Clinical Trials Updated in 2025

NCT05369052 | RECRUITING | PHASE3

865 participants

Safety and Efficacy Study of Contezolid Acefosamil and Contezolid Compared to Linezolid Administered Intravenously and Orally to Adults With Moderate or Severe Diabetic Foot Infections (DFI)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2022-05-03
Completion:: 2026-06-30

Conditions

Diabetic Foot Infection

Interventions

DRUG

No Results Yet

NCT05366764 | COMPLETED | PHASE1

36 participants

First-in-human Study of SAR443765 in Healthy Participants and in Asthmatic Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2022-06-08
Completion:: 2023-02-24

Conditions

Asthma

Interventions

DRUG

No Results Yet

NCT05355454 | COMPLETED | NA

90 participants

Study of STYLAGE® XXL for Volume Deficiency in the Mid-Face

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2022-06-06
Completion:: 2024-05-15

Conditions

Volume Deficiency in the Mid-Face
Aging
Aesthetics

Interventions

DEVICE

No Results Yet

NCT05311033 | COMPLETED | NA

10 participants

Evaluation of a Tranexamoc Acid Treatment on Post-inflammatory Pigmentation in the Suction Blister Model

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2023-01-04
Completion:: 2024-10-29

Conditions

Skin Pigmentation

Interventions

OTHER

No Results Yet

NCT05297448 | ACTIVE_NOT_RECRUITING | PHASE3

466 participants

Evaluation of Rifaximin SSD for Delaying Encephalopathy Decompensation in Patients With Cirrhosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2022-08-03
Completion:: 2026-01-31

Conditions

Hepatic Encephalopathy

Interventions

DRUG

No Results Yet

NCT05278156 | COMPLETED | PHASE2

189 participants

Efficacy, Safety and Pharmacokinetics Study of CPL500036 (PDE10A Inhibitor) in Patients With Schizophrenia

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2021-05-19
Completion:: 2024-06-05

Conditions

Schizophrenia

Interventions

DRUG

No Results Yet

NCT05278130 | WITHDRAWN | NA

0 participants

Serial Screening and Treatment of Bacterial Vaginosis Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2022-10-20
Completion:: 2027-12-31

Conditions

Bacterial Vaginosis
Preterm Delivery

Interventions

OTHER

No Results Yet

NCT05278052 | RECRUITING | PHASE3

190 participants

Standard Maintenance Therapy (SMT) vs Local Consolidative Radiation Therapy and SMT in OM-NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2020-04-20
Completion:: 2026-04-20

Conditions

Oligometastatic Disease
Metastatic Non Small Cell Lung Cancer

Interventions

RADIATION
DRUG

No Results Yet

NCT05277844 | RECRUITING | PHASE2

106 participants

Local Consolidative Radiation Therapy Plus TKI Versus TKI Alone in Driver Mutated OM-NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2019-11-11
Completion:: 2026-11-11

Conditions

Oligometastatic Disease
Non-small Cell Lung Cancer
Driver Mutation

Interventions

RADIATION
DRUG

No Results Yet

NCT05271786 | COMPLETED

192 participants

WEANING FROM TRACHEOSTOMY

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-10
Start Date:: 2022-04-01
Completion:: 2023-11-30

Conditions

Tracheostomy Weaning
Tracheostomy Decannulation

Interventions

OTHER

No Results Yet

NCT05264870 | TERMINATED | PHASE4

11 participants

Norepinephrine in Caesarian Section

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2022-06-09
Completion:: 2023-03-02

Conditions

Cesarean Section Complications
Hemodynamic Instability
Foetal Stress

Interventions

DRUG

No Results Yet

NCT05250375 | RECRUITING

1300 participants

Natural History Study of Mitochondrial Myopathy

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-10
Start Date:: 2017-03-24
Completion:: 2030-03-24

Conditions

Primary Mitochondrial Disease

No Results Yet

NCT05246449 | COMPLETED | NA

113 participants

Evaluate the Benefit of an Individualised Treatment Plan (VitalCare) VS SOC in OSA Patients Treated With CPAP/APAP

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2022-02-15
Completion:: 2023-02-15

Conditions

Obstructive Sleep Apnoea Syndrome (OSAS)

Interventions

OTHER

No Results Yet

NCT05236946 | RECRUITING | PHASE3

190 participants

Observation or Upfront Cranial RT in Oncogene Mutated NSCLC With Asymptomatic BM: A Phase III RCT

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2020-11-10
Completion:: 2025-12-31

Conditions

Asymptomatic Brain Metastases
Driver Mutation Positive Non-small Cell Lung Cancer

Interventions

RADIATION
DRUG

No Results Yet

NCT05184322 | COMPLETED | PHASE1

87 participants

XW004 To Evaluate the Safety, Tolerability, PK, and PD of Oral Ecnoglutide Tablet in Healthy Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2022-04-12
Completion:: 2024-07-13

Conditions

Obesity
Type 2 Diabetes Mellitus

Interventions

DRUG

No Results Yet

NCT05183672 | RECRUITING | NA

196 participants

Improving Post-acute Stroke Follow-up Care by Adopting Telecare Consultations in a Nurse-led Clinic

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2022-12-01
Completion:: 2025-10-30

Conditions

Stroke

Interventions

PROCEDURE

No Results Yet

NCT05181553 | COMPLETED | NA

50 participants

Unravelling the Impact of Diet on Cardiovascular Health in Heterozygous Familial Hypercholesterolemia.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2022-01-10
Completion:: 2024-06-30

Conditions

Familial Hypercholesterolemia
Nutrition, Healthy
Cholesterol, Elevated
Cholesterol; Metabolic Disorder
Cardiovascular Diseases

Interventions

OTHER

No Results Yet

NCT05125471 | COMPLETED | PHASE2

3 participants

Cobimetinib In Extracranial Arteriovenous Malformations (COBI-AVM Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2022-07-26
Completion:: 2025-09-03

Conditions

Arteriovenous Malformations (Extracranial)

Interventions

DRUG

No Results Yet

NCT05107960 | COMPLETED

5 participants

A Study of Azilsartan in Children From 6 to Less Than 16 Years Old With High Blood Pressure

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-10
Start Date:: 2021-12-16
Completion:: 2024-08-31

Conditions

Hypertension

Interventions

DRUG

Results Available

NCT05094843 | RECRUITING

100 participants

The Cardiac Stress and Electrocardiographic Changes Caused by Lung Cancer Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-10
Start Date:: 2022-03-01
Completion:: 2028-12-31

Conditions

Lung Cancer
Surgery
Arrhythmia
Myocardial Ischemia

No Results Yet

NCT05057689 | WITHDRAWN | PHASE2

0 participants

Safety & Efficacy of Intranasal Dexmedetomidine, Fentanyl & Midazolam in the Pediatric Emergency Room

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2025-09-30
Completion:: 2025-10-31

Conditions

Acute Stress Disorder
Anxiety
Pain

Interventions

DRUG

No Results Yet

NCT05038930 | COMPLETED | NA

22 participants

Mobilising Patients With Severe Brain Injury in Intensive Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2021-10-01
Completion:: 2023-03-16

Conditions

Brain Injury Traumatic Severe
Subarachnoid Hemorrhage
Intracranial Hematoma

Interventions

DEVICE

No Results Yet

NCT05024474 | COMPLETED | NA

44 participants

Effects of Inspiratory Muscle Training After Covid-19 (ReCOV)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2021-08-24
Completion:: 2024-12-31

Conditions

Covid-19
Respiratory Complication
Post-Acute Covid-19 Syndrome

Interventions

OTHER

No Results Yet

NCT05009082 | RECRUITING | PHASE3

970 participants

Niraparib vs Niraparib Plus Bevacizumab in Patients With Platinum/Taxane-based Chemotherapy in Advanced Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2022-09-13
Completion:: 2028-12-31

Conditions

Ovarian Cancer
Fallopian Tube Cancer
Peritoneal Cancer

Interventions

DRUG

No Results Yet

NCT04992546 | COMPLETED | PHASE2

39 participants

Phase 2a Study of the Safety, Tolerability, and Pharmacokinetics of Topically Administered PRN473 (SAR444727) in Patients With Mild to Moderate Atopic Dermatitis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2021-08-13
Completion:: 2022-12-28

Conditions

Atopic Dermatitis

Interventions

DRUG

Results Available

NCT04987268 | COMPLETED

1029 participants

CHIP and Residual Cardiovascular Event Tendency After Smoking Cessation

Study Type:: OBSERVATIONAL
Last Updated:: 2025-09-10
Start Date:: 2021-08-20
Completion:: 2022-08-20

Conditions

ACS
Clonal Hematopoiesis of Indeterminate Potential
Smoking Cessation

Interventions

GENETIC

No Results Yet

NCT04932564 | TERMINATED | PHASE2

1 participants

Leflunomide for Musculoskeletal GVHD After Allogeneic Stem Cell Transplant

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2023-09-18
Completion:: 2024-06-25

Conditions

Musculoskeletal Disease Other
GVHD, Chronic

Interventions

DRUG

No Results Yet

NCT04919226 | ACTIVE_NOT_RECRUITING | PHASE3

259 participants

Lutetium 177Lu-Edotreotide Versus Best Standard of Care in Well-differentiated Aggressive Grade-2 and Grade-3 GastroEnteroPancreatic NeuroEndocrine Tumors (GEP-NETs) - COMPOSE

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2021-12-21
Completion:: 2027-06-30

Conditions

Neuroendocrine Tumors

Interventions

DRUG
OTHER

No Results Yet

NCT04869553 | COMPLETED | NA

52 participants

Analgesic Efficacy of Hypnosis and Virtual Reality in Repetitive Pain Care

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2022-01-07
Completion:: 2024-05-24

Conditions

Pain

Interventions

OTHER

No Results Yet

NCT04862676 | COMPLETED | EARLY_PHASE1

29 participants

Repeated HBO Therapy in Myeloma Patients Undergoing High-Dose Therapy and Auto-HCT

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2022-04-22
Completion:: 2025-04-04

Conditions

Myeloma

Interventions

DRUG

No Results Yet

NCT04857034 | ACTIVE_NOT_RECRUITING | PHASE2

74 participants

A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Active Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2021-07-12
Completion:: 2024-08-22

Conditions

Lupus Erythematosus, Discoid
Lupus Erythematosus, Subacute Cutaneous

Interventions

DRUG

Results Available

NCT04852562 | COMPLETED | NA

110 participants

The Effect of Modified Radical Endoscopic Sinus Surgery on Eosinopilic Chronic Rhinosinusitus With Nasal Polyps

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2020-12-06
Completion:: 2024-07-26

Conditions

Chronic Sinusitis
Endoscopic Sinus Surgery
Nasal Polyps

Interventions

PROCEDURE

No Results Yet

NCT04800419 | COMPLETED | NA

110 participants

RCT of Effects of Mindfulness-based Stress Reduction in Head and Neck Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2022-01-01
Completion:: 2023-06-30

Conditions

Cancer of Head and Neck

Interventions

BEHAVIORAL

No Results Yet

NCT04776278 | ACTIVE_NOT_RECRUITING | NA

525 participants

Behavioral Economic and Wellness-based Approaches for Reducing Alcohol Use and Consequences Among Emerging Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2022-01-17
Completion:: 2026-05-01

Conditions

Alcohol Abuse

Interventions

BEHAVIORAL
OTHER

No Results Yet

NCT04711603 | COMPLETED | PHASE3

178 participants

A Phase III Clinical Study of MR13A9 in Hemodialysis Patients With Pruritus.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2021-01-16
Completion:: 2022-01-25

Conditions

Uremic Pruritus

Interventions

DRUG

Results Available

NCT04682119 | COMPLETED | PHASE1

16 participants

A Safety Study of LY3526318 in Healthy Participants

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2020-12-29
Completion:: 2021-04-21

Conditions

Healthy

Interventions

DRUG

Results Available

NCT04681729 | COMPLETED | PHASE3

82 participants

Dupilumab for the Treatment of Chronic Inducible Cold Urticaria in Patients Who Remain Symptomatic Despite the Use of H1-antihistamine (LIBERTY-CINDU CUrIADS)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2020-12-10
Completion:: 2023-02-02

Conditions

Cold Urticaria

Interventions

DRUG

Results Available

NCT04669600 | COMPLETED | PHASE2

12 participants

A Phase 2a Study Evaluating BIVV020 in Adults With Persistent/Chronic Immune Thrombocytopenia (ITP)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2021-02-04
Completion:: 2022-02-15

Conditions

Immune Thrombocytopenia (ITP)

Interventions

DRUG

Results Available

NCT04506775 | COMPLETED | NA

30 participants

Comparison of Non-invasive and Invasive Blood Pressure Monitors

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2020-01-01
Completion:: 2024-04-18

Conditions

Blood Pressure
Surgery
Intensive Care Unit

Interventions

DEVICE
PROCEDURE

Results Available

NCT04490785 | COMPLETED | NA

38 participants

Mri characterIzation of Troponin Elevation After Cardiac Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2025-09-10
Start Date:: 2020-12-02
Completion:: 2023-01-12

Conditions

Cardiac Surgery
Cardiopulmonary Bypass

Interventions

PROCEDURE
BIOLOGICAL

No Results Yet