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Sleep, Glycemic Control, and Insulin Resistance in Adolescents With Type 1 Diabetes

NCT03832790 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 23

Last updated 2024-10-01

No results posted yet for this study

Summary

Despite advancements in care, most adolescents with T1D have higher BMI and significantly higher HbA1c than recommended and are markedly IR, placing them at increased risk for CVD1,2. Thus, alternative approaches to improve and maintain glycemic control, IR, and BMI for adolescents with T1D are urgently needed. This proposal moves beyond the current insulin and carbohydrate counting-focused lifestyle change paradigm to focus on sleep and circadian misalignment, which will allow for identification of new mechanisms that can be directly translated into future intervention and prevention trials. The goal of the current study is to utilize multiple objective measures of sleep duration, timing (actigraphy), and circadian rhythm (melatonin) in adolescents with type 1 diabetes (T1D; N = 40) and examine relationships with glycemic control, IR, vascular health, and BMI. Further, qualitative methodology will be used to identify barriers and facilitators to healthy sleep in adolescents with T1D.

Conditions

  • Type1diabetes
  • Adolescent Behavior
  • Sleep

Interventions

OTHER

observation

observation

Sponsors & Collaborators

  • Juvenile Diabetes Research Foundation

    collaborator OTHER

  • Colorado Clinical & Translational Sciences Institute

    collaborator UNKNOWN

  • Ludeman Family Center for Women's Health Research

    collaborator UNKNOWN

  • University of Colorado, Denver

    lead OTHER

Eligibility

Min Age
14 Years
Max Age
19 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-12-04
Primary Completion
2023-05-31
Completion
2023-06-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03832790 on ClinicalTrials.gov