Clinical Trials Updated in 2025

NCT05998109 | COMPLETED

30 participants

PheCheck Feasibility Study

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-15
Start Date:: 2023-12-15
Completion:: 2024-07-31

Conditions

Phenylketonurias

Interventions

DEVICE
DIAGNOSTIC_TEST

No Results Yet

NCT05994378 | COMPLETED | PHASE3

317 participants

To Compare the Efficacy and Safety of Oral SHR 7280 Tablets With Ganirelix Acetate Injection in Infertile Female Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2023-08-29
Completion:: 2025-05-02

Conditions

Infertile Female Subjects Undergoing Controlled Ovarian Hyperstimulation to Suppress Premature LH Surge and Prevent Early Ovulation

Interventions

DRUG

No Results Yet

NCT05980676 | COMPLETED | NA

150 participants

Starting a Weekday Outdoor Walking (WOW) Routine

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2024-04-11
Completion:: 2025-03-01

Conditions

Physical Inactivity

Interventions

BEHAVIORAL

No Results Yet

NCT05978700 | COMPLETED | NA

84 participants

Effectiveness of Video-game Based Swallowing Function Training in Patients With Dysphagia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2023-10-10
Completion:: 2024-06-01

Conditions

Deglutition Disorders
Rehabilitation
Video Game

Interventions

DEVICE
BEHAVIORAL

No Results Yet

NCT05970237 | RECRUITING

9000 participants

A Study to Evaluate the Efficacy and Safety of Dapagliflozin in Patient With Type 2 Diabetes Mellitus and Hypertension

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-15
Start Date:: 2023-07-26
Completion:: 2025-10-21

Conditions

Diabetes Mellitus
Hypertension

No Results Yet

NCT05954325 | COMPLETED | NA

63 participants

Immunoadsorption vs. Sham Treatment in Post COVID-19 Patients With Chronic Fatigue Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2023-08-15
Completion:: 2025-07-31

Conditions

Fatigue
Post-Acute COVID-19 Syndrome

Interventions

PROCEDURE

No Results Yet

NCT05950581 | RECRUITING | NA

32 participants

Treatment of Skeletal Class II Malocclusion With Modified Twin-Block Appliance With Clear Plates

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2026-03-15
Completion:: 2026-07-15

Conditions

Malocclusion, Angle Class II

Interventions

DEVICE

No Results Yet

NCT05944250 | COMPLETED | NA

6 participants

A Pilot Study to Evaluate a Temporary Skin Substitute (Spincare® Matrix) for Wound Healing in RDEB Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2023-09-19
Completion:: 2024-08-14

Conditions

Recessive Dystrophic Epidermolysis Bullosa

Interventions

DEVICE

Results Available

NCT05922332 | WITHDRAWN | NA

0 participants

Application and Effect Evaluation of Medium Chain Fatty Acid Rich Milk Powder in Infants With Cholestatic Liver Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2025-04-01
Completion:: 2025-12-30

Conditions

Cholestatic Liver Disease

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05916586 | COMPLETED | NA

101 participants

Effect of Short-term Prednisone Therapy on C-reactive Protein in Patients With Acute Heart Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2023-08-11
Completion:: 2024-04-21

Conditions

Acute Heart Failure

Interventions

DRUG

No Results Yet

NCT05909085 | NOT_YET_RECRUITING | NA

200 participants

The Impact of Needle Manipulation and Accuracy Between Hand Held Automatic and Traditional Ultrasound Device

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2026-07-01
Completion:: 2026-12-31

Conditions

Labor Analgesia

Interventions

DEVICE

No Results Yet

NCT05893654 | ENROLLING_BY_INVITATION | PHASE1/PHASE2

10 participants

Melphalan Chemoreduction for Ocular Melanoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2021-05-01
Completion:: 2025-12-31

Conditions

Uveal Melanoma

Interventions

DRUG
RADIATION

No Results Yet

NCT05883982 | COMPLETED | PHASE2

49 participants

Intra-articular I-PRF Injections in Patients With Temporomandibular Joint Dysfunction

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2023-06-01
Completion:: 2024-12-31

Conditions

Temporomandibular Joint Disorders
Temporomandibular Joint Pain

Interventions

PROCEDURE

No Results Yet

NCT05874544 | COMPLETED | PHASE4

360 participants

Rescue Therapy for Helicobacter Pylori Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2023-05-16
Completion:: 2025-01-31

Conditions

Helicobacter Pylori Infection

Interventions

DRUG

No Results Yet

NCT05871008 | ACTIVE_NOT_RECRUITING | NA

35 participants

Integrated Actionable Aging Assessment for Cancer Patients Pilot

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2024-03-01
Completion:: 2024-08-06

Conditions

Breast Cancer
Hodgkin Lymphoma
Kidney Cancer
Leukemia
Lymphoid Leukemia
Multiple Myeloma
Myeloid Leukemia
Monocytic Leukemia
Prostate Cancer
Bladder Cancer

Interventions

OTHER

No Results Yet

NCT05841758 | RECRUITING | PHASE4

140 participants

Hydroxychloroquine as a Steroid-sparing Agent in Extrapulmonary Sarcoidosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2024-07-30
Completion:: 2029-07-01

Conditions

Sarcoidosis, Pulmonary

Interventions

DRUG

No Results Yet

NCT05831592 | COMPLETED | NA

118 participants

Evaluation of the Validity and Reliability of Muscle Ultrasound in the Detection of Undernutrition

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2023-02-23
Completion:: 2025-01-25

Conditions

Undernutrition

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05819034 | RECRUITING | NA

60 participants

Conservative Management for Adolescent Idiopathic Scoliosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2024-02-01
Completion:: 2025-12-20

Conditions

Scoliosis; Adolescence

Interventions

OTHER

No Results Yet

NCT05806216 | COMPLETED

929 participants

Dynamic Quantification of Social-Visual Engagement in Autism Spectrum Disorder (ASD)

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-15
Start Date:: 2023-08-23
Completion:: 2025-03-27

Conditions

Autism Spectrum Disorder
Autism

Interventions

DEVICE
BEHAVIORAL

No Results Yet

NCT05797792 | ACTIVE_NOT_RECRUITING | PHASE3

440 participants

CHemical OptImization of Cerebral Embolectomy 2 (CHOICE 2).

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2023-11-18
Completion:: 2025-08-26

Conditions

Stroke, Acute Ischemic
Stroke, Acute

Interventions

DRUG

No Results Yet

NCT05782686 | RECRUITING | NA

234 participants

Impact of Systematic Shaving on Margins

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2020-10-07
Completion:: 2026-06-16

Conditions

Margin, Tumor-Free
Breast Cancer
Surgery

Interventions

PROCEDURE

No Results Yet

NCT05757817 | RECRUITING | NA

40 participants

Evaluation of the Benefit of a New Surgical Procedure According to IDEAL Recommendations for ORL Cancer Patients: the External Pudendal Flap Used as a New Free Flap for Oral Cavity/Oropharyngeal Reconstruction to Limit Donor Site Sequelae

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2023-11-08
Completion:: 2026-05-31

Conditions

Head and Neck Cancer
Oral Cavity Cancer
Oropharynx Cancer

Interventions

PROCEDURE

No Results Yet

NCT05754684 | RECRUITING | PHASE2

29 participants

Quadruple Immunotherapy for Neuroblastoma

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2022-01-01
Completion:: 2025-12-31

Conditions

Neuroblastoma Recurrent

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT05752955 | COMPLETED | NA

3446 participants

SMART Health Pregnancy 2 - Intervention to Reduce Anaemia and Cardiometabolic Risk During Pregnancy and in the First Year Following Birth

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2022-06-06
Completion:: 2024-12-31

Conditions

Anemia of Pregnancy
Gestational Diabetes
Gestational Hypertension
Pre-Eclampsia
Anemia
Type 2 Diabetes
Hypertension

Interventions

OTHER

No Results Yet

NCT05733351 | TERMINATED | PHASE1

4 participants

Vudalimab (XmAb20717) in Combination With Standard of Care Treatment in Patients With Metastatic Castration Sensitive Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2023-08-03
Completion:: 2025-06-12

Conditions

Castration-Sensitive Prostate Carcinoma
Metastatic Prostate Adenocarcinoma
Stage IVB Prostate Cancer AJCC v8

Interventions

DRUG
PROCEDURE

No Results Yet

NCT05718258 | COMPLETED | PHASE1

26 participants

A Study in Adults to Investigate the Impact of Mild, Moderate, and Severe Hepatic Impairment on Pharmacokinetics of Venglustat Compared to Participants With Normal Hepatic Function

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2023-01-18
Completion:: 2024-01-29

Conditions

Hepatic Function Abnormal

Interventions

DRUG

No Results Yet

NCT05711927 | COMPLETED | NA

20 participants

Sleep in SNOO Smart Sleeper Bassinet in Preterm Infants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2023-03-16
Completion:: 2024-05-31

Conditions

Prematurity
Very Preterm Maturity of Infant

Interventions

DEVICE

Results Available

NCT05684770 | RECRUITING | NA

50 participants

Impact of Remote Care in Patients Diagnosed With Thromboembolic Disease of Low Risk

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2025-09-30
Completion:: 2027-03-31

Conditions

Thromboembolic Disease

Interventions

OTHER

No Results Yet

NCT05684510 | RECRUITING | NA

24 participants

Treatment of Mild Class II Malocclusion in Adult Patients With Clear Aligners Versus Fixed Multibracket Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2026-08-25
Completion:: 2026-11-11

Conditions

Malocclusion
Class II Malocclusion

Interventions

DEVICE

No Results Yet

NCT05677412 | RECRUITING | NA

20 participants

Sleep, Pain and Stress in Adolescents With Persistent Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2023-05-23
Completion:: 2026-06-30

Conditions

Pain, Chronic
Sleep

Interventions

BEHAVIORAL

No Results Yet

NCT05675371 | COMPLETED

325 participants

Treatment Monitoring in Autism Spectrum Disorder (ASD) in Children

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-15
Start Date:: 2023-03-31
Completion:: 2025-09-08

Conditions

Autism Spectrum Disorder
Autism
Developmental Delay
Autism, Early Infantile
Autism, Infantile

Interventions

BEHAVIORAL
DEVICE

No Results Yet

NCT05645432 | COMPLETED | PHASE2

10 participants

An Open-Label Study Evaluating Brexanolone in Adults With Tinnitus

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2023-05-10
Completion:: 2023-11-21

Conditions

Tinnitus

Interventions

DRUG

Results Available

NCT05637775 | COMPLETED | NA

30 participants

DiSCIoser: Improving Arm Sensorimotor Functions After Spinal Cord Injury Via Brain-Computer Interface Training

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2022-11-15
Completion:: 2025-05-31

Conditions

Spinal Cord Injuries
Motor Disorders

Interventions

OTHER

No Results Yet

NCT05624112 | COMPLETED | PHASE4

44 participants

Dupilumab Skin BArrier Function and LIpidomics STudy in Atopic Dermatitis in China

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2022-11-25
Completion:: 2024-01-25

Conditions

Atopic Dermatitis
Dermatitis Atopic

Interventions

DRUG

No Results Yet

NCT05620940 | RECRUITING | PHASE1

40 participants

A Clinical Trial to Assess Pharmacokinetic Profiles, Safety and Tolerability of IVL3004 and IVL4002 in Healthy Male Subjects.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2024-09-11
Completion:: 2025-12-30

Conditions

Opioid Dependence
Alcohol Dependence
Multiple Sclerosis

Interventions

DRUG

No Results Yet

NCT05619692 | COMPLETED | PHASE2

174 participants

A Study to Evaluate the Effects of SAGE-718 in Participants With Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease (AD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2022-11-29
Completion:: 2024-06-05

Conditions

Mild Cognitive Impairment
Mild Dementia
Alzheimer's Disease

Interventions

DRUG

Results Available

NCT05582018 | TERMINATED | NA

4 participants

Safety and Effectiveness of BioTraceIO 360 for Planning, Monitoring and Assessment of Liver Tissue Ablation Procedures

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2023-09-05
Completion:: 2024-04-15

Conditions

Hepatocellular Carcinoma
Metastatic Liver Cancer

Interventions

DEVICE

No Results Yet

NCT05576025 | COMPLETED | NA

24 participants

Acute Effects of Cold-induced Shivering on 24-hour the Glucose Profile in Metabolically Compromised Populations

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2022-11-23
Completion:: 2024-11-28

Conditions

Type 2 Diabetes Mellitus
Pre-diabetes

Interventions

OTHER

No Results Yet

NCT05544344 | RECRUITING | NA

60 participants

Healthy ReStart Intervention to Improve Health and Functioning

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2022-07-01
Completion:: 2026-06-30

Conditions

Mental Disorder

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT05520034 | RECRUITING | NA

432 participants

Reduction of Recurrence of Stroke by Nurse-led Education in Bangladesh

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-15
Start Date:: 2022-10-02
Completion:: 2024-02-28

Conditions

Stroke

Interventions

BEHAVIORAL

No Results Yet