Acupuncture as the Therapeutic Modalities of Acute Toxicity in the Radiotherapy of Head and Neck Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2021-10-05

Completion:

2023-09-04

Conditions

• Malignant Tumor of Soft Tissue of Head, Face and Neck

Interventions

• OTHER
• DRUG

No Results Yet

NCT03740841 | TERMINATED | NA

15 participants

Evaluation of the Effects of LUNII on Pre-operative Anxiety and on the Post-operative Period in Children With Cleft Lip and Palate Admitted for Alveolar Bone Graft: Pilot Study

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2019-01-08

Completion:

2019-01-08

Conditions

• Cleft Lip and Palate

Interventions

• BEHAVIORAL

No Results Yet

NCT03692455 | ENROLLING_BY_INVITATION

75 participants

Effect of Laparoscopic Sleeve Gastrectomy Versus Roux-en-Y Gastric Bypass on Gastroesophageal Reflux Disease: An 8-Year Prospective Cohort Study

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-25

Start Date:

2025-09-17

Completion:

2025-10-17

Conditions

• Gastroesophageal Reflux Disease
• Morbid Obesity

No Results Yet

NCT03690388 | ACTIVE_NOT_RECRUITING | PHASE3

187 participants

A Study of Cabozantinib Compared With Placebo in Subjects With Radioiodine-refractory Differentiated Thyroid Cancer Who Have Progressed After Prior Vascular Endothelial Growth Factor Receptor (VEGFR) -Targeted Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2018-10-05

Completion:

2020-08-19

Conditions

• Differentiated Thyroid Cancer

Interventions

• DRUG

Results Available

NCT03522025 | ACTIVE_NOT_RECRUITING | NA

70 participants

GMK-UNI Anatomical UKA: Fixation of Cemented vs Cementless Designs

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2019-02-15

Completion:

2026-12-01

Conditions

• Osteoarthritis, Knee

Interventions

• DEVICE

No Results Yet

NCT03404024 | WITHDRAWN | PHASE2

0 participants

Safety and Efficacy Study of Gene Therapy for Acute Myocardial Infarction in Korea

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2018-01-25

Completion:

2019-08-20

Conditions

• Ischemic Heart Disease
• Acute Myocardial Infarction

Interventions

• BIOLOGICAL
• DRUG
• DEVICE

No Results Yet

NCT03367572 | COMPLETED | PHASE3

1363 participants

Treatment of Refractory Nausea and Vomiting in Patients With Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2018-04-19

Completion:

2024-04-13

Conditions

• Breast Carcinoma

Interventions

• DRUG
• OTHER

Results Available

NCT03346954 | COMPLETED | NA

33 participants

Impact of [11C]-Methionine PET/MRI in the Detection of Pituitary Adenomas Secreting ACTH and Causing Cushing's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2017-12-11

Completion:

2019-06-11

Conditions

• Cushing's Disease

Interventions

• OTHER

No Results Yet

NCT03282916 | COMPLETED | PHASE2

120 participants

Anti-viral Therapy in Alzheimer's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2018-02-12

Completion:

2024-09-05

Conditions

• Alzheimer Disease
• Herpes Simplex 1
• Herpes Simplex 2

Interventions

• DRUG

Results Available

NCT03267615 | RECRUITING

10000 participants

VICIS - Vienna Cirrhosis Study

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-25

Start Date:

2017-02-01

Completion:

2026-12-31

Conditions

• Liver Cirrhosis
• Portal Hypertension
• Ascites
• Variceal Hemorrhage
• Hepatic Encephalopathy

No Results Yet

NCT03244072 | NOT_YET_RECRUITING | PHASE2/PHASE3

60000 participants

Safety and Efficacy of Intracameral Zimoxin for Prevention of Endophthalmitis After Cataract Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2026-06-01

Completion:

2030-10-31

Conditions

• Endophthalmitis

Interventions

• DRUG

No Results Yet

NCT03211663 | ACTIVE_NOT_RECRUITING

269 participants

Performance of MOTO Medial® Unicompartmental Knee Arthroplasty

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-25

Start Date:

2017-10-09

Completion:

2025-12-01

Conditions

• Knee Osteoarthritis
• Knee Arthritis
• Knee Pain Chronic

Interventions

• DEVICE

No Results Yet

NCT03191682 | ACTIVE_NOT_RECRUITING | PHASE1

38 participants

A First-in-Human Study of PRL3-ZUMAB

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2017-02-20

Completion:

2027-02-20

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT03184571 | COMPLETED | PHASE2

99 participants

Bemcentinib (BGB324) in Combination With Pembrolizumab in Patients With Advanced Non-small Cell Lung Cancer (NSCLC)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2017-10-02

Completion:

2022-10-27

Conditions

• Lung Cancer Metastatic
• NSCLC Stage IV
• Adenocarcinoma of Lung

Interventions

• DRUG

Results Available

NCT03130777 | ACTIVE_NOT_RECRUITING | NA

86 participants

ALTERRA: SAPIEN 3 THV With the Alterra Adaptive Prestent

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2017-08-22

Completion:

2022-07-14

Conditions

• Pulmonary Disease
• Transcatheter Pulmonary Valve Replacement (TPVR)
• Tetralogy of Fallot
• Congenital Heart Disease
• Pulmonary Regurgitation

Interventions

• DEVICE

Results Available

NCT03091374 | COMPLETED | PHASE2

22 participants

Impact of Recombinant Human Growth Hormone on HIV Persistence

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2016-12-31

Completion:

2021-03-31

Conditions

• Human Immunodeficiency Virus
• Growth Hormone Treatment

Interventions

• DRUG

No Results Yet

NCT03071692 | TERMINATED | PHASE3

10544 participants

Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2017-03-23

Completion:

2022-07-27

Conditions

• Type2 Diabetes
• Dyslipidemia

Interventions

• DRUG

Results Available

NCT03056170 | COMPLETED | NA

37 participants

Neurophysiological Impact of a Fronto-temporal tDCS Stimulation in Healthy Subjects: a Multimodal Imaging Approach

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2015-11-13

Completion:

2017-04-19

Conditions

• Healthy

Interventions

• DEVICE

No Results Yet

NCT03041311 | COMPLETED | PHASE2

107 participants

Carboplatin, Etoposide, and Atezolizumab With or Without Trilaciclib (G1T28), a CDK4/6 Inhibitor, in Extensive-Stage SCLC

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2017-06-29

Completion:

2018-08-17

Conditions

• Small Cell Lung Cancer

Interventions

• DRUG

Results Available

NCT02750397 | COMPLETED

13 participants

HIV-to-HIV Transplant at MGH

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-25

Start Date:

2016-08-31

Completion:

2025-07-15

Conditions

• HIV
• Awaiting Organ Transplant

No Results Yet

NCT02731638 | COMPLETED | PHASE3

70 participants

Mycotic Antimicrobial Localized Injection for Treatment of Corneal Ulcers

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2016-09-30

Completion:

2018-07-31

Conditions

• Corneal Ulcer
• Fungal Keratitis

Interventions

• DRUG

Results Available

NCT02673775 | COMPLETED | NA

135 participants

Air Pollution Study: The Effect of Ozone on the Lung

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2016-02-29

Completion:

2022-06-07

Conditions

• Air Pollution

Interventions

• OTHER

Results Available

NCT02668510 | WITHDRAWN | NA

0 participants

RCT Comparing ESWT With PRP for Plantar Fasciitis in High Demand Cohort

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2016-01-31

Completion:

2023-12-11

Conditions

• Fasciitis, Plantar

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT02630628 | COMPLETED | PHASE3

130 participants

Efficacy and Safety of Tacrolimus Versus Mycophenolate in Lupus Nephritis

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2015-12-05

Completion:

2024-12-27

Conditions

• Lupus Nephritis

Interventions

• DRUG

No Results Yet

NCT02562118 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

40 participants

Neoadjuvant Lenvatinib Combined With Letrozole in Hormone Receptor Positive Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-25

Start Date:

2015-10-02

Completion:

2027-01-31

Conditions

• Breast Cancer

Interventions

• DRUG

No Results Yet

NCT02557438 | ACTIVE_NOT_RECRUITING

240 participants

Effects of Weight Loss Surgery on Bone Health in Adolescents

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-25

Start Date:

2015-06-01

Completion:

2026-12-31

Conditions

• Obesity
• Surgery

Interventions

• PROCEDURE

No Results Yet