Clinical Trials Updated in 2025

NCT06519682 | RECRUITING | NA

20 participants

A Pilot Study Investigating Upfront Adaptive Immunotherapy Approach in Children, Adolescent and Young Adult (CAYA) Patients With Replication-Repair Deficient (RRD) High-Grade Gliomas (HGG)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2024-12-06
Completion:: 2026-12-31

Conditions

High Grade Glioma
Replication Repair Deficient

Interventions

DRUG
RADIATION

No Results Yet

NCT06509568 | RECRUITING | PHASE2

92 participants

Neoadjuvant ChemoRadiotherapy Followed by Immunotherapy and Surgery for Resectable Esophageal Squamous Cell Carcinoma（CRIS-2 Trial）

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2024-08-01
Completion:: 2026-08-01

Conditions

Esophageal Squamous Cell Carcinoma

Interventions

RADIATION
DRUG

No Results Yet

NCT06490536 | RECRUITING | PHASE3

700 participants

The Sagittarius Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2024-10-22
Completion:: 2026-03-01

Conditions

Colon Cancer Stage II
Colon Cancer Stage III

Interventions

DRUG

No Results Yet

NCT06486805 | COMPLETED | PHASE4

54 participants

N-Acetyl Cysteine Effect on Liver Function After Mitral Valve Replacement

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2024-06-30
Completion:: 2024-11-30

Conditions

Oxidative Stress
Liver Dysfunction

Interventions

DRUG
OTHER

No Results Yet

NCT06483698 | RECRUITING

20000 participants

Real-world Clinical Outcomes of Patients With Early-stage Lung Cancer After the Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-08-29
Start Date:: 2024-03-01
Completion:: 2026-03-31

Conditions

Lung Cancer

Interventions

OTHER

No Results Yet

NCT06479278 | RECRUITING | NA

66 participants

Talk With Me Baby to Enhance the Early Home Language Environment

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2025-02-03
Completion:: 2026-08-31

Conditions

Language Development
Speech
Infant Development
Infant Behavior
Language, Child
Language

Interventions

BEHAVIORAL

No Results Yet

NCT06464679 | RECRUITING | PHASE1

72 participants

An Exploratory Clinical Study of CD19 CAR NK Cell Injection for the Treatment of Relapsed/Refractory Autoimmune Diseases

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2024-06-27
Completion:: 2025-12-30

Conditions

Autoimmune Diseases

Interventions

BIOLOGICAL

No Results Yet

NCT06449612 | COMPLETED | NA

40 participants

Feasibility, Safety and Performance Evaluation of an Application Based Training Programme for Patients After a Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2024-07-26
Completion:: 2025-07-29

Conditions

Stroke

Interventions

DEVICE

No Results Yet

NCT06448585 | COMPLETED | PHASE4

60 participants

Dietary Supplement (Beta-Glucans) in Allergic Patients Undergoing Subcutaneous Immunotherapy.

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2024-05-29
Completion:: 2024-05-29

Conditions

Rhinitis
Allergic Rhinoconjunctivitis
Rhinoconjunctivitis
Controlled Asthma
Uncontrolled Asthma

Interventions

DRUG
DIETARY_SUPPLEMENT

No Results Yet

NCT06436300 | COMPLETED | NA

998 participants

Colorectal Cancer Screening in Alaska Native Men

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2023-08-01
Completion:: 2024-01-31

Conditions

Colorectal Cancer

Interventions

BEHAVIORAL

Results Available

NCT06388759 | TERMINATED | PHASE1

9 participants

TQ05105 Tablet for Myelofibrosis Treatment in Ruxolitinib-Resistant or Intolerant Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2022-08-01
Completion:: 2025-08-12

Conditions

Myelofibrosis

Interventions

DRUG

No Results Yet

NCT06378099 | RECRUITING | NA

900 participants

Evaluation of the Effect of Consensus-based Protocols for the Treatment of Minor Ailments

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2024-12-04
Completion:: 2025-06-03

Conditions

Community Pharmacy Services

Interventions

OTHER

No Results Yet

NCT06364943 | COMPLETED | NA

26 participants

Tear Ferning Test for Dry Eye Diagnosis

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2024-04-05
Completion:: 2024-05-22

Conditions

Dry Eye Syndromes

Interventions

OTHER

No Results Yet

NCT06341569 | COMPLETED | NA

128 participants

Physical Therapy Students: Well-being

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2024-05-09
Completion:: 2024-08-29

Conditions

Anxiety State
Motivation
Life Stress
Sleep, Inadequate

Interventions

OTHER

No Results Yet

NCT06272513 | COMPLETED

20 participants

Influencing Factors for Physical Activity in People With Head and Neck Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2025-08-29
Start Date:: 2024-03-30
Completion:: 2025-07-30

Conditions

Advanced Head and Neck Squamous Cell Carcinoma

No Results Yet

NCT06246552 | COMPLETED | PHASE2

480 participants

Clinical Trial to Evaluate the Safety and Efficacy of JTM201 to Treat Moderate or Severe Glabellar Lines

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2024-10-26
Completion:: 2025-06-05

Conditions

Glabellar Lines

Interventions

BIOLOGICAL

No Results Yet

NCT06202027 | RECRUITING

100 participants

Post Marketing Surveillance Study to Observe Safety and Effectiveness of CRYSVITA® in S. Korean Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2025-08-29
Start Date:: 2023-08-11
Completion:: 2031-06-16

Conditions

FGF23-related Hypophosphataemic Rickets and Osteomalacia

Interventions

DRUG

No Results Yet

NCT06174389 | RECRUITING | NA

90 participants

ADAPT Study: Assessing Diet, Appetite and Physiology Throughout Weight Loss Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2023-10-01
Completion:: 2027-07-31

Conditions

Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT06132529 | COMPLETED

151 participants

A Study to Evaluate Biomarker Signature to Predict the Persistence of Post-traumatic Headache

Study Type:: OBSERVATIONAL
Last Updated:: 2025-08-29
Start Date:: 2019-06-03
Completion:: 2025-07-31

Conditions

Post-Traumatic Headache
Healthy

Interventions

DIAGNOSTIC_TEST
OTHER

No Results Yet

NCT06102382 | RECRUITING | NA

100 participants

The Effect of Two Different Doses of Noradrenaline on Hypotension Caused by Spinal Anesthesia for Cesarean Section

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2024-09-01
Completion:: 2025-10-01

Conditions

Cesarean Section
Hypotension
Norepinephrine

Interventions

DRUG

No Results Yet

NCT06085495 | COMPLETED | NA

52 participants

Mechanical Thrombectomy for Acute Lower Limb Deep Vein Thrombosis in Tumor Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2023-01-23
Completion:: 2025-08-15

Conditions

Cancer Patients With Acute Lower Limb Deep Vein Thrombosis (DVT)

Interventions

PROCEDURE

No Results Yet

NCT06073054 | COMPLETED | NA

25 participants

A Pharmacist Intervention to Improve Mother and Child Health

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2024-01-30
Completion:: 2024-07-10

Conditions

Hypertension

Interventions

BEHAVIORAL

Results Available

NCT06069999 | ACTIVE_NOT_RECRUITING | NA

60 participants

Telerehabilitation Early After CNS Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2024-05-09
Completion:: 2025-10-30

Conditions

Cerebral Stroke
Traumatic Brain Injury
Spinal Cord Injuries

Interventions

DEVICE

No Results Yet

NCT06058351 | RECRUITING | NA

60 participants

ABI-aftercare in Motion: Multidisciplinary Aftercare in the Home Environment in Patients With Acquired Brain Injury

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2024-03-01
Completion:: 2027-01-01

Conditions

Acquired Brain Injury

Interventions

BEHAVIORAL

No Results Yet

NCT06057207 | COMPLETED

58 participants

Perioperative Blood Adiponectin Dynamics and Systemic Infflamatory Response After Major Colorectal Surgery

Study Type:: OBSERVATIONAL
Last Updated:: 2025-08-29
Start Date:: 2023-07-27
Completion:: 2025-05-01

Conditions

Obesity, Abdominal
Surgery
Systemic Inflammatory Response Syndrome
Postoperative Complications
Colorectal Carcinoma (CRC)
Adiponectin

Interventions

DIAGNOSTIC_TEST
OTHER

No Results Yet

NCT06042933 | COMPLETED | NA

100 participants

Early Oral Feeding Versus Traditional Delayed Oral Feeding Post-perforated Peptic Ulcer Repair

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2023-03-02
Completion:: 2024-10-25

Conditions

Peptic Ulcer Perforation

Interventions

OTHER

No Results Yet

NCT06040736 | COMPLETED

155 participants

Point-of-care Ultrasound to Assess Hydronephrosis in Patients With Acute Kidney Injury in the Emergency Department

Study Type:: OBSERVATIONAL
Last Updated:: 2025-08-29
Start Date:: 2020-07-02
Completion:: 2023-09-30

Conditions

Acute Kidney Injury
Urinary Tract Obstruction

No Results Yet

NCT06030505 | COMPLETED

1140 participants

Effectiveness of Nirsevimab in Children Hospitalised With RSV Bronchiolitis

Study Type:: OBSERVATIONAL
Last Updated:: 2025-08-29
Start Date:: 2023-10-15
Completion:: 2023-12-29

Conditions

Bronchiolitis, Viral

Interventions

OTHER

No Results Yet

NCT05955274 | COMPLETED | NA

56 participants

Mobile Behavioral Parent Training for Childhood ADHD: Pilot Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2024-11-01
Completion:: 2025-08-14

Conditions

Attention Deficit Hyperactivity Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT05954065 | COMPLETED

31 participants

An Evaluation of the Effect of the Erchonia Laser for Non-invasive Reduction of Submental Fat

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2023-07-12
Completion:: 2024-05-31

Conditions

Weight Loss

Interventions

DEVICE

Results Available

NCT05951439 | COMPLETED | NA

30 participants

Effect of Creatine+HMB Supplementation in Physically Active Older Adults

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2024-11-08
Completion:: 2025-02-22

Conditions

Aging
Sarcopenia
Nutrition, Healthy

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05879653 | RECRUITING | PHASE2

30 participants

Pembrolizumab and EV With Radiation Therapy for MIBC Patients (PEVRAD)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2023-10-01
Completion:: 2025-09-30

Conditions

Bladder Cancer

Interventions

DRUG
PROCEDURE
RADIATION

No Results Yet

NCT05874635 | ACTIVE_NOT_RECRUITING | NA

20000 participants

Signos DM2 Empowerment Study (SIGNOS-CGM-EMPOWER-201-2022)

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2023-05-11
Completion:: 2028-05-10

Conditions

Weight Loss
Metabolic Syndrome
Diabetes Mellitus, Type 2
Central Obesity
Insulin Resistance
Glucose Intolerance
Metabolic Glucose Disorders

Interventions

DEVICE

No Results Yet

NCT05852925 | RECRUITING | NA

2500 participants

Evaluation of Tasso+ Blood Self-Collection for Clinical Diagnostic Assessment of Various Biomarkers

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2023-07-25
Completion:: 2026-07-31

Conditions

Blood Self-Collection for Clinical Diagnostic Assessments

Interventions

OTHER
DEVICE

No Results Yet

NCT05837234 | ACTIVE_NOT_RECRUITING | NA

55 participants

Ultra Low Frequency Spinal Cord Stimulation for Chronic Low Back Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2023-05-09
Completion:: 2025-05-19

Conditions

Chronic Pain
Chronic Low-back Pain

Interventions

DEVICE

No Results Yet

NCT05815862 | COMPLETED | PHASE2

29 participants

Clinical Study of AL2846 Capsules in the Treatment of Advanced Lung Tumor and Advanced Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2023-02-15
Completion:: 2025-08-20

Conditions

Advanced Lung Cancer
Ovarian Cancer

Interventions

DRUG

No Results Yet

NCT05789862 | WITHDRAWN | NA

0 participants

Behavioral Health Evaluation and Intervention Program for Patients Undergoing Craniotomy

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2025-12-31
Completion:: 2026-12-31

Conditions

Brain Tumor

Interventions

BEHAVIORAL

No Results Yet

NCT05788978 | COMPLETED

400 participants

Endometriosis Self-Care Behaviors Scale

Study Type:: OBSERVATIONAL
Last Updated:: 2025-08-29
Start Date:: 2023-03-30
Completion:: 2024-04-01

Conditions

Endometriosis
Self Care
Behavior
Nursing Role

Interventions

OTHER

No Results Yet

NCT05763693 | NOT_YET_RECRUITING | PHASE4

4000 participants

Vitality in Infants Via Azithromycin for Neonates Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2025-08-29
Start Date:: 2026-04-30
Completion:: 2030-04-30

Conditions

Neonatal Death
Infectious Disease
Nutritional Deficiency

Interventions

DRUG
OTHER

No Results Yet

NCT05740293 | COMPLETED

186 participants

Post-approval Study of New Enrolment Patients Undergoing Bilateral Treatment With the VisuMax SMILE Procedure

Study Type:: OBSERVATIONAL
Last Updated:: 2025-08-29
Start Date:: 2022-04-05
Completion:: 2024-09-01

Conditions

Myopia
Astigmatism

Interventions

PROCEDURE

No Results Yet