Clinical Trials

NCT04770766 | COMPLETED

840 participants

Non-medical Practitioner Workforce in the Urgent and Emergency Care System Skill-mix in England

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-22

Start Date:

2021-03-01

Completion:

2025-03-31

Conditions

• Emergencies

Interventions

• OTHER

No Results Yet

NCT04762017 | COMPLETED | PHASE2

36 participants

OCS-05 in Patients With Optic Neuritis

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2021-02-10

Completion:

2024-09-16

Conditions

• Optic Neuritis

Interventions

• DRUG
• OTHER

No Results Yet

NCT04759703 | TERMINATED | PHASE2/PHASE3

75 participants

Treatment of Restless Legs Symptoms With Pramipexole to Improve the Outcomes of Protracted Opioid Withdrawal in OUD

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2022-01-24

Completion:

2024-05-24

Conditions

• Sleep Disorder
• Restless Legs Syndrome
• Opioid-use Disorder
• Opioid Withdrawal

Interventions

• DRUG

Results Available

NCT04754906 | RECRUITING

684 participants

Analysis of Motor Skills in Subjects Aged 55 and Over: the Role of Cognitive Abilities for Planning Movement.

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-22

Start Date:

2021-01-25

Completion:

2028-12-31

Conditions

• Mild Cognitive Disorder

Interventions

• OTHER

No Results Yet

NCT04724941 | RECRUITING

2000 participants

Prodromal Alpha-Synuclein Screening in Parkinson's Disease Study

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-22

Start Date:

2021-06-01

Completion:

2027-12-31

Conditions

• Parkinson Disease

Interventions

• OTHER

No Results Yet

NCT04710758 | RECRUITING | NA

1018 participants

Multicenter Study on Laparoscopic Total Gastrectomy for Advanced Gastric Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2021-01-20

Completion:

2028-12-31

Conditions

• Stomach Neoplasms

Interventions

• PROCEDURE

No Results Yet

NCT04697069 | TERMINATED | PHASE2

4 participants

A Study to Evaluate of the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Acneiform Rash

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2021-05-04

Completion:

2021-12-13

Conditions

• Acneiform Eruptions

Interventions

• BIOLOGICAL

Results Available

NCT04678362 | RECRUITING | PHASE2

50 participants

TALazoparib and Avelumab as Maintenance Therapy in Platinum-Sensitive Metastatic or Locally Advanced URothelial Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2021-06-01

Completion:

2023-07-28

Conditions

• Urothelial Carcinoma

Interventions

• DRUG

No Results Yet

NCT04669041 | COMPLETED | PHASE3

305 participants

A Study to Evaluate the Efficacy and the Safety of Single Pill Combination (SPC) Ezetimibe/Rosuvastatin in Chinese Adult Patients With Primary Hypercholesterolemia Not Adequately Controlled on Statin Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2020-12-08

Completion:

2022-06-15

Conditions

• Hypercholesterolemia

Interventions

• DRUG

No Results Yet

NCT04667000 | COMPLETED | NA

35 participants

The Effect of Forced Air Warming During Caseraen Section on Maternal Hypothermia: Randomized Controlled Trial

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2021-05-01

Completion:

2022-09-30

Conditions

• Cesarean Section Complications
• Hypothermia

Interventions

• OTHER

No Results Yet

NCT04666311 | COMPLETED

1400 participants

Diagnostic Accuracy of CAD4TB and C-reactive Protein Assay as Triage Tests for Pulmonary Tuberculosis

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-22

Start Date:

2021-02-15

Completion:

2022-04-05

Conditions

• Pulmonary Tuberculosis
• Tuberculosis Diagnosis
• Covid-19
• HIV

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04648449 | ACTIVE_NOT_RECRUITING

1000 participants

Artificial Intelligence (AI) Support in Medical Emergency Calls

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-22

Start Date:

2020-09-01

Completion:

2026-08-31

Conditions

• Stroke, Acute
• Apoplexy; Brain
• Emergencies
• Communication, Multidisciplinary

Interventions

• OTHER

No Results Yet

NCT04625049 | ENROLLING_BY_INVITATION

100 participants

Does Microglial Activation Promote Lesion Growth and Progression Among Multiple Sclerosis Patients

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-22

Start Date:

2021-04-01

Completion:

2030-11-30

Conditions

• Multiple Sclerosis

No Results Yet

NCT04614480 | RECRUITING | PHASE2

7976 participants

Exome Analysis (Complexe vs Simple) to Help the Therapeutic Decision for the Precision Medicine

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2020-08-25

Completion:

2028-09-02

Conditions

• Cancer

Interventions

• GENETIC

No Results Yet

NCT04569409 | COMPLETED | PHASE3

104 participants

Clinical Study to Evaluate Efficacy and Safety of ALLO-ASC-DFU in Patients With Diabetic Wagner Grade 2 Foot Ulcers.

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2020-07-14

Completion:

2024-12-05

Conditions

• Diabetic Foot Ulcer

Interventions

• BIOLOGICAL
• PROCEDURE

No Results Yet

NCT04541537 | COMPLETED | NA

35 participants

Isolation of Volatile Organic Compounds (VOCs) Related to the Olfactory Signature of Breast Cancer. (KDOGCOV)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2021-01-25

Completion:

2021-12-09

Conditions

• Breast Cancer
• Surgery

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04521738 | COMPLETED | PHASE1

48 participants

First-in-human Study to Assess Safety and Tolerability of a Single Subcutaneous Dose of SAR441255 in Lean to Overweight Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2019-04-25

Completion:

2019-09-26

Conditions

• Overweight
• Healthy Subjects

Interventions

• DRUG

No Results Yet

NCT04487067 | COMPLETED | PHASE3

152 participants

A Study of Atezolizumab (Tecentriq) in Combination With Bevacizumab to Investigate Safety and Efficacy in Patients With Unresectable Hepatocellular Carcinoma Not Previously Treated With Systemic Therapy-Amethista

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2020-08-25

Completion:

2024-08-13

Conditions

• Carcinoma, Hepatocellular

Interventions

• DRUG

Results Available

NCT04450251 | COMPLETED

173 participants

Testing a Wearable Monitor for Fetal Heart Rate Estimation, Fetal Movement and Uterine Activity Detection

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-22

Start Date:

2018-08-29

Completion:

2020-05-10

Conditions

• Pregnancy

Interventions

• OTHER

No Results Yet

NCT04429295 | COMPLETED | PHASE3

460 participants

Study of DTwP-HepB-Hib-IPV (SHAN6™) Vaccine Administered Concomitantly With Routine Pediatric Vaccines to Healthy Infants and Toddlers in Thailand

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2020-06-28

Completion:

2021-02-26

Conditions

• Pertussis Immunisation
• Diphtheria Immunisation
• Polio Immunisation
• Hepatitis B Immunisation
• Haemophilus Influenzae Type B Immunisation
• Tetanus Immunisation
• Rotavirus Immunisation
• Pneumococcal Immunisation

Interventions

• BIOLOGICAL

No Results Yet

NCT04366934 | COMPLETED

26 participants

Study of the Pathogenesis of Olfactory Disorders in COVID-19

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-22

Start Date:

2020-05-04

Completion:

2020-10-29

Conditions

• Coronavirus Infection
• Severe Acute Respiratory Syndrome
• Sars-CoV2

Interventions

• OTHER

No Results Yet

NCT04269551 | COMPLETED | PHASE1

12 participants

A Safety and Tolerability Study of BIVV020 in Adults With Cold Agglutinin Disease

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2020-06-15

Completion:

2022-01-06

Conditions

• Autoimmune Haemolytic Anaemia

Interventions

• DRUG

No Results Yet

NCT04255277 | COMPLETED | PHASE1

97 participants

To Study the Effect of Cenerimod on the Electrical Activity of the Heart, in Men and Women. To Study the Effect of Cenerimod on the Use of Oral Contraceptives in Women. To Study the Effect That Charcoal Has on the Elimination of Cenerimod From the Body, in Women and Men.

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2020-01-31

Completion:

2021-09-14

Conditions

• Healthy Subjects

Interventions

• DRUG
• OTHER

No Results Yet

NCT04253379 | RECRUITING | NA

96 participants

Social Cognition in Pediatric Epilepsy

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2020-02-02

Completion:

2026-10-19

Conditions

• Pediatric Epilepsy

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04234048 | RECRUITING | PHASE1

46 participants

Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2023-12-18

Completion:

2026-12-01

Conditions

• T-cell Lymphoma
• Cutaneous/Peripheral T-Cell Lymphoma
• Peripheral T-cell Lymphoma
• Peripheral T-Cell Lymphoma, Not Classified
• Primary Cutaneous T-cell Lymphoma
• Cutaneous T-Cell Lymphoma, Unspecified
• Cutaneous T-cell Lymphoma
• Follicular T-Cell Lymphoma
• Angioimmunoblastic T-cell Lymphoma
• Sézary's Disease
• Mycosis Fungoides

Interventions

• DRUG

No Results Yet

NCT04223752 | COMPLETED | PHASE1

41 participants

Safety and Pharmacokinetics of Ceftolozane/Tazobactam in Pediatric Participants With Nosocomial Pneumonia (MK-7625A-036)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2020-04-17

Completion:

2024-09-14

Conditions

• Nosocomial Pneumonia

Interventions

• DRUG

Results Available

NCT04219163 | ACTIVE_NOT_RECRUITING | PHASE1

18 participants

Chimeric Antigen Receptor T-cells for The Treatment of AML Expressing CLL-1 Antigen

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2020-07-09

Completion:

2025-03-24

Conditions

• Acute Myeloid Leukemia

Interventions

• BIOLOGICAL

No Results Yet

NCT04199624 | COMPLETED | PHASE1

11 participants

Assessment of Gastric pH Changes Induced by Ascorbic Acid Tablets

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2021-10-01

Completion:

2023-06-07

Conditions

• Hypochlorhydria

Interventions

• DRUG
• DIETARY_SUPPLEMENT

No Results Yet

NCT04186845 | COMPLETED | PHASE3

391 participants

Imaging Study to Investigate Safety and Diagnostic Performance of 18F rhPSMA 7.3 PET Ligand in Suspected Prostate Cancer Recurrence

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2020-05-04

Completion:

2021-04-28

Conditions

• Prostate Cancer

Interventions

• DRUG
• DIAGNOSTIC_TEST

Results Available

NCT04182334 | COMPLETED | NA

160 participants

Decreasing Delirium Through Music in Critically Ill Older Adults

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2020-03-05

Completion:

2023-12-15

Conditions

• Intensive Care Unit Delirium
• Pain
• Anxiety
• Intensive Care Acquired Cognitive Impairment

Interventions

• OTHER

Results Available

NCT04158245 | COMPLETED | PHASE2

9 participants

18F-fluciclovine PET in Metastatic Castration Resistant Prostate Cancer Treated With Life Prolonging Therapies

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2020-01-30

Completion:

2022-09-30

Conditions

• Metastatic Castration-resistant Prostate Cancer

Interventions

• DRUG

Results Available

NCT04152291 | COMPLETED | NA

68 participants

The Effect of E-EPA on Circulating LDL and Plasma Lipid Metabolism

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2019-11-12

Completion:

2024-06-30

Conditions

• Atherosclerosis
• Low-density Lipoproteins Aggregation Susceptibility
• Low-density Lipoprotein Lipid Composition
• Cardiovascular Diseases

Interventions

• DIETARY_SUPPLEMENT

Results Available

NCT04142086 | COMPLETED | PHASE1

73 participants

Dose-ranging Study of an Investigational Yellow Fever Candidate Vaccine in Adults

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2020-01-15

Completion:

2021-06-24

Conditions

• Yellow Fever (Healthy Volunteers)

Interventions

• BIOLOGICAL

No Results Yet

NCT04125134 | TERMINATED | PHASE4

36 participants

Predicting the Success of Dry Eye Disease Interventions Using Clinical Tests

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2019-10-03

Completion:

2024-10-11

Conditions

• Dry Eye

Interventions

• DRUG

No Results Yet

NCT04083495 | RECRUITING | PHASE2

20 participants

CD30 CAR for Relapsed/Refractory CD30+ T Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2019-09-17

Completion:

2028-02-23

Conditions

• Peripheral T Cell Lymphoma

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04074187 | COMPLETED | PHASE2/PHASE3

21 participants

A Trial of Caplacizumab in Japanese Patients With Acquired Thrombotic Thrombocytopenic Purpura (aTTP)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2019-10-21

Completion:

2021-05-19

Conditions

• Thrombotic Thrombocytopenic Purpura

Interventions

• DRUG

No Results Yet

NCT04069884 | RECRUITING | NA

540 participants

RecurIndex Guided Avoidance of Regional Nodal Irradiation for Node Positive Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2019-08-20

Completion:

2029-08-20

Conditions

• Breast Cancer
• Radiation

Interventions

• RADIATION

No Results Yet

NCT04052360 | COMPLETED | PHASE1

20 participants

Single Oral Dose of 4 mg Cenerimod in Healthy Japanese and Caucasian Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2019-08-07

Completion:

2019-10-29

Conditions

• Healthy Volunteers

Interventions

• DRUG

No Results Yet

NCT03996447 | COMPLETED | PHASE3

260 participants

Efficacy and Safety of Gadopiclenol for Central Nervous System (CNS) Magnetic Resonance Imaging (MRI)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2019-06-03

Completion:

2020-09-11

Conditions

• CNS Lesion
• Blood Brain Barrier Defect

Interventions

• DRUG

Results Available

NCT03996070 | COMPLETED | NA

30 participants

VESPER: Stress Urinary Incontinence STUDY

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-22

Start Date:

2022-06-06

Completion:

2024-11-30

Conditions

• Female Stress Incontinence

Interventions

• PROCEDURE

No Results Yet