Clinical Trials

NCT05745714 | RECRUITING | PHASE1/PHASE2

26 participants

HEM-iSMART-C: Ruxolitinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2025-10-01

Completion:

2032-02-01

Conditions

• Acute Lymphoblastic Leukemia, in Relapse
• Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent
• Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent
• Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory
• Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory

Interventions

• DRUG

No Results Yet

NCT05738798 | ENROLLING_BY_INVITATION | NA

500 participants

Oral Immunotherapy in Young Children With Food Allergy

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2023-02-01

Completion:

2026-08-30

Conditions

• Food Allergy

Interventions

• DIETARY_SUPPLEMENT

No Results Yet

NCT05732701 | RECRUITING | NA

2788 participants

Algorithm-based Tailoring of Dual Antiplatelet Therapy to Improve Outcomes Following Percutaneous Coronary Interventions

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2023-06-27

Completion:

2027-12-31

Conditions

• Percutaneous Coronary Intervention
• Platelet Aggregation Inhibitors
• Coronary Artery Disease

Interventions

• OTHER

No Results Yet

NCT05708703 | ACTIVE_NOT_RECRUITING

78 participants

Assessing the Time Demands of Cancer

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-16

Start Date:

2023-11-13

Completion:

2024-09-09

Conditions

• Metastatic Breast Cancer
• Ovarian Cancer

Results Available

NCT05698147 | RECRUITING | PHASE1/PHASE2

30 participants

Selinexor in Combination With MTX+Ritu to Treat R/R CNSL

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2023-08-03

Completion:

2026-06-30

Conditions

• Central Nervous System Lymphoma

Interventions

• DRUG

No Results Yet

NCT05686330 | COMPLETED | NA

436 participants

Detection and Quantification of Atrial Fibrillation in High-risk Patients Using a Smartwatch Wearable (Apple Watch)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2022-11-16

Completion:

2025-07-17

Conditions

• Atrial Fibrillation

Interventions

• DEVICE

No Results Yet

NCT05670314 | COMPLETED | NA

117 participants

lIfestyle iNterventionS for PaIn ReliEf (INSPIRE)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2022-05-01

Completion:

2025-02-25

Conditions

• Osteoarthritis, Knee

Interventions

• DIETARY_SUPPLEMENT
• BEHAVIORAL

Results Available

NCT05658640 | RECRUITING | PHASE1/PHASE2

26 participants

HEM iSMART-D: Trametinib + Dexamethasone + Chemotherapy in Children With Relapsed or Refractory Hematological Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2023-11-14

Completion:

2029-04-01

Conditions

• Acute Lymphoblastic Leukemia, in Relapse
• Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Recurrent
• Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Recurrent
• Lymphoblastic Lymphoma (Precursor B-Lymphoblastic Lymphoma/Leukaemia) Refractory
• Lymphoblastic Lymphoma (Precursor T-Lymphoblastic Lymphoma/Leukaemia) Refractory

Interventions

• DRUG

No Results Yet

NCT05653544 | RECRUITING

150 participants

Natural History in Primary Mitochondrial Myopathies

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-16

Start Date:

2023-01-01

Completion:

2026-06-01

Conditions

• Primary Mitochondrial Myopathies

No Results Yet

NCT05652634 | COMPLETED

380 participants

Chronic Stress as a Risk Factor for Long COVID

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-16

Start Date:

2023-02-09

Completion:

2024-01-31

Conditions

• Long COVID
• Acute COVID-19

No Results Yet

NCT05625477 | COMPLETED | PHASE2

240 participants

Study to Compare the Anti-tetanus Neutralizing Antibody Titers and Safety of TNM002 Injection With Human Tetanus Immunoglobulin or Placebo in Adult Volunteers

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2022-04-18

Completion:

2022-05-29

Conditions

• Tetanus

Interventions

• BIOLOGICAL

Results Available

NCT05622279 | COMPLETED | NA

19 participants

Percutaneous Needle Tenotomy Associated With Platelet-rich Plasma Injection Platelet-rich Plasma in the Treatment of Refractory Plantar Fasciitis: a Pilot Study of the Effect on Pain and Tolerance

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2023-01-09

Completion:

2025-08-11

Conditions

• Plantar Fascitis

Interventions

• PROCEDURE

No Results Yet

NCT05608772 | RECRUITING | NA

234 participants

Conversion to SADI-S, RYGB or OAGB After Failed Sleeve

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2023-03-15

Completion:

2028-03-15

Conditions

• Weight Loss
• Bariatric Surgery Candidate
• Comorbidities and Coexisting Conditions
• Nutrient Deficiency

Interventions

• PROCEDURE

No Results Yet

NCT05503719 | ACTIVE_NOT_RECRUITING | NA

116 participants

An Absorbable Suture Versus a Non-absorbable Suture in Carpal Tunnel Release, a Randomized Controlled Trial

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2022-09-21

Completion:

2024-11-30

Conditions

• Carpal Tunnel Syndrome
• Median Nerve Entrapment

Interventions

• PROCEDURE

No Results Yet

NCT05502770 | RECRUITING

700 participants

Development of IVF/ICSI Children Born From Different Endometrial Preparation Protocols

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-16

Start Date:

2022-08-12

Completion:

2025-12-31

Conditions

• Child Development
• Endometrial Preparation

Interventions

• DIAGNOSTIC_TEST
• OTHER

No Results Yet

NCT05497960 | COMPLETED | NA

28 participants

Vivo Prediabetes Study: Online, Live, and Interactive Strength Training for Older Adults With Prediabetes

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2022-09-01

Completion:

2023-03-31

Conditions

• PreDiabetes
• Older Adults
• Muscle Loss
• Muscle Weakness

Interventions

• BEHAVIORAL

Results Available

NCT05488691 | COMPLETED | NA

64 participants

Eye Movement Desensitization and Reprocessing as a Treatment for Substance Use Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2022-02-01

Completion:

2025-06-01

Conditions

• Substance Use Disorders

Interventions

• BEHAVIORAL

No Results Yet

NCT05455450 | COMPLETED | NA

50 participants

Eye MOvement DesensItisation and Reprocessing Therapy (EMDR) for FunctIonal Neurological Disorder (FND)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2022-11-07

Completion:

2024-08-31

Conditions

• Functional Neurological Symptom Disorder

Interventions

• OTHER

No Results Yet

NCT05409131 | COMPLETED | NA

196 participants

Omnipod 5 System Compared to Pump Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2022-07-07

Completion:

2023-09-14

Conditions

• Type 1 Diabetes

Interventions

• DEVICE

Results Available

NCT05399732 | COMPLETED | PHASE2

58 participants

Efficacy and Safety in Transfusion Independent Non-severe Aplastic Anemia

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2022-12-19

Completion:

2025-02-01

Conditions

• Aplastic Anemia

Interventions

• DRUG

No Results Yet

NCT05391048 | COMPLETED | PHASE1

36 participants

An BE Study to Compare 10mg & 20mg of IMP4297 Capsules in Healthy Chinese Subjects Under Fed Condition

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2022-06-06

Completion:

2022-07-21

Conditions

• Solid Tumor

Interventions

• DRUG

No Results Yet

NCT05390944 | COMPLETED | PHASE1

28 participants

An BE Study to Compare 10mg & 20mg of IMP4297 Capsules in Healthy Chinese Subjects Under Fasting Condition

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2022-06-08

Completion:

2022-08-01

Conditions

• Solid Tumor

Interventions

• DRUG

No Results Yet

NCT05354427 | COMPLETED

175 participants

Retrospective Evaluation of Commercial Spacers in Prostate Cancer Patients

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-16

Start Date:

2020-06-18

Completion:

2022-01-01

Conditions

• Prostate Cancer

Interventions

• OTHER

No Results Yet

NCT05328180 | ACTIVE_NOT_RECRUITING | NA

116 participants

aDjunct bicarbonatE in Local anaesthesIa for CarpAl Tunnel rElease (DELICATE)

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2022-09-21

Completion:

2025-06-30

Conditions

• Carpal Tunnel Syndrome

Interventions

• OTHER

No Results Yet

NCT05323747 | COMPLETED

20 participants

Prospective Evaluation of a Commercially Available Hydrogel Spacer

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-16

Start Date:

2020-11-20

Completion:

2021-06-29

Conditions

• Prostate Cancer

Interventions

• OTHER

No Results Yet

NCT05317754 | ACTIVE_NOT_RECRUITING | NA

240 participants

Effectiveness of Four Deconstructive Meditative Practices on Well-being and Self-deconstruction

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2023-02-11

Completion:

2025-03-30

Conditions

• Mental Health Wellness

Interventions

• BEHAVIORAL

No Results Yet

NCT05303402 | COMPLETED | PHASE2/PHASE3

241 participants

A Phase IIb/III Clinical Trial to Assess Safety and Immunogenicity of a COVID-19 Vaccine Booster Dose in Immunosupressed Adults.

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2022-05-12

Completion:

2023-07-29

Conditions

• SARS CoV 2 Infection

Interventions

• BIOLOGICAL

No Results Yet

NCT05245331 | ACTIVE_NOT_RECRUITING | NA

20 participants

Transanal Irrigation for Low Anterior Resection Syndrome.

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2022-08-04

Completion:

2025-11-01

Conditions

• Low Anterior Resection Syndrome

Interventions

• DEVICE

No Results Yet

NCT05196113 | COMPLETED | NA

216 participants

sipIT2: Improving Adherence to Fluid Intake Guidelines for Kidney Stone Prevention

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2022-01-04

Completion:

2025-04-28

Conditions

• Urolithiasis

Interventions

• BEHAVIORAL

No Results Yet

NCT05175131 | COMPLETED | PHASE3

465 participants

Efficacy and Safety of Mebeverine + Simethicone in Patients With Functional Bowel Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2020-11-27

Completion:

2021-05-18

Conditions

• Functional Bowel Disorder

Interventions

• DRUG

Results Available

NCT05174286 | RECRUITING | NA

880 participants

Community Health Workers United to Reduce Colorectal Cancer and Cardiovascular Disease Among People at Higher Risk

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2023-03-19

Completion:

2026-06-30

Conditions

• Colorectal Cancer

Interventions

• BEHAVIORAL

No Results Yet

NCT05128773 | TERMINATED | PHASE3

3 participants

Study of Amcenestrant (SAR439859) Versus Tamoxifen for Patients With Hormone Receptor-positive (HR+) Early Breast Cancer, Who Have Discontinued Adjuvant Aromatase Inhibitor Therapy Due to Treatment-related Toxicity

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2022-02-17

Completion:

2022-10-13

Conditions

• Breast Cancer

Interventions

• DRUG

Results Available

NCT05109832 | COMPLETED | PHASE1

6 participants

A Study of Absorption-Distribution-Metabolism-Excretion (ADME) of [14C]IMP4297 to China Healthy Male Subjects

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2021-10-09

Completion:

2021-12-06

Conditions

• Solid Tumor

Interventions

• DRUG

No Results Yet

NCT05077384 | COMPLETED | PHASE1/PHASE2

36 participants

Open-label Study of Surufatinib in Japanese Patients

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2021-09-02

Completion:

2024-09-06

Conditions

• Neuroendocrine Tumors
• Non-hematologic Malignancy

Interventions

• DRUG

No Results Yet

NCT05072106 | COMPLETED | PHASE1

11 participants

Study to Evaluate the Effect of Bosentan on the Pharmacokinetics of Lurbinectedin in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2021-01-14

Completion:

2022-01-18

Conditions

• Advanced Solid Tumor

Interventions

• DRUG

Results Available

NCT05014841 | ENROLLING_BY_INVITATION | NA

52 participants

The Neural Coding of Speech Across Human Languages

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2015-09-14

Completion:

2026-08-31

Conditions

• Epilepsy
• Brain Tumor
• Speech
• Bilingualism

Interventions

• BEHAVIORAL

No Results Yet

NCT05014815 | COMPLETED | PHASE2

272 participants

Ociperlimab With Tislelizumab and Chemotherapy in Participants With Untreated Metastatic Non-Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2021-11-16

Completion:

2024-09-04

Conditions

• Locally Advanced, Unresectable, or Metastatic Nonsmall Cell Lung Cancer (NSCLC)
• Nonsmall Cell Lung Cancer, Stage IIIB
• Nonsmall Cell Lung Cancer, Stage IV

Interventions

• DRUG

Results Available

NCT04983862 | COMPLETED | PHASE1

41 participants

Fluorescent Imaging of Nerves With Illuminare-1 During Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2025-09-16

Start Date:

2021-10-04

Completion:

2025-09-09

Conditions

• Prostate Adenocarcinoma

Interventions

• DRUG
• DEVICE

No Results Yet

NCT04961398 | COMPLETED

9 participants

Evaluation of Heidelberg Engineering SPECTRALIS OCT Signal to Noise Ratio Effect on Parameter Measurements

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-16

Start Date:

2021-06-21

Completion:

2021-06-24

Conditions

• Normal Eyes

Interventions

• DEVICE

No Results Yet

NCT04918355 | COMPLETED

3635 participants

A Health System Wide Evaluation of Clinical Decision Support Tools to Improve PDMP Utilization and Patient Outcomes

Study Type:

OBSERVATIONAL

Last Updated:

2025-09-16

Start Date:

2021-02-16

Completion:

2023-05-30

Conditions

• Medication Abuse

Interventions

• OTHER

Results Available