Clinical Trials Updated in 2025

NCT07190716 | NOT_YET_RECRUITING | PHASE1

36 participants

A Study to Evaluate the Safety of GR2301 Injection in Healthy Volunteers.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-10-10
Completion:: 2026-05-30

Conditions

Single Ascending Dose
Healthy Subjects

Interventions

BIOLOGICAL

No Results Yet

NCT07190703 | NOT_YET_RECRUITING

200 participants

Research on Early Diagnosis and Risk Stratification Biomarkers of Anti-Tumor Drug-Associated Interstitial Pneumonia Driven by Multi-Omics Integration

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-09-30
Completion:: 2026-09-30

Conditions

Anti-Tumor Drug-Associated Interstitial Pneumonia

No Results Yet

NCT07190677 | RECRUITING

300 participants

First-line Therapy With Nivolumab Plus Ipilimumab in Combination With Chemotherapy for Metatastatic NSCLC (NICReWo Trial)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-01-17
Completion:: 2025-12-31

Conditions

Non Small Cell Lung Cancer Metastatic

No Results Yet

NCT07190664 | NOT_YET_RECRUITING | NA

228 participants

A Prospective, Randomized, Double-blind Study on the Effects of Different Anesthesia Strategies on Postoperative Cough in Patients Undergoing Video-assisted Thoracoscopic Surgery.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-10-01
Completion:: 2025-12-01

Conditions

Chronic Cough
Video-assisted Thoracoscopic Surgery (VATS)

Interventions

OTHER

No Results Yet

NCT07190651 | NOT_YET_RECRUITING

50 participants

Development of a New Remote Monitoring Model for Patients With HR+HER2- Breast Cancer in Treatment With CDK4/6 Inhibitors and Hormone Therapy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-10-01
Completion:: 2026-09-30

Conditions

Breast Cancer
CDK4/6 Inhibitor

Interventions

OTHER

No Results Yet

NCT07190638 | RECRUITING | NA

80 participants

Comparison of Outcomes and Surgical Time Between Cortical and Medullary Suture vs. Medullary-Only Suture: Cortex Clinical Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-07-23
Completion:: 2027-03-31

Conditions

RCC, Renal Cell Cancer

Interventions

PROCEDURE
DEVICE

No Results Yet

NCT07190573 | RECRUITING

350 participants

Head and Neck Cancer Omics/Integrated Precision Medicine (HOPE)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-04-25
Completion:: 2030-01-31

Conditions

Head and Neck Cancer

No Results Yet

NCT07190521 | NOT_YET_RECRUITING | NA

111 participants

Hypnobreastfeeding vs. Traditional Education

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-09-25
Completion:: 2025-11-15

Conditions

Breastfeeding

Interventions

OTHER

No Results Yet

NCT07190417 | COMPLETED | NA

120 participants

Evaluation of Physiological Effects Induced by Low Level Light Irradiation on the Acupoints of the Hand

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-24
Start Date:: 2021-03-05
Completion:: 2021-05-04

Conditions

Insomnia
Anxiety
Acupuncture
Low-level Laser Therapy

Interventions

OTHER

No Results Yet

NCT07190391 | NOT_YET_RECRUITING

425 participants

Phase 4 Multicenter, Open-label Study on Efficacy and Safety of Apremilast in Moderate-to-severe Psoriasis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-09-30
Completion:: 2026-12-31

Conditions

Psoriasis

No Results Yet

NCT07190274 | NOT_YET_RECRUITING

645 participants

Prospective Observational Cohort Study on Impact of Frailty on Risk Prediction, Treatment Strategies, and Short-Term Outcomes in Patients With Acute Coronary Syndrome

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-12-01
Completion:: 2027-12-01

Conditions

Frailty
ACS (Acute Coronary Syndrome)
MACE
GRACE Score

No Results Yet

NCT07190261 | NOT_YET_RECRUITING | PHASE2

3 participants

A Single-arm Phase 2 Prospective Clinical Study of Enatumab in the Treatment of Relapsed/Refractory Warm Antibody Autoimmune Hemolytic Anemia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-09-18
Completion:: 2027-09-18

Conditions

Autoimmune Hemolytic Anemia

Interventions

DRUG

No Results Yet

NCT07190183 | RECRUITING

100 participants

Washed Microbiota Transplantation for Food Intolerance

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-01-01
Completion:: 2035-02-10

Conditions

Food Intolerance

Interventions

PROCEDURE

No Results Yet

NCT07190144 | COMPLETED

122 participants

Coronary Flow Reserve Changes After Semaglutide Treatment

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-01-07
Completion:: 2025-08-01

Conditions

The Study Focused on the Vascular Effects of Semaglutide in Both Diabetic and Non-diabetic Patients
Obesity &Amp; Overweight

No Results Yet

NCT07190118 | NOT_YET_RECRUITING

20 participants

Effects of Emicizumab Treatment in Patients With Hemophilia A

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-09-30
Completion:: 2025-11-10

Conditions

Hemophilia A
Musculoskeletal Assessment
Musculoskeletal Abnormalities

No Results Yet

NCT07190092 | RECRUITING | NA

12 participants

Deep Anterior Cerebellar Stimulation in Treatment of Poststroke Spasticity and Motor Function Impairment.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-24
Start Date:: 2024-09-01
Completion:: 2027-12-30

Conditions

Post Stroke Spasticity
Dystonia

Interventions

PROCEDURE

No Results Yet

NCT07190053 | NOT_YET_RECRUITING

100 participants

Long Term Treatment Strategies and Effectiveness of Secukinumab in Patient With JIA Subtypes of JPsA and ERA: Study From German BIKER Registry.

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-12-31
Completion:: 2029-09-18

Conditions

Enthesitis-related Arthritis (ERA)
Juvenile Psoriatic Arthritis (JPsA)

Interventions

OTHER

No Results Yet

NCT07190040 | COMPLETED

179 participants

Integrating Multi-Omics Data for Enhanced Prognosis Prediction in Gastric Cancer Post-Neoadjuvant Therapy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-24
Start Date:: 2019-01-01
Completion:: 2022-12-31

Conditions

Gastric Cancer (GC)

No Results Yet

NCT07190027 | NOT_YET_RECRUITING | PHASE1/PHASE2

246 participants

Immunodynamics-Guided Optimization of Individualized Immunochemotherapy in Advanced Driver-Negative NSCLC: A Randomized Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-11-30
Completion:: 2025-11-30

Conditions

Advanced Non-Small Cell Lung Cancer (NSCLC)

Interventions

DRUG

No Results Yet

NCT07190001 | NOT_YET_RECRUITING | EARLY_PHASE1

18 participants

YOLT-204 in Patients With Hemoglobinopathies

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-09-30
Completion:: 2027-04-30

Conditions

Hemoglobinopathies (Transfusion-dependent β-thalassemia and Sickle Cell Disease)

Interventions

DRUG

No Results Yet

NCT07189988 | ACTIVE_NOT_RECRUITING

20 participants

Observational Pilot Study to Explore the Social and Health Impacts of a New Model of Care in Oregon: Psilocybin Services on Alcoholism

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-03-05
Completion:: 2026-06-10

Conditions

Alcohol Use Disorder

Interventions

OTHER

No Results Yet

NCT07189975 | COMPLETED | NA

45 participants

Eccentric Cycling : a Promising Training Modality for Sedentary People

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-24
Start Date:: 2024-04-20
Completion:: 2025-01-15

Conditions

Sedentary
Deconditioning
Eccentric Exercise Training
Eccentric Cycling Exercise
Elderly
Healthy Participants

Interventions

OTHER

No Results Yet

NCT07189962 | COMPLETED | PHASE1

20 participants

A Pharmacokinetic Study of SHR8554 Injection in the Population With Renal Insufficiency and Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-24
Start Date:: 2022-09-20
Completion:: 2023-04-13

Conditions

Moderate to Severe Postoperative Pain

Interventions

DRUG

No Results Yet

NCT07189910 | NOT_YET_RECRUITING | PHASE4

150 participants

Sequential rhTPO and Eltrombopag Following Glucocorticoids for Severe Adult ITP

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-12-01
Completion:: 2027-11-01

Conditions

Primary Immune Thrombocytopenia (ITP)

Interventions

DRUG
OTHER

No Results Yet

NCT07189884 | NOT_YET_RECRUITING | PHASE1/PHASE2

33 participants

Pyrotinib Maleate Tablets in Combination With Dalpiciclib Isethionate Tablets and Standard Endocrine Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-09-23
Completion:: 2026-06-30

Conditions

Locally Advanced Breast Cancer (LABC)

Interventions

DRUG

No Results Yet

NCT07189806 | RECRUITING

250 participants

Longitudinal Phenotyping and Endotyping Study in Adult Patients With Mild, Moderate, or Severe Asthma

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-08-08
Completion:: 2050-08-08

Conditions

Asthma (Diagnosis)

No Results Yet

NCT07189780 | NOT_YET_RECRUITING | NA

200 participants

Comparison of Different Surgical Approaches in Female Rectal Cancer.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-10-01
Completion:: 2027-08-31

Conditions

Rectal Cancer Surgery

Interventions

PROCEDURE

No Results Yet

NCT07189754 | COMPLETED | NA

70 participants

A Study of Sabroxy™ (Oroxylum Indicum Extract) for Improving Cognitive Function in Adults With Mild Memory Concerns

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-24
Start Date:: 2020-11-02
Completion:: 2021-02-08

Conditions

Mild Cognitive Impairment (MCI)
Cognitive Dysfunction, Cognitive Disorder
Memory Problems

Interventions

DIETARY_SUPPLEMENT
OTHER

No Results Yet

NCT07189741 | NOT_YET_RECRUITING

50 participants

Dynamic Breath VOC Profiling as a Non-invasive Tool to Assess Hemodialysis Adequacy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-09-30
Completion:: 2026-01-01

Conditions

Uremia
Uremia; Chronic
Hemodialysis

Interventions

PROCEDURE

No Results Yet

NCT07189728 | NOT_YET_RECRUITING

1500 participants

The MagnaSafe-2 Registry: Assessing the Risks of Magnetic Resonance Imaging in Three Patient Groups

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-24
Start Date:: 2026-01-01
Completion:: 2031-01-01

Conditions

Pacemakers
MRI Imaging
Implantable Cardioverter Defibrillator (ICD)

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT07189715 | RECRUITING | NA

80 participants

Optimization of Imagery Rescripting Research Using Generative Artificial Intelligence

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-06-01
Completion:: 2025-11-30

Conditions

Generalized Anxiety
Fear of Failure
Rumination

Interventions

BEHAVIORAL

No Results Yet

NCT07189663 | NOT_YET_RECRUITING

1468 participants

Study on the Correlation Between Serum and Fecal Sialic Acid Levels and Tumor Characteristics as Well as Postoperative Anastomotic Leakage in Patients With Colorectal Tumors

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-09-25
Completion:: 2026-09-10

Conditions

Colorectal Neoplasia
Anastomotic Leakage

No Results Yet

NCT07189650 | NOT_YET_RECRUITING

30 participants

Pilot Study for Collecting Data on Liver Adipose Content in Adults by Ultrasound Attenuation and Scattering Imaging and MRI Proton-density

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-09-30
Completion:: 2026-03-31

Conditions

Metabolic Dysfunction-Associated Liver Disease

Interventions

DEVICE

No Results Yet

NCT07189637 | NOT_YET_RECRUITING | NA

48 participants

The Combined Effect of the Mediterranean Diet and Intermittent Fasting on Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-11-01
Completion:: 2026-07-01

Conditions

Hypertension

Interventions

OTHER

No Results Yet

NCT07189611 | NOT_YET_RECRUITING | NA

600 participants

Implementation of a Blended Online and Offline Teaching Model

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-24
Start Date:: 2026-01-01
Completion:: 2028-01-01

Conditions

Generative Artificial Intelligence

Interventions

BEHAVIORAL

No Results Yet

NCT07189533 | NOT_YET_RECRUITING | NA

80 participants

SENior PRIorat: Participatory Research for the Improvement of Lifestyles, Quality of Life, Emotional Well-being, and Locomotor Abilities of Older Adults in the Priorat

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-10-06
Completion:: 2026-12-30

Conditions

Healthy Lifestyle

Interventions

BEHAVIORAL

No Results Yet

NCT07189520 | NOT_YET_RECRUITING

700 participants

1. SAFE-AI ONCO-TRACK: Multimodal GenAI for Early Detection of Minimal Residual Disease and Recurrence in Gastrointestinal Oncology

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-24
Start Date:: 2026-06-01
Completion:: 2028-06-01

Conditions

Rectal Cancer

Interventions

OTHER

No Results Yet

NCT07189494 | RECRUITING

1000 participants

European Newborn Study: Early Markers for a Better LifE

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-24
Start Date:: 2023-10-06
Completion:: 2029-01-01

Conditions

Cerebral Palsy

No Results Yet

NCT07189481 | COMPLETED

151 participants

Design and Evaluation of a Team Timeout Checklist (TTOC) to Improve Information Exchange in the Operating Room Before Skin Incision

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-24
Start Date:: 2024-08-01
Completion:: 2025-05-31

Conditions

Checklist
Teamwork
Information Exchange

No Results Yet

NCT07189468 | NOT_YET_RECRUITING

100 participants

AI-based Progression and Medication Response Prediction Study in Parkinson's Disease

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-24
Start Date:: 2025-10-06
Completion:: 2027-04-01

Conditions

PARKINSON DISEASE (Disorder)

Interventions

DEVICE

No Results Yet