Clinical Trials

NCT04058067 | COMPLETED | PHASE3

266 participants

To Compare Brolucizumab to Aflibercept in Chinese Patients With Visual Impairment Due to Diabetic Macular Edema

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2019-08-23

Completion:

2023-01-31

Conditions

• Diabetic Macular Edema

Interventions

• DRUG

Results Available

NCT04053764 | COMPLETED | PHASE2

58 participants

Study Exploring the Effect of Crizanlizumab on Kidney Function in Patients With Chronic Kidney Disease Caused by Sickle Cell Disease

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2019-12-10

Completion:

2023-03-20

Conditions

• Sickle Cell Disease (SCD)

Interventions

• DRUG

Results Available

NCT04005352 | COMPLETED | PHASE3

734 participants

Study to Assess the Efficacy and Safety of Brolucizumab 6mg Compared to Aflibercept 2 mg in a Treat-to-control Regimen (TALON)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2019-09-25

Completion:

2022-09-09

Conditions

• Age-related Macular Degeneration

Interventions

• BIOLOGICAL

Results Available

NCT03990597 | WITHDRAWN | PHASE1

0 participants

StrataXRT in Preventing Radiation Dermatitis in Pediatric Patients Undergoing Radiation Therapy to the Brain or Spinal Cord

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2019-08-19

Completion:

2020-11-24

Conditions

• Central Nervous System Sarcoma
• Ependymoma
• Glioma
• Malignant Intracranial Germ Cell Tumor
• Medulloblastoma
• Pineoblastoma
• Primary Central Nervous System Neoplasm

Interventions

• OTHER
• DRUG

No Results Yet

NCT03926507 | COMPLETED | NA

12 participants

F18 Fluciclovine PET/CT in Assessing Tumor Volume and Radiation Therapy Response in Patients With Glioblastoma Undergoing Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2019-04-30

Completion:

2023-09-18

Conditions

• Glioblastoma

Interventions

• PROCEDURE
• OTHER

No Results Yet

NCT03879434 | COMPLETED

110 participants

Routine Application of Ostenil® Mini in Patients with Rhizarthrosis

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-09

Start Date:

2019-04-17

Completion:

2024-05-16

Conditions

• Rhizarthrosis

Interventions

• DEVICE

No Results Yet

NCT03872349 | COMPLETED | NA

18 participants

Effects of Monounsaturated Fatty Acids on Intestinal Lipid Metabolism in Insulin Resistant Subjects (MUFA )

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2020-02-09

Completion:

2024-02-19

Conditions

• Metabolic Syndrome

Interventions

• OTHER

No Results Yet

NCT03839823 | COMPLETED | PHASE2

222 participants

Study to Compare the Combination of Ribociclib Plus Goserelin Acetate With Hormonal Therapy Versus Combination Chemotherapy in Premenopausal or Perimenopausal Patients With Advanced or Metastatic Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2019-02-25

Completion:

2022-04-12

Conditions

• Breast Cancer

Interventions

• COMBINATION_PRODUCT
• DRUG

Results Available

NCT03819894 | ACTIVE_NOT_RECRUITING | NA

24000 participants

Hs-cTn - Optimizing the Diagnosis of Acute Myocardial Infarction/Injury in Women

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2020-02-08

Completion:

2025-03-31

Conditions

• Myocardial Infarction
• Sex Differences
• High Sensitivity Troponin

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03800823 | ACTIVE_NOT_RECRUITING | NA

300 participants

Overweight and Obesity in Preschoolers

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2019-02-15

Completion:

2022-12-31

Conditions

• Obesity
• Overweight

Interventions

• BEHAVIORAL

No Results Yet

NCT03787134 | COMPLETED | NA

184 participants

Oscillatory Contributions to Working Memory and Attention

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2019-03-01

Completion:

2023-04-21

Conditions

• Young Adults

Interventions

• BEHAVIORAL

Results Available

NCT03776136 | COMPLETED | PHASE2

103 participants

Efficacy and Safety of Lenvatinib (E7080/MK-7902) Plus Pembrolizumab (MK-3475) for Advanced Melanoma in Anti-Programmed Death-1/Programmed Death-Ligand 1 (PD-1/L1)-Exposed Participants (MK-7902-004/E7080-G000-225/LEAP-004)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2019-01-30

Completion:

2023-10-11

Conditions

• Advanced Melanoma

Interventions

• DRUG
• BIOLOGICAL

Results Available

NCT03759873 | COMPLETED | PHASE2

209 participants

Incentives and Case Management to Improve Cardiac Care: Healthy Lifestyle Program

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2018-12-03

Completion:

2023-05-01

Conditions

• Cardiac Rehabilitation

Interventions

• BEHAVIORAL

Results Available

NCT03741699 | COMPLETED | PHASE3

88 participants

Recombinant LH Prior to Ovarian Stimulation in Poor Ovarian Responders (PRE-LH)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2019-02-18

Completion:

2024-05-11

Conditions

• Infertility, Female

Interventions

• DRUG

No Results Yet

NCT03741400 | COMPLETED | NA

60 participants

Virtual Reality Glove for Hand and Arm Rehabilitation After Stroke

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2018-10-01

Completion:

2023-09-15

Conditions

• Stroke, Acute
• Cerebral Infarction

Interventions

• DEVICE

Results Available

NCT03734315 | COMPLETED

115 participants

Routine Application of Ostenil® in Patients with Gonarthrosis

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-09

Start Date:

2019-01-08

Completion:

2023-01-12

Conditions

• Gonarthrosis

Interventions

• DEVICE

No Results Yet

NCT03714828 | COMPLETED | PHASE2

11 participants

Study of TVEC in Patients With Cutaneous Squamous Cell Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2018-12-20

Completion:

2023-07-19

Conditions

• Squamous Cell Carcinoma
• Skin Cancer
• Keratoacanthoma
• Cutaneous Tumor
• Skin Cancer, Squamous Cell
• Lesion Skin

Interventions

• DRUG

Results Available

NCT03713632 | COMPLETED | PHASE3

545 participants

Study of Efficacy and Safety of Two Secukinumab Dose Regimens in Subjects With Moderate to Severe Hidradenitis Suppurativa (HS)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2019-02-25

Completion:

2021-09-23

Conditions

• Hidradenitis Suppurativa

Interventions

• DRUG

Results Available

NCT03713619 | COMPLETED | PHASE3

544 participants

This Was a Study of Efficacy and Safety of Two Secukinumab Dose Regimens in Subjects With Moderate to Severe Hidradenitis Suppurativa (HS).

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2019-01-31

Completion:

2021-10-01

Conditions

• Hidradenitis Suppurativa

Interventions

• DRUG

Results Available

NCT03690661 | COMPLETED | NA

43 participants

Using Serious Games to Improve Social Skills in Autism

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2019-12-01

Completion:

2024-01-31

Conditions

• Autism Spectrum Disorder
• Autism

Interventions

• BEHAVIORAL

No Results Yet

NCT03654599 | COMPLETED | NA

202 participants

Effects of Digital Stories Intervention on Psychosocial Well-being

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2017-09-01

Completion:

2021-01-05

Conditions

• Bone Marrow Transplant
• Information Disclosure
• Hematopoietic Stem Cell Transplantation
• Psychosocial Health
• Depression
• Anxiety
• Stress
• Narrative

Interventions

• BEHAVIORAL

Results Available

NCT03634475 | COMPLETED | PHASE1/PHASE2

12 participants

A Safety Study of Intravitreal PP-001 in Patients With Chronic, Non-Infectious Uveitis

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2017-01-31

Completion:

2018-11-30

Conditions

• Non-infectious Uveitis

Interventions

• DRUG

Results Available

NCT03610516 | COMPLETED | PHASE2

57 participants

Safety, Pharmacokinetics and Preliminary Efficacy Study of CFZ533 in Patients With Lupus Nephritis.

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2018-09-12

Completion:

2023-06-29

Conditions

• Lupus Nephritis

Interventions

• DRUG

Results Available

NCT03566797 | RECRUITING

380 participants

Secondary Sclerosis Cholangitis Prospective

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-09

Start Date:

2018-07-20

Completion:

2026-12-31

Conditions

• Secondary Sclerosis Cholangitis in Critically Ill Patients

No Results Yet

NCT03526900 | COMPLETED | PHASE2

40 participants

Atezolizumab in Combination With Carboplatin Plus Pemetrexed in Chemotherapy-naïve Patients With Asymptomatic Brain Metastasis

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2018-07-07

Completion:

2022-03-31

Conditions

• Non-small Cell Lung Cancer Stage IV

Interventions

• DRUG

Results Available

NCT03473769 | WITHDRAWN | NA

0 participants

Sepsis Pre-Alert Monitoring Intervention: Study to Investigate Targeted Enhanced Monitoring for Sepsis

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2024-09-01

Completion:

2025-06-30

Conditions

• Sepsis

Interventions

• OTHER

No Results Yet

NCT03466268 | COMPLETED | PHASE1

56 participants

Study to Evaluate the Safety and Anti-tumor Activity of SCC244

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2017-09-14

Completion:

2023-01-09

Conditions

• Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT03452137 | TERMINATED | PHASE3

406 participants

A Study of Atezolizumab (Anti-PD-L1 Antibody) as Adjuvant Therapy After Definitive Local Therapy in Patients With High-Risk Locally Advanced Squamous Cell Carcinoma of the Head and Neck

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2018-04-03

Completion:

2023-09-27

Conditions

• Locally Advanced Squamous Cell Carcinoma of the Head and Neck (SCCHN)

Interventions

• DRUG

Results Available

NCT03447769 | TERMINATED | PHASE3

1382 participants

Brief Title: Study of Efficacy and Safety of Canakinumab as Adjuvant Therapy in Adult Subjects With Stages AJCC/UICC v. 8 II-IIIA and IIIB (T>5cm N2) Completely Resected Non-small Cell Lung Cancer Acronym: CANOPY-A

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2018-03-16

Completion:

2022-03-17

Conditions

• Non-Small Cell Lung Cancer

Interventions

• DRUG

Results Available

NCT03350607 | COMPLETED

9 participants

" Sweeper " and Epiretinal Membrane Surgery

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-09

Start Date:

2018-01-24

Completion:

2023-12-13

Conditions

• Epiretinal Membrane

Interventions

• OTHER

No Results Yet

NCT03268876 | ACTIVE_NOT_RECRUITING

70 participants

The INFLUENCE of Cytoreduction on PRO in EOC

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-09

Start Date:

2021-03-03

Completion:

2025-12-28

Conditions

• Epithelial Ovarian Cancer

No Results Yet

NCT03265288 | COMPLETED | PHASE2

166 participants

Study of LAU-7b in the Treatment of Cystic Fibrosis in Adults

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2018-11-05

Completion:

2021-09-15

Conditions

• Cystic Fibrosis

Interventions

• DRUG

Results Available

NCT03264989 | COMPLETED | PHASE2

57 participants

Pharmacokinetics and Pharmacodynamics Study of SEG101 (Crizanlizumab) in Sickle Cell Disease (SCD) Patients With Vaso- Occlusive Crisis (VOC)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2017-12-19

Completion:

2023-06-26

Conditions

• Sickle Cell Disease (SCD)

Interventions

• DRUG

Results Available

NCT03240263 | COMPLETED | NA

90 participants

Inspiratory Muscle Training in Difficult to Wean Patients

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2017-09-01

Completion:

2023-08-01

Conditions

• Weaning Failure

Interventions

• PROCEDURE

No Results Yet

NCT03214029 | ACTIVE_NOT_RECRUITING

2000 participants

COmparisoN of High-sensitivity Cardiac TRoponin I and T ASsays Trial

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-09

Start Date:

2017-11-06

Completion:

2022-12-31

Conditions

• Acute Myocardial Infarction
• Acute Coronary Syndrome

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03207867 | TERMINATED | PHASE2

315 participants

A Phase 2 Study of NIR178 in Combination With PDR001 in Patients With Solid Tumors and Non-Hodgkin Lymphoma

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2017-08-28

Completion:

2023-02-13

Conditions

• NSCLC, Non Small Cell Lung Cancer
• RCC, Renal Cell Cancer
• Pancreatic Cancer
• Urothelial Cancer
• Head and Neck Cancer
• DLBCL, Diffused Large B Cell Lymphoma
• MSS, Microsatellite Stable Colon Cancer
• TNBC, Triple Negative Breast Cancer
• Melanoma
• mCRPC, Metastatic Castration Resistant Prostate Cancer

Interventions

• DRUG

Results Available

NCT03203850 | TERMINATED | PHASE2

45 participants

Study to Evaluate the Efficacy and Safety of Deferasirox Film-coated Tablet Versus Phlebotomy in Patients With Hereditary Hemochromatosis (HH)

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2018-01-11

Completion:

2023-04-17

Conditions

• Hereditary Hemochromatosis

Interventions

• DRUG
• PROCEDURE

Results Available

NCT03201445 | TERMINATED | PHASE2

139 participants

Study to Evaluate the Testicular Safety of Filgotinib in Adult Males With Moderately to Severely Active Inflammatory Bowel Disease

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2017-07-11

Completion:

2020-11-20

Conditions

• Inflammatory Bowel Disease

Interventions

• DRUG

Results Available

NCT03167983 | COMPLETED

43 participants

Microbiome and Dementia

Study Type:

OBSERVATIONAL

Last Updated:

2024-10-09

Start Date:

2017-07-07

Completion:

2018-07-02

Conditions

• Dementia

No Results Yet

NCT03080129 | RECRUITING | NA

120 participants

Microbiome and Sarcopenia in Patients With Liver Cirrhosis

Study Type:

INTERVENTIONAL

Last Updated:

2024-10-09

Start Date:

2017-04-11

Completion:

2026-12-31

Conditions

• Sarcopenia
• Liver Cirrhosis

Interventions

• DIETARY_SUPPLEMENT

No Results Yet