Clinical Trials

NCT04776850 | WITHDRAWN | EARLY_PHASE1

0 participants

Pre-transplant Immunosuppression and Donor Stem Cell Transplant for the Treatment of Severe Hemoglobinopathies

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2020-12-29

Completion:

2022-12-05

Conditions

• Beta Thalassemia Major
• Sickle Beta 0 Thalassemia
• Sickle Beta Plus Thalassemia
• Sickle Beta Thalassemia
• Sickle Cell Disease
• Sickle Cell-SS Disease

Interventions

• DRUG
• PROCEDURE
• BIOLOGICAL

No Results Yet

NCT04766853 | COMPLETED | PHASE1/PHASE2

15 participants

Verification of the Efficacy/safety of the Intratympanic Drug Delivery for Hearing Loss

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2021-07-22

Completion:

2023-04-18

Conditions

• Hearing Loss, Sudden
• Hearing Loss, Ototoxic
• Hearing Loss, Noise-Induced
• Meniere Disease

Interventions

• DRUG

No Results Yet

NCT04723355 | COMPLETED | NA

231 participants

A Comparative Study of an Innovative 3-lead Wireless Water Resistant Holter System and a Conventional Holter System

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2021-01-26

Completion:

2021-11-16

Conditions

• Cardiac Arrhythmia

Interventions

• DEVICE

Results Available

NCT04714372 | COMPLETED | PHASE1

9 participants

FT538 in Combination With Daratumumab in AML Acute Myeloid Leukemia

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2021-11-03

Completion:

2024-01-09

Conditions

• Acute Myeloid Leukemia
• Myeloid Leukemia
• Monocytic Leukemia

Interventions

• DRUG

Results Available

NCT04714086 | NO_LONGER_AVAILABLE

Expanded Access Program for Avapritinib

Study Type:

EXPANDED_ACCESS

Last Updated:

2024-10-24

Conditions

• Solid Tumors

Interventions

• DRUG

No Results Yet

NCT04709549 | COMPLETED | NA

45 participants

ObeSity and Jobs in SoCioeconomically Disadvantaged CommUnities: A Randomized CLinical Precision Public HealTh Intervention --The SCULPT-Job Study

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2021-02-10

Completion:

2024-01-20

Conditions

• Weight Maintenance
• Weight Loss
• Stress, Psychological
• Job Stress
• Diabetes Prevention
• Obesity
• Cardiovascular Risk Factor
• Cardiovascular Diseases

Interventions

• BEHAVIORAL

No Results Yet

NCT04690699 | TERMINATED | PHASE1/PHASE2

4 participants

LUMINOS-103: A Basket Trial of Safety & Efficacy of Lerapolturev With or Without Checkpoint Inhibitors

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2021-08-01

Completion:

2024-04-04

Conditions

• Solid Tumor
• Bladder Cancer
• Non-muscle-invasive Bladder Cancer

Interventions

• BIOLOGICAL
• OTHER

Results Available

NCT04661813 | COMPLETED | NA

81 participants

Assess and Adapt to the Impact of COVID-19 on CVD Self-Management and Prevention Care in Adults Living With HIV

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2021-03-01

Completion:

2023-01-15

Conditions

• HIV-1-infection
• Hypertension

Interventions

• OTHER

Results Available

NCT04641286 | RECRUITING

8000 participants

Clinical Outcome Modelling of Rapid Dynamics in Acute Stroke

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-24

Start Date:

2021-07-07

Completion:

2028-02-29

Conditions

• Stroke

Interventions

• OTHER

No Results Yet

NCT04607174 | RECRUITING | NA

20 participants

Voluntary Activation During Isokinetic Contractions in Subjects with Neuromotor Disorders

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2020-10-07

Completion:

2024-12-31

Conditions

• Multiple Sclerosis
• Poststroke/CVA Hemiparesis
• Parkinson Disease
• Knee Impairment

Interventions

• OTHER

No Results Yet

NCT04533711 | COMPLETED | NA

240 participants

Physical Activity Pathway for Patients With Osteoarthritis in Primary Care (OA-PCP) (R33)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2020-11-30

Completion:

2023-12-04

Conditions

• Osteoarthritis

Interventions

• BEHAVIORAL

Results Available

NCT04516681 | RECRUITING | PHASE3

400 participants

Combination of IV Ascorbic Acid and Adebrelimab in Metastatic Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2024-12-01

Completion:

2025-12-01

Conditions

• Colorectal Cancer
• Vitamin C
• GLUT3

Interventions

• DRUG

No Results Yet

NCT04513158 | TERMINATED | PHASE2

2 participants

Convalescent Plasma in the Early Treatment of High-Risk Patients With SARS-CoV-2 (COVID-19) Infection

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2020-08-14

Completion:

2021-04-28

Conditions

• Covid19

Interventions

• BIOLOGICAL

Results Available

NCT04491279 | COMPLETED | NA

30 participants

Neuropilates Compared to General Exercise Classes in Chronic Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2020-10-30

Completion:

2021-04-30

Conditions

• Stroke

Interventions

• PROCEDURE

No Results Yet

NCT04464655 | RECRUITING

2130 participants

A 10-Minute Cardiovascular Magnetic Resonance Protocol for Cardiac Disease

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-24

Start Date:

2019-12-12

Completion:

2024-11-30

Conditions

• Coronary Artery Disease
• Myocarditis
• Infiltrative Cardiomyopathy
• Dilated Cardiomyopathy
• Hypertrophic Cardiomyopathy
• Aortic Valve Stenosis
• Aortic Valve Regurgitation
• Pericardial Effusion
• Congenital Heart Disease
• Vascular Anomaly

No Results Yet

NCT04420793 | COMPLETED

11 participants

Voice Changes During ECT

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-24

Start Date:

2019-11-07

Completion:

2021-02-17

Conditions

• Unipolar Depression
• Bipolar Depression
• Bipolar Disorder, Manic

Interventions

• OTHER

No Results Yet

NCT04358458 | TERMINATED | PHASE1/PHASE2

46 participants

First-in-Human (FIH) Trial of GEN3009 in Subjects With Relapsed or Refractory B-Cell Non-Hodgkin Lymphomas

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2020-03-13

Completion:

2022-11-21

Conditions

• Diffuse Large B-cell Lymphoma
• Follicular Lymphoma
• Marginal Zone Lymphoma
• Small Lymphocytic Lymphoma
• Mantle Cell Lymphoma
• Chronic Lymphocytic Leukemia
• High-grade B-cell Lymphoma
• Primary Mediastinal Large B-cell Lymphoma

Interventions

• BIOLOGICAL

Results Available

NCT04333966 | COMPLETED | NA

202 participants

Parental Research on Interventions for Social Media

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2023-02-01

Completion:

2024-03-15

Conditions

• Underage Drinking

Interventions

• BEHAVIORAL

Results Available

NCT04327362 | WITHDRAWN | NA

0 participants

TDCS-Augmented Prolonged Exposure Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2021-10-01

Completion:

2022-05-01

Conditions

• Posttraumatic Stress Disorder
• PTSD
• Anxiety
• Depression

Interventions

• DEVICE
• BEHAVIORAL

No Results Yet

NCT04264520 | TERMINATED | NA

5 participants

Initial Intervention Efficacy for an Online PTSD Intervention for Pregnant Women

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2020-06-05

Completion:

2021-04-23

Conditions

• Perinatal Problems
• Post Traumatic Stress Disorder
• Post Partum Depression

Interventions

• BEHAVIORAL

No Results Yet

NCT04258618 | COMPLETED | NA

2 participants

Cognitive Behavioral Therapy for Insomnia with RTMS

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2020-08-04

Completion:

2021-01-31

Conditions

• Depression
• Insomnia

Interventions

• BEHAVIORAL
• DEVICE

No Results Yet

NCT04238481 | COMPLETED | PHASE2

13 participants

A Study for Ureter Visualization, Using ASP5354 in Subjects Undergoing Laparoscopic/Minimally Invasive Colorectal Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2020-10-06

Completion:

2021-11-18

Conditions

• Laparoscopic/Minimally Invasive Colorectal Surgery

Interventions

• DRUG

Results Available

NCT04126148 | RECRUITING

350 participants

Breathing-Maneuver-Induced Myocardial Oxygenation Reserve Validated by FFR (B-MORE)

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-24

Start Date:

2019-07-04

Completion:

2024-12-31

Conditions

• Coronary Artery Stenosis

No Results Yet

NCT04091217 | COMPLETED | PHASE2

43 participants

Atezolizumab in Combination With Bevacizumab in Patients With Unresectable Locally Advanced or Metastatic Mucosal Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2019-11-25

Completion:

2022-08-31

Conditions

• Melanoma

Interventions

• DRUG

Results Available

NCT04058561 | ACTIVE_NOT_RECRUITING | NA

210 participants

Hospital-Based Cluster Trial: Magnetically Controlled Growing Rods Using Distraction Intervals

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2019-11-01

Completion:

2027-12-31

Conditions

• Early-Onset Scoliosis Deformity of Spine

Interventions

• DEVICE

No Results Yet

NCT03977779 | RECRUITING | NA

46 participants

Evaluation of the Use of a Biodegradable Endoprothesis in the Prevention of Post-Endoscopic Retrograde CholoangioPancreatography Pancreatitis

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2022-01-20

Completion:

2024-12-01

Conditions

• Obstructive Jaundice
• Biliary Stricture
• Sphincter of Oddi Dysfunction

Interventions

• DEVICE

No Results Yet

NCT03947229 | ACTIVE_NOT_RECRUITING | PHASE4

3200 participants

A Randomized Comparison of CLOpidogrel Monotherapy Versus Extended Dual-antiplatelet Therapy Beyond 12 Months After Implantation of Drug-eluting StEnts in High-risk Lesions or Patients; A-CLOSE Trial

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2019-08-14

Completion:

2025-08-16

Conditions

• Coronary Artery Disease
• DES

Interventions

• DRUG

No Results Yet

NCT03885284 | COMPLETED | PHASE1

9 participants

Study of Proton Therapy in Adjuvant Pancreatic Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2019-07-15

Completion:

2022-05-24

Conditions

• Resected Pancreatic Adenocarcinoma

Interventions

• DRUG
• RADIATION

Results Available

NCT03871491 | COMPLETED | PHASE3

58747 participants

Azithromycin-Prevention in Labor Use Study (A-PLUS)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2020-09-01

Completion:

2022-09-30

Conditions

• Maternal Death
• Maternal Infections Affecting Fetus or Newborn
• Neonatal SEPSIS
• Maternal Sepsis During Labor
• Neonatal Death
• Postpartum Sepsis

Interventions

• DRUG

Results Available

NCT03851510 | TERMINATED

57 participants

Determination of the Prevalence and Severity of Expiratory Flow Limitation in Chronic Obstructive Pulmonary Disease Patients

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2019-03-14

Completion:

2023-11-15

Conditions

• Chronic Obstructive Pulmonary Disease
• Noninvasive Ventilation

Interventions

• DEVICE

Results Available

NCT03844672 | COMPLETED | NA

93 participants

Impact of E-cigarette Characteristics on Reinforcement and Tobacco Use Patterns

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2019-04-01

Completion:

2023-10-17

Conditions

• Smoking
• Tobacco Use

Interventions

• BEHAVIORAL

Results Available

NCT03842137 | COMPLETED | NA

62 participants

tDCS to Decrease Opioid Relapse (UG3)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2019-06-04

Completion:

2023-04-30

Conditions

• Opioid Dependence
• Craving

Interventions

• DEVICE

Results Available

NCT03797560 | COMPLETED | NA

104 participants

Comparison of Ba-Duan-Jin and Pregabalin in Patients with Fibromyalgia

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2019-03-22

Completion:

2021-10-31

Conditions

• Fibromyalgia

Interventions

• OTHER
• DRUG

No Results Yet

NCT03684655 | RECRUITING | PHASE2

30 participants

Imaging Immune Activation in HIV by PET-MR

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2018-09-21

Completion:

2025-10-01

Conditions

• HIV Infections

Interventions

• DRUG

No Results Yet

NCT03639623 | COMPLETED | PHASE2

20 participants

Safety, Tolerability, and Efficacy of Saroglitazar Mg 4 mg in Liver Transplant Recipients With Nonalcoholic Fatty Liver Disease (NAFLD)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2019-02-25

Completion:

2021-12-13

Conditions

• Liver Transplant; Complications
• NAFLD

Interventions

• DRUG

Results Available

NCT03615222 | COMPLETED

377 participants

Impact of Modifiable Psychosocial Factors on Veterans' Long-term Trajectories of Functioning and Quality of Life

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-24

Start Date:

2018-10-01

Completion:

2023-09-30

Conditions

• PTSD
• Depression
• Chronic Pain
• Alcohol Use Disorder
• Traumatic Brain Injury

Results Available

NCT03501992 | COMPLETED | NA

9242 participants

Multilevel Interventions to Enhance Provider Recommendations for HPV Vaccination

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2018-04-01

Completion:

2022-08-31

Conditions

• Papillomavirus Vaccines

Interventions

• BEHAVIORAL

Results Available

NCT03486730 | COMPLETED | PHASE1/PHASE2

72 participants

BT1718 in Patients with Advanced Solid Tumours.

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2018-01-24

Completion:

2023-11-20

Conditions

• Advanced Solid Tumours
• Non-Small Cell Lung Cancer
• Non-Small Cell Lung Sarcoma
• Oesophageal Cancer

Interventions

• DRUG

No Results Yet

NCT03430310 | COMPLETED | NA

65 participants

Return of First-phase Insulin Secretion in Type 2 Diabetes is Associated With Depletion of Pancreas Lipid

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2018-10-09

Completion:

2023-07-31

Conditions

• Type 2 Diabetes Mellitus

Interventions

• OTHER

Results Available

NCT03429075 | COMPLETED | PHASE2

59 participants

Psilocybin vs Escitalopram for Major Depressive Disorder: Comparative Mechanisms

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-24

Start Date:

2019-01-07

Completion:

2020-04-17

Conditions

• Depressive Disorder, Major

Interventions

• DRUG

Results Available