Clinical Trials Updated in 2024

NCT04598451 | COMPLETED | PHASE3

222 participants

A Study to Assess the Efficacy and Safety of a Subcutaneous Formulation of Efgartigimod PH20 SC in Adults With Pemphigus (Vulgaris or Foliaceus)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-12-01
Completion:: 2023-08-22

Conditions

Pemphigus Vulgaris
Pemphigus Foliaceus

Interventions

BIOLOGICAL
OTHER
DRUG

Results Available

NCT04579445 | COMPLETED

2408 participants

Setting a Benchmark for Resource Utilization and Quality of Care in Patients Undergoing TAVI in Europe

Study Type:: OBSERVATIONAL
Last Updated:: 2024-10-01
Start Date:: 2021-05-03
Completion:: 2023-04-30

Conditions

Transcatheter Aortic Valve Implantation (TAVI)

Interventions

OTHER

No Results Yet

NCT04567368 | ACTIVE_NOT_RECRUITING

753 participants

TB-CAPT MTB/XDR Study

Study Type:: OBSERVATIONAL
Last Updated:: 2024-10-01
Start Date:: 2021-05-14
Completion:: 2024-12-30

Conditions

Tuberculosis
Resistance Bacterial
Diagnoses Disease

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04564378 | COMPLETED

43 participants

Association Between Fuchs' Endothelial Corneal Dystrophy Severity and Estrogen Exposure

Study Type:: OBSERVATIONAL
Last Updated:: 2024-10-01
Start Date:: 2018-01-17
Completion:: 2023-04-27

Conditions

Fuchs Dystrophy

Interventions

OTHER

No Results Yet

NCT04563533 | COMPLETED | PHASE1/PHASE2

580 participants

Clinical Trial of Quadrivalent Recombinant Norovirus Vaccine (Pichia Pastoris)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-08-05
Completion:: 2024-09-29

Conditions

Acute Gastroenteritis

Interventions

BIOLOGICAL

No Results Yet

NCT04521621 | TERMINATED | PHASE1/PHASE2

76 participants

A Study of Gebasaxturev (V937) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Solid Tumors (V937-013)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-10-28
Completion:: 2023-07-25

Conditions

Neoplasm Metastasis

Interventions

BIOLOGICAL
DRUG

Results Available

NCT04482595 | ACTIVE_NOT_RECRUITING | PHASE2

50 participants

BIO 300 Oral Suspension in Previously Hospitalized Long COVID Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-11-11
Completion:: 2024-07-31

Conditions

COVID-19
Long COVID
Pulmonary Fibrosis
Post-acute Respiratory Complications of COVID-19

Interventions

DRUG

No Results Yet

NCT04481230 | COMPLETED | EARLY_PHASE1

6 participants

Assessment of 99mTc-NTP 15-5 Uptake on Cartilage, a New Proteoglycan Tracer

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-11-12
Completion:: 2022-07-28

Conditions

Osteoarthritis, Knee
Breast Cancer

Interventions

DRUG

No Results Yet

NCT04480671 | COMPLETED | NA

94 participants

Impact of Level III Support Procedure on Enlarged Genital Hiatus After Minimally Invasive Sacrocolpopexy

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-08-26
Completion:: 2023-02-02

Conditions

Pelvic Organ Prolapse

Interventions

PROCEDURE
OTHER

No Results Yet

NCT04471233 | COMPLETED | NA

250 participants

Influence of Patient Sex on Pain Control and Multimodal Analgesia in Total Knee Arthroplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-12-09
Completion:: 2023-06-20

Conditions

Knee Osteoarthritis
Pain, Postoperative

Interventions

OTHER

No Results Yet

NCT04416737 | COMPLETED | PHASE1

16 participants

Evaluating the Benefits of Physiologic Insulin Delivery

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2021-11-01
Completion:: 2023-06-02

Conditions

Type 1 Diabetes

Interventions

DRUG

Results Available

NCT04360174 | COMPLETED | PHASE1

19 participants

CLN-0045: Safety, and Efficacy of OTX-TIC in Participants With Open Angle Glaucoma or Ocular Hypertension

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2018-04-25
Completion:: 2021-05-24

Conditions

Ocular Hypertension
Open Angle Glaucoma

Interventions

DRUG

Results Available

NCT04325698 | TERMINATED | PHASE3

8 participants

A BRIDGING STUDY OF PF-06439535 (CN) PLUS PACLITAXEL-CARBOPLATIN VERSUS BEVACIZUMAB PLUS PACLITAXEL-CARBOPLATIN IN NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-06-11
Completion:: 2021-05-10

Conditions

Advanced Non-squamous NSCLC

Interventions

DRUG

Results Available

NCT04265599 | RECRUITING

200 participants

Exploring Pathogenesis and Treatment of Hypercalcemia Caused by Intramuscular Injection of Paraffinoil

Study Type:: OBSERVATIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-04-30
Completion:: 2027-01-31

Conditions

Hypercalcemia
Renal Injury
Paraffinoma

No Results Yet

NCT04258969 | WITHDRAWN | NA

0 participants

Pedaling at a Low-Moderate Intensity During Chemotherapy Administration

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-01-11
Completion:: 2021-10-14

Conditions

Colorectal Cancer
Exercise, Aerobic
Chemotherapy
Chemotherapeutic Toxicity

Interventions

BEHAVIORAL

No Results Yet

NCT04238143 | RECRUITING | NA

100 participants

Adipose-Derived Biocellular Regenerative Therapy for Osteoarthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-01-10
Completion:: 2026-09-30

Conditions

Osteoarthritis
Osteo Arthritis Knee
Osteo Arthritis Shoulders
Osteoarthritis of Multiple Joints
Osteoarthritis, Hip
Osteoarthritis - Ankle/Foot

Interventions

PROCEDURE
BIOLOGICAL
DRUG

No Results Yet

NCT04216589 | COMPLETED | PHASE2

51 participants

Study of Semaglutide for Non-Alcoholic Fatty Liver Disease (NAFLD), a Metabolic Syndrome With Insulin Resistance, Increased Hepatic Lipids, and Increased Cardiovascular Disease Risk (The SLIM LIVER Study)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2021-02-19
Completion:: 2023-03-16

Conditions

HIV Infections
Non-Alcoholic Fatty Liver Disease

Interventions

DRUG

Results Available

NCT04202913 | COMPLETED | NA

867 participants

Building Resilience for Healthy Kids

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-01-12
Completion:: 2021-05-31

Conditions

Mental Health Wellness 1

Interventions

BEHAVIORAL

No Results Yet

NCT04194320 | COMPLETED | NA

45 participants

Dexamethasone Versus Nalbuphine as Adjuvants in Brachial Plexus Block

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-12-01
Completion:: 2020-05-05

Conditions

Anesthesia

Interventions

PROCEDURE

No Results Yet

NCT04144036 | COMPLETED | PHASE1

12 participants

Neihulizumab for Standard-Risk Acute Graft Versus Host Disease (GVHD)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-12-14
Completion:: 2023-04-20

Conditions

Graft-versus-host Disease

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT04114357 | COMPLETED | PHASE1

12 participants

Effect of Prebiotics on the Gut Microbiome Profile and Beta Cell Function

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-06-22
Completion:: 2023-06-09

Conditions

Type 1 Diabetes

Interventions

DRUG

Results Available

NCT04086212 | WITHDRAWN | PHASE2

0 participants

Ultrafiltration Efficacy of a PD Solution Containing Icodextrin-Xylitol-Carnitine

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-10-02
Completion:: 2022-12-31

Conditions

End Stage Renal Disease (ESRD)

Interventions

DRUG

No Results Yet

NCT04076423 | COMPLETED | PHASE4

141 participants

A Phase IV Study to Assess the Impact of the Change of Antiretroviral Treatment From Dual Therapy to Triple Therapy on Inflammation in Patients With HIV Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-10-10
Completion:: 2023-06-15

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT04066296 | RECRUITING | PHASE2

100 participants

Outcomes for Lumbar Decompressions With Use of Liposomal Bupivicaine

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-09-08
Completion:: 2024-12-31

Conditions

Lumbar Spinal Stenosis

Interventions

DRUG

No Results Yet

NCT04042922 | ACTIVE_NOT_RECRUITING | NA

80 participants

High Frequency Light and Sound Stimulation to Improve Brain Functions in Alzheimer's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-04-19
Completion:: 2026-04-30

Conditions

Alzheimer Disease

Interventions

DEVICE

No Results Yet

NCT04021121 | COMPLETED | PHASE2

40 participants

Adjunctive Linezolid for the Treatment of Tuberculous Meningitis

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2021-05-05
Completion:: 2023-07-05

Conditions

Tuberculosis, Meningeal

Interventions

DRUG

Results Available

NCT04017832 | COMPLETED | PHASE3

1441 participants

A Research Study Comparing a New Medicine Oral Semaglutide to Sitagliptin in People With Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-07-29
Completion:: 2021-10-27

Conditions

Diabetes Mellitus, Type 2

Interventions

DRUG

Results Available

NCT04010526 | RECRUITING | PHASE2

84 participants

Evaluation of Local Co-administration of Autologous ADIpose Derived Stromal Vascular Fraction With Microfat for Refractory Perianal CROHN's Fistulas.

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2020-02-19
Completion:: 2028-07-31

Conditions

Crohn Disease

Interventions

COMBINATION_PRODUCT
OTHER

No Results Yet

NCT03991013 | COMPLETED | PHASE2

192 participants

Tenofovir-lamivudine-dolutegravir Combination as Second-line ART: a Randomised Controlled Trial

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-08-08
Completion:: 2022-04-26

Conditions

HIV Infections

Interventions

DRUG

Results Available

NCT03981900 | COMPLETED

314 participants

IDentification of Factors Predictive of Tofacitinib's Survival in Patient With Rheumatoid Arthritis

Study Type:: OBSERVATIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-01-04
Completion:: 2023-02-06

Conditions

Arthritis, Rheumatoid

Interventions

DRUG

Results Available

NCT03909750 | SUSPENDED | PHASE1

50 participants

Use of Autologous Stem/Stromal Cells In Chronic Lung Disorders: Obstructive (COPD) & Restrictive (RLD)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-04-10
Completion:: 2025-09-30

Conditions

COPD
Respiratory Insufficiency

Interventions

PROCEDURE

No Results Yet

NCT03875092 | COMPLETED | PHASE3

125 participants

A Study of Carboplatin-Paclitaxel/Nab-Paclitaxel Chemotherapy With or Without Pembrolizumab (MK-3475) in Adults With First Line Metastatic Squamous Non-small Cell Lung Cancer (MK-3475-407/KEYNOTE-407)-China Extension Study

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2017-04-21
Completion:: 2020-09-30

Conditions

Non-small Cell Lung Cancer

Interventions

BIOLOGICAL
DRUG

Results Available

NCT03863704 | COMPLETED | NA

30 participants

Transcutaneous VNS to Treat Pediatric IBD

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-02-14
Completion:: 2022-12-31

Conditions

Crohn Disease
Ulcerative Colitis

Interventions

DEVICE

No Results Yet

NCT03843424 | COMPLETED | NA

1460 participants

Treatment Efforts Addressing Child Weight Management by Unifying Patients, Parents & Providers

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-09-12
Completion:: 2024-06-26

Conditions

Obesity, Childhood
Pediatric Obesity
Childhood Obesity
Adolescent Obesity
Overweight
Overweight and Obesity
Overweight or Obesity
Overweight Adolescents
Weight Gain
Overnutrition
Body Weight
Body Weight Changes
Nutrition Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT03832790 | COMPLETED

23 participants

Sleep, Glycemic Control, and Insulin Resistance in Adolescents With Type 1 Diabetes

Study Type:: OBSERVATIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-12-04
Completion:: 2023-05-31

Conditions

Type1diabetes
Adolescent Behavior
Sleep

Interventions

OTHER

No Results Yet

NCT03814512 | COMPLETED | NA

10 participants

Improving Insulin Resistance and Energy Metabolism Through Sleep Extension in Adolescents

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-03-21
Completion:: 2022-04-20

Conditions

Sleep
Diabetes Mellitus, Type 2

Interventions

BEHAVIORAL

No Results Yet

NCT03782298 | COMPLETED

140 participants

Safety and Performance of PEEK Anchors in Extremities

Study Type:: OBSERVATIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-03-12
Completion:: 2019-10-10

Conditions

Medial or Lateral Instability Repairs/Reconstructions
Hallux Valgus Repairs
Achilles Tendon Repairs/Reconstructions
Midfoot Reconstructions
Metatarsal Ligament/Tendon Repairs/Reconstructions
Bunionectomy
Scapholunate Ligament Reconstructions
Ulnar
Lateral Epicondylitis Repair
Bicep Tendon Reattachments

Interventions

DEVICE

Results Available

NCT03701698 | TERMINATED | PHASE2

1 participants

Ruxolitinib and Steroid As First Line Therapy for Acute GVHD

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2018-11-01
Completion:: 2024-09-20

Conditions

Acute GVHD

Interventions

DRUG

No Results Yet

NCT03692325 | COMPLETED | PHASE2

33 participants

Safety and Efficacy of Nivolumab in Treating Oral Proliferative Verrucous Leukoplakia

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2018-12-05
Completion:: 2022-09-01

Conditions

Leukoplakia, Oral

Interventions

DRUG

Results Available

NCT03671109 | COMPLETED | PHASE3

666 participants

Improving Maternal heAlth by Reducing Malaria in African HIV Women

Study Type:: INTERVENTIONAL
Last Updated:: 2024-10-01
Start Date:: 2019-09-18
Completion:: 2022-07-19

Conditions

Malaria
HIV/AIDS
Pregnancy Related

Interventions

DRUG

No Results Yet