Clinical Trials

NCT05004311 | COMPLETED | PHASE1

16 participants

The Effect of Severe Kidney Impairment on Cenerimod Pharmacokinetics

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2021-09-27

Completion:

2023-07-27

Conditions

• Healthy
• Renal Impairment

Interventions

• DRUG

No Results Yet

NCT05002933 | COMPLETED | PHASE4

570 participants

A Clinical Efficacy and Safety Study of Insulin Glargine U300 in Chinese Adult Patients With Uncontrolled Type 2 Diabetes Mellitus With a 3-month Extension Period

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2021-05-20

Completion:

2023-02-24

Conditions

• Type 2 Diabetes Mellitus

Interventions

• DRUG

No Results Yet

NCT04980027 | COMPLETED | PHASE4

228 participants

Evaluation of the Safety and Efficacy of Insulin Glargine 300 U/ml (Gla-300) in Insulin-naïve Patients With Type 2 Diabetes Mellitus Uncontrolled on Oral Antihyperglycemic Drugs

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2021-06-07

Completion:

2022-12-23

Conditions

• Type 2 Diabetes Mellitus

Interventions

• DRUG

No Results Yet

NCT04979000 | COMPLETED

49 participants

HPV in Sinonasal Ca: Retrospective Analysis Association of Human Papilloma Virus (HPV) Serology and Behavioral Risk Factors

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-22

Start Date:

2021-08-03

Completion:

2025-05-28

Conditions

• Sinonasal Carcinoma
• HPV-Related Squamous Cell Carcinoma

No Results Yet

NCT04953637 | ACTIVE_NOT_RECRUITING | NA

60 participants

Physiotherapy and Deep Brain Stimulation in Parkinson's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2021-04-15

Completion:

2025-11-30

Conditions

• Parkinson Disease

Interventions

• OTHER

No Results Yet

NCT04945018 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

10 participants

A Study of iPS Cell-derived Cardiomyocyte Spheroids (HS-001) in Patients With Heart Failure (LAPiS Study)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2022-04-19

Completion:

2025-07-31

Conditions

• Heart Failure
• Ischemic Heart Disease

Interventions

• BIOLOGICAL
• DEVICE

No Results Yet

NCT04942093 | RECRUITING | NA

200 participants

NUTritional Impact of a Hypocaloric Hyperprotein Diet Before Obesity Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2023-10-09

Completion:

2026-11-20

Conditions

• Diet, Healthy
• Obesity, Visceral
• Bariatric Surgery Candidate

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT04936854 | RECRUITING | PHASE2

60 participants

Sirolimus vs Corticosteroids in Treatment of Thyroid Eye Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2023-01-01

Completion:

2028-01-31

Conditions

• Thyroid-Associated Ophthalmopathy

Interventions

• DRUG

No Results Yet

NCT04858217 | RECRUITING

270 participants

Periprosthetic Joint Infections: Diagnostic Accuracy and Cost-effectiveness Analysis of Serum and Synovial Markers

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-22

Start Date:

2022-02-01

Completion:

2025-06-17

Conditions

• Prosthetic Joint Infection

No Results Yet

NCT04856930 | COMPLETED | PHASE2

149 participants

A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Participants With Hidradenitis Suppurativa

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2021-07-07

Completion:

2022-07-15

Conditions

• Hidradenitis Suppurativa

Interventions

• BIOLOGICAL

Results Available

NCT04856917 | COMPLETED | PHASE2

123 participants

A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Participants With Acne Vulgaris

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2021-05-15

Completion:

2022-02-01

Conditions

• Acne Vulgaris

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT04846829 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

30 participants

Effects of Intravenous (IV) Citalopram Hydrochloride During Transcranial Magnetic Stimulation in Major Depressive Disorder (MDD)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2017-04-24

Completion:

2028-04-24

Conditions

• Major Depressive Disorder

Interventions

• DRUG
• DEVICE

No Results Yet

NCT04844190 | WITHDRAWN | NA

0 participants

Use of EndoFLIP and Manometry Prior to G-POEM

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2021-09-15

Completion:

2024-03-01

Conditions

• Gastroparesis

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04819893 | RECRUITING

135 participants

Study of the Involvement of Fatty Acids in Retinopathy of Prematurity: Relationship Between Retinopathy of Prematurity and the Rate of Expression of Transplacental Fatty Acid Receptors.

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-22

Start Date:

2021-04-20

Completion:

2027-02-28

Conditions

• Prematurity
• Retinopathy

Interventions

• BIOLOGICAL
• OTHER

No Results Yet

NCT04819464 | COMPLETED | PHASE1

24 participants

A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics of a Single Dose of Cenerimod

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2021-08-25

Completion:

2024-08-18

Conditions

• Healthy
• Hepatic Impairment

Interventions

• DRUG

No Results Yet

NCT04812470 | COMPLETED | PHASE1

8 participants

Hepatic Arterial Infusion of Autologous Tumor Infiltrating Lymphocytes in Patients With Melanoma and Liver Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2023-02-06

Completion:

2025-05-26

Conditions

• Metastatic Uveal Melanoma
• Metastatic Cutaneous Melanoma

Interventions

• DRUG

No Results Yet

NCT04808245 | ACTIVE_NOT_RECRUITING | PHASE1

15 participants

A MultIceNTER Phase I Peptide VaCcine Trial for the Treatment of H3-Mutated Gliomas

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2023-02-15

Completion:

2026-11-30

Conditions

• Newly Diagnosed H3-mutated Glioma

Interventions

• DRUG
• BIOLOGICAL
• OTHER

No Results Yet

NCT04795973 | COMPLETED | NA

80 participants

Effects of Intermittent Fasting on Fatty Liver Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2020-09-22

Completion:

2021-04-30

Conditions

• Sensitivity to Thyroid Hormones
• Metabolic Parameters
• in Patients With FLD

Interventions

• BEHAVIORAL

No Results Yet

NCT04787627 | COMPLETED | NA

17 participants

Clinical Investigation (Beta) of Power Knee Mainstream - Dynamic

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2019-11-18

Completion:

2020-07-06

Conditions

• Prosthesis User
• Amputation

Interventions

• DEVICE

Results Available

NCT04772456 | RECRUITING | PHASE1

5 participants

Hyperpolarized 13C-pyruvate Metabolic MRI With Infiltrating Gliomas

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2020-08-11

Completion:

2026-08-31

Conditions

• Glioma

Interventions

• DRUG

No Results Yet

NCT04770766 | COMPLETED

840 participants

Non-medical Practitioner Workforce in the Urgent and Emergency Care System Skill-mix in England

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-22

Start Date:

2021-03-01

Completion:

2025-03-31

Conditions

• Emergencies

Interventions

• OTHER

No Results Yet

NCT04762017 | COMPLETED | PHASE2

36 participants

OCS-05 in Patients With Optic Neuritis

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2021-02-10

Completion:

2024-09-16

Conditions

• Optic Neuritis

Interventions

• DRUG
• OTHER

No Results Yet

NCT04759703 | TERMINATED | PHASE2/PHASE3

75 participants

Treatment of Restless Legs Symptoms With Pramipexole to Improve the Outcomes of Protracted Opioid Withdrawal in OUD

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2022-01-24

Completion:

2024-05-24

Conditions

• Sleep Disorder
• Restless Legs Syndrome
• Opioid-use Disorder
• Opioid Withdrawal

Interventions

• DRUG

Results Available

NCT04754906 | RECRUITING

684 participants

Analysis of Motor Skills in Subjects Aged 55 and Over: the Role of Cognitive Abilities for Planning Movement.

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-22

Start Date:

2021-01-25

Completion:

2028-12-31

Conditions

• Mild Cognitive Disorder

Interventions

• OTHER

No Results Yet

NCT04724941 | RECRUITING

2000 participants

Prodromal Alpha-Synuclein Screening in Parkinson's Disease Study

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-22

Start Date:

2021-06-01

Completion:

2027-12-31

Conditions

• Parkinson Disease

Interventions

• OTHER

No Results Yet

NCT04710758 | RECRUITING | NA

1018 participants

Multicenter Study on Laparoscopic Total Gastrectomy for Advanced Gastric Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2021-01-20

Completion:

2028-12-31

Conditions

• Stomach Neoplasms

Interventions

• PROCEDURE

No Results Yet

NCT04697069 | TERMINATED | PHASE2

4 participants

A Study to Evaluate of the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Acneiform Rash

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2021-05-04

Completion:

2021-12-13

Conditions

• Acneiform Eruptions

Interventions

• BIOLOGICAL

Results Available

NCT04678362 | RECRUITING | PHASE2

50 participants

TALazoparib and Avelumab as Maintenance Therapy in Platinum-Sensitive Metastatic or Locally Advanced URothelial Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2021-06-01

Completion:

2023-07-28

Conditions

• Urothelial Carcinoma

Interventions

• DRUG

No Results Yet

NCT04669041 | COMPLETED | PHASE3

305 participants

A Study to Evaluate the Efficacy and the Safety of Single Pill Combination (SPC) Ezetimibe/Rosuvastatin in Chinese Adult Patients With Primary Hypercholesterolemia Not Adequately Controlled on Statin Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2020-12-08

Completion:

2022-06-15

Conditions

• Hypercholesterolemia

Interventions

• DRUG

No Results Yet

NCT04667000 | COMPLETED | NA

35 participants

The Effect of Forced Air Warming During Caseraen Section on Maternal Hypothermia: Randomized Controlled Trial

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2021-05-01

Completion:

2022-09-30

Conditions

• Cesarean Section Complications
• Hypothermia

Interventions

• OTHER

No Results Yet

NCT04666311 | COMPLETED

1400 participants

Diagnostic Accuracy of CAD4TB and C-reactive Protein Assay as Triage Tests for Pulmonary Tuberculosis

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-22

Start Date:

2021-02-15

Completion:

2022-04-05

Conditions

• Pulmonary Tuberculosis
• Tuberculosis Diagnosis
• Covid-19
• HIV

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04648449 | ACTIVE_NOT_RECRUITING

1000 participants

Artificial Intelligence (AI) Support in Medical Emergency Calls

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-22

Start Date:

2020-09-01

Completion:

2026-08-31

Conditions

• Stroke, Acute
• Apoplexy; Brain
• Emergencies
• Communication, Multidisciplinary

Interventions

• OTHER

No Results Yet

NCT04625049 | ENROLLING_BY_INVITATION

100 participants

Does Microglial Activation Promote Lesion Growth and Progression Among Multiple Sclerosis Patients

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-22

Start Date:

2021-04-01

Completion:

2030-11-30

Conditions

• Multiple Sclerosis

No Results Yet

NCT04614480 | RECRUITING | PHASE2

7976 participants

Exome Analysis (Complexe vs Simple) to Help the Therapeutic Decision for the Precision Medicine

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2020-08-25

Completion:

2028-09-02

Conditions

• Cancer

Interventions

• GENETIC

No Results Yet

NCT04569409 | COMPLETED | PHASE3

104 participants

Clinical Study to Evaluate Efficacy and Safety of ALLO-ASC-DFU in Patients With Diabetic Wagner Grade 2 Foot Ulcers.

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2020-07-14

Completion:

2024-12-05

Conditions

• Diabetic Foot Ulcer

Interventions

• BIOLOGICAL
• PROCEDURE

No Results Yet

NCT04541537 | COMPLETED | NA

35 participants

Isolation of Volatile Organic Compounds (VOCs) Related to the Olfactory Signature of Breast Cancer. (KDOGCOV)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2021-01-25

Completion:

2021-12-09

Conditions

• Breast Cancer
• Surgery

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04521738 | COMPLETED | PHASE1

48 participants

First-in-human Study to Assess Safety and Tolerability of a Single Subcutaneous Dose of SAR441255 in Lean to Overweight Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2019-04-25

Completion:

2019-09-26

Conditions

• Overweight
• Healthy Subjects

Interventions

• DRUG

No Results Yet

NCT04519164 | COMPLETED | PHASE4

79 participants

Aldosterone, the Mineralocorticoid Receptor, and Cardiovascular Disease in Obesity

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2020-12-01

Completion:

2025-09-17

Conditions

• Metabolic Syndrome
• Hypertension
• Overweight and Obesity

Interventions

• DRUG

No Results Yet

NCT04487067 | COMPLETED | PHASE3

152 participants

A Study of Atezolizumab (Tecentriq) in Combination With Bevacizumab to Investigate Safety and Efficacy in Patients With Unresectable Hepatocellular Carcinoma Not Previously Treated With Systemic Therapy-Amethista

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2020-08-25

Completion:

2024-08-13

Conditions

• Carcinoma, Hepatocellular

Interventions

• DRUG

Results Available

NCT04450251 | COMPLETED

173 participants

Testing a Wearable Monitor for Fetal Heart Rate Estimation, Fetal Movement and Uterine Activity Detection

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-22

Start Date:

2018-08-29

Completion:

2020-05-10

Conditions

• Pregnancy

Interventions

• OTHER

No Results Yet