Clinical Trials

NCT03941873 | COMPLETED | PHASE1/PHASE2

111 participants

A Study to Investigate Sitravatinib as Monotherapy and in Combination With Tislelizumab in Participants With Unresectable Locally Advanced or Metastatic Hepatocellular Carcinoma or Gastric/Gastroesophageal Junction Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2019-02-28

Completion:

2023-03-31

Conditions

• Carcinoma, Hepatocellular
• Gastric/Gastroesophageal Junction Cancer

Interventions

• DRUG

Results Available

NCT03926572 | COMPLETED | NA

145 participants

Acute Decompensation of Pulmonary Hypertension

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2019-09-19

Completion:

2022-12-12

Conditions

• Hypertension, Pulmonary
• Biomarkers

Interventions

• OTHER

No Results Yet

NCT03870451 | TERMINATED | NA

18 participants

Cryocompression Therapy for Peripheral Neuropathy in Patients With Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2019-11-01

Completion:

2023-02-10

Conditions

• Chemotherapy-induced Peripheral Neuropathy
• Plasma Cell Myeloma

Interventions

• DEVICE

No Results Yet

NCT03846427 | COMPLETED | PHASE2

68 participants

Study of Zanubrutinib (BGB-3111) in Participants With Marginal Zone Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2019-02-19

Completion:

2022-05-04

Conditions

• Marginal Zone Lymphoma
• MZL

Interventions

• DRUG

Results Available

NCT03721783 | RECRUITING

40 participants

Infant and Child European Cryoablation Project ICECaP

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-26

Start Date:

2021-06-24

Completion:

2027-02-01

Conditions

• Therapy
• Soft Tissue Lesion
• Cryoablation
• Pediatric

Interventions

• PROCEDURE

No Results Yet

NCT03669757 | COMPLETED | PHASE1

13 participants

Clinical Trial to Assess Safety, Tolerability and the Pharmacodynamic Effect of Different Concentrations of a New Anti-inflammatory Substance in Subjects With Chronic Plaque Psoriasis

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2018-09-27

Completion:

2019-02-01

Conditions

• Psoriasis Vulgaris

Interventions

• DRUG

No Results Yet

NCT03640325 | COMPLETED | NA

143 participants

The PRISM Intervention for Adolescents and Young Adults Receiving Hematopoietic Cell Transplantation

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2019-04-01

Completion:

2023-03-31

Conditions

• Cancer
• Bone Marrow Neoplasms
• Anxiety
• Depression
• Quality of Life
• Adherence, Medication
• Coping Skills
• Adolescent Behavior

Interventions

• BEHAVIORAL

Results Available

NCT03594747 | COMPLETED | PHASE3

360 participants

A Study of Tislelizumab in Combination With Chemotherapy Versus Chemotherapy in Advanced Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2018-07-30

Completion:

2020-09-30

Conditions

• Non-Small Cell Lung Cancer

Interventions

• DRUG

Results Available

NCT03575065 | COMPLETED | PHASE2

88 participants

Efficacy and Safety of BGB-290 in the Treatment of Metastatic HER2-Negative Breast Cancer Patients With BRCA Mutation in China

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2018-06-22

Completion:

2020-10-09

Conditions

• HER2-negative Breast Cancer

Interventions

• DRUG

Results Available

NCT03569878 | COMPLETED | NA

450 participants

IT Enhanced Peer Integrated Collaborative Care for US Trauma Care Systems

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2018-08-06

Completion:

2023-07-11

Conditions

• PTSD
• Physical Injury

Interventions

• BEHAVIORAL

Results Available

NCT03549572 | COMPLETED

56 participants

Validity and Feasibility of the CRSR-FAST

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-26

Start Date:

2018-08-28

Completion:

2022-12-04

Conditions

• Disorder of Consciousness
• Traumatic Brain Injury

Interventions

• BEHAVIORAL

Results Available

NCT03520920 | COMPLETED | PHASE2

41 participants

BTK Inhibitor BGB-3111 in Chinese Participants With Diffuse Large B-Cell Lymphoma (Non-GCB) and Indolent Lymphoma (FL and MZL)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2018-01-04

Completion:

2020-08-28

Conditions

• Marginal Zone Lymphoma
• Follicular Lymphoma
• Diffuse Large B-Cell Lymphoma

Interventions

• DRUG

Results Available

NCT03493451 | COMPLETED | PHASE2

77 participants

Study of BGB-A317 in Participants With Relapsed or Refractory Mature T- and NK-cell Neoplasms

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2018-04-13

Completion:

2021-04-21

Conditions

• Peripheral T Cell Lymphoma
• PTCL
• Extranodal NK/T-cell Lymphoma
• Extranodal NK/T-cell Lymphoma, Nasal Type
• Extranodal NK T Cell Lymphoma
• Extranodal NK T Cell Lymphoma, Nasal
• Adult Nasal Type Extranodal NK/T-cell Lymphoma
• Angioimmunoblastic T-cell Lymphoma
• Angioimmunoblastic T-Cell Lymphoma Recurrent
• Angioimmunoblastic T-Cell Lymphoma Refractory
• Peripheral T-cell Lymphoma NOS
• Peripheral T-Cell Lymphoma, Not Otherwise Specified
• Peripheral T-Cell Lymphoma Refractory
• Anaplastic Large Cell Lymphoma
• Anaplastic Large Cell Lymphoma, ALK-Positive
• Anaplastic Large Cell Lymphoma, ALK-negative
• ALK-negative Anaplastic Large Cell Lymphoma
• ALK-Positive Anaplastic Large Cell Lymphoma
• Cutaneous T-cell Lymphoma

Interventions

• DRUG

Results Available

NCT03430843 | COMPLETED | PHASE3

512 participants

A Study of Tislelizumab (BGB-A317) Versus Chemotherapy as Second Line Treatment in Participants With Advanced Esophageal Squamous Cell Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2018-01-26

Completion:

2020-12-01

Conditions

• Esophageal Squamous Cell Carcinoma (ESCC)

Interventions

• DRUG

Results Available

NCT03427814 | COMPLETED | PHASE2

136 participants

Study of BGB-290 or Placebo in Participants With Advanced or Inoperable Gastric Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2018-07-03

Completion:

2020-06-18

Conditions

• Advanced or Inoperable Gastric Cancer

Interventions

• DRUG

Results Available

NCT03419897 | COMPLETED | PHASE2

249 participants

Study of BGB-A317 in Participants With Previously Treated Unresectable HCC

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2018-04-09

Completion:

2021-06-30

Conditions

• Hepatocellular Carcinoma (HCC)

Interventions

• DRUG

Results Available

NCT03415594 | COMPLETED | PHASE1/PHASE2

8 participants

Safety, Efficacy, PD of FE203799 in Short Bowel Syndrome on Parenteral Support

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2018-05-08

Completion:

2019-11-21

Conditions

• Short Bowel Syndrome

Interventions

• DRUG

No Results Yet

NCT03379259 | TERMINATED | PHASE1/PHASE2

39 participants

Study of BGB-A333 Alone and in Combination With Tislelizumab in Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2017-11-27

Completion:

2020-09-08

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

Results Available

NCT03332173 | COMPLETED | PHASE2

44 participants

Study of BTK Inhibitor BGB-3111 in Chinese Subjects With Relapsed/Refractory Waldenström's Macroglobulinemia (WM)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2017-08-31

Completion:

2019-05-08

Conditions

• Waldenström's Macroglobulinemia (WM)

Interventions

• DRUG

Results Available

NCT03296137 | COMPLETED | PHASE1/PHASE2

25 participants

Adoptive Cell Therapy Across Cancer Diagnoses

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2017-10-13

Completion:

2020-03-13

Conditions

• Cancer

Interventions

• BIOLOGICAL
• DRUG

Results Available

NCT03206970 | COMPLETED | PHASE2

86 participants

Study to Evaluate Efficacy and Safety of BGB-3111 in Participants With Relapsed or Refractory Mantle Cell Lymphoma (MCL)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2017-03-02

Completion:

2019-02-15

Conditions

• Refractory Mantle Cell Lymphoma
• Relapsed Mantle Cell Lymphoma

Interventions

• DRUG

Results Available

NCT03206918 | COMPLETED | PHASE2

91 participants

Efficacy and Safety of Zanubrutinib in Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2017-03-09

Completion:

2018-06-15

Conditions

• Relapsed or Refractory Chronic Lymphocytic Leukemia
• Relapsed or Refractory Small Lymphocytic Lymphoma

Interventions

• DRUG

Results Available

NCT03145064 | COMPLETED | PHASE2

41 participants

Study of BTK Inhibitor Zanubrutinib in Participants With Relapsed/Refractory Non-GCB Type Diffuse Large B Cell Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2017-06-30

Completion:

2019-05-24

Conditions

• Diffuse Large B-cell Lymphoma

Interventions

• DRUG

Results Available

NCT03053440 | COMPLETED | PHASE3

201 participants

A Study Comparing BGB-3111 and Ibrutinib in Participants With Waldenström's Macroglobulinemia (WM)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2017-01-25

Completion:

2022-06-21

Conditions

• Waldenström's Macroglobulinemia

Interventions

• DRUG

Results Available

NCT02950155 | COMPLETED | PHASE3

47 participants

A Study Evaluating the Safety and Efficacy of Rituximab in Patients With Myasthenia Gravis

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2016-10-16

Completion:

2021-01-30

Conditions

• Generalized Myasthenia Gravis

Interventions

• DRUG

Results Available

NCT02569476 | COMPLETED | PHASE1

119 participants

BGB 3111 in Combination With Obinutuzumab in Participants With B-Cell Lymphoid Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2016-01-13

Completion:

2020-09-02

Conditions

• B-cell Lymphoid Malignancies

Interventions

• DRUG

Results Available

NCT02470585 | TERMINATED | PHASE3

1140 participants

Veliparib With Carboplatin and Paclitaxel and as Continuation Maintenance Therapy in Adults With Newly Diagnosed Stage III or IV, High-grade Serous, Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2015-07-14

Completion:

2019-05-03

Conditions

• Ovarian Cancer
• Ovarian Neoplasm

Interventions

• DRUG
• OTHER

Results Available

NCT02438683 | COMPLETED | PHASE1

20 participants

BI 409306 Cardiac Safety Trial in Healthy Volunteers

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2015-05-04

Completion:

2015-08-12

Conditions

• Healthy

Interventions

• DRUG

Results Available

NCT02295085 | ACTIVE_NOT_RECRUITING

9782 participants

Fernald Community Cohort -18 Year Observational Study

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-26

Start Date:

1990-09-30

Completion:

2025-12-31

Conditions

• Cancer
• Renal Failure
• Diabetes
• Cardiovascular Disease

No Results Yet

NCT02122666 | COMPLETED

27 participants

Composition & Function of Sarcoplasmic Reticulum in Persons With the Metabolic Syndrome

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-26

Start Date:

2014-03-31

Completion:

2024-02-15

Conditions

• Metabolic Syndrome

Interventions

• PROCEDURE

Results Available

NCT01932372 | COMPLETED

9968 participants

Tofacitinib (Xeljanz) Special Investigation for Rheumatoid Arthritis

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-26

Start Date:

2013-07-26

Completion:

2021-08-24

Conditions

• Rheumatoid Arthritis

Interventions

• DRUG

Results Available

NCT01766739 | COMPLETED | PHASE1

18 participants

Intra-pleural Administration of GL-ONC1, a Genetically Modified Vaccinia Virus, in Patients With Malignant Pleural Effusion: Primary, Metastases and Mesothelioma

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2013-01-31

Completion:

2024-10-24

Conditions

• Lung Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT00748618 | COMPLETED | NA

116 participants

Vitamin D Replacement After Kidney Transplant

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-26

Start Date:

2008-10-01

Completion:

2012-04-01

Conditions

• Kidney Transplantation
• Vitamin D Deficiency

Interventions

• DIETARY_SUPPLEMENT

Results Available

NCT06657781 | RECRUITING

171 participants

Study and Role of Inflammasome in Platelet Activation During Bacterial And/or Viral Sepsis

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-24

Start Date:

2022-11-30

Completion:

2026-11-30

Conditions

• Bacterial Sepsis

No Results Yet

NCT06657755 | COMPLETED

12 participants

Evaluation of ENPP1 Expression and Immune Response in Bladder Cancer Patients

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-24

Start Date:

2024-06-01

Completion:

2024-10-01

Conditions

• Bladder (Urothelial, Transitional Cell) Cancer

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT06657742 | COMPLETED

90 participants

Validity and Reliability of SCIM-SR

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-24

Start Date:

2023-10-16

Completion:

2024-06-16

Conditions

• Spinal Cord Injuries

Interventions

• OTHER

No Results Yet

NCT06657664 | COMPLETED | NA

45 participants

Effect of Cryotherapy and Laser Application on Post-Operative Pain in Single Visit Endodontically Treated Symptomatic Apical Periodontitis Cases

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2023-08-01

Completion:

2024-09-01

Conditions

• Irriversible Pulpitis With Apical Peridontitis
• Hot Tooth

Interventions

• PROCEDURE
• DEVICE

No Results Yet

NCT06657625 | ENROLLING_BY_INVITATION

600 participants

Impact of the Introduction of a Performance Improvement Program on the Initial Management of Sepsis and Septic Shock in Adults in the Emergency Department: a Before-and-after Study (IPA-SOS)

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-24

Start Date:

2024-08-01

Completion:

2026-07-31

Conditions

• Sepsis
• Septic Shock
• Critical Illness
• Emergency Medicine
• Surviving Sepsis Campaign
• Sepsis Performance Improvement Program
• Sepsis Team

Interventions

• OTHER

No Results Yet

NCT06657573 | NOT_YET_RECRUITING | NA

1200 participants

Vaccine Chatbot for Improving Influenza Vaccination Uptake

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2024-10-26

Completion:

2025-02-15

Conditions

• Influenza Vaccines

Interventions

• BEHAVIORAL

No Results Yet

NCT06657534 | RECRUITING | NA

150 participants

SISIPUSH: Evaluation of Hemolysis and Iatrogenic Anemia Using the Push-pull Method to Obtain Blood from Pediatric Patients with Central Venous Catheters

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2024-10-14

Completion:

2025-09-01

Conditions

• Pediatrics
• Central Venous Catheter

Interventions

• PROCEDURE

No Results Yet