Clinical Trials

NCT04275323 | COMPLETED | PHASE3

302 participants

Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia (NL003-CLI-III-1)

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2019-08-02

Completion:

2024-06-03

Conditions

• Arterial Occlusive Disease
• Ischemia
• Ulcers
• Peripheral Vascular Disease

Interventions

• GENETIC
• OTHER

No Results Yet

NCT04272242 | TERMINATED | PHASE2

37 participants

Drug-Drug Interactions Between Rifapentine and Dolutegravir in HIV/LTBI Co-Infected Individuals

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2021-02-27

Completion:

2021-12-15

Conditions

• HIV Infection
• LTBI

Interventions

• DRUG
• DIETARY_SUPPLEMENT

Results Available

NCT04268641 | COMPLETED | NA

24 participants

Evaluation of Positioning Protocols on a Wheelchair in Hemiplegic Patients

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2020-08-28

Completion:

2023-12-11

Conditions

• Hemiplegia And/or Hemiparesis Following Stroke

Interventions

• OTHER

No Results Yet

NCT04249999 | WITHDRAWN | NA

0 participants

ActivOnline: Physical Activity in Cystic Fibrosis Trial UK

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2020-05-07

Completion:

2021-09-30

Conditions

• Cystic Fibrosis

Interventions

• BEHAVIORAL

No Results Yet

NCT04249245 | COMPLETED

285 participants

Role of Nasal Dysbiosis in Parkinson Disease

Study Type:

OBSERVATIONAL

Last Updated:

2024-09-19

Start Date:

2020-02-14

Completion:

2024-04-25

Conditions

• Parkinson Disease

Interventions

• OTHER

No Results Yet

NCT04247347 | COMPLETED | NA

92 participants

Tailored Health Self-Management Interventions for Highly Distressed Caregivers: Family Members of Persons With Dementia

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2019-08-29

Completion:

2022-06-21

Conditions

• Stress
• Carer Stress Syndrome
• Dementia
• Alzheimer Disease

Interventions

• BEHAVIORAL
• OTHER

Results Available

NCT04247139 | COMPLETED | NA

21 participants

Kefir Cholesterol Lowering Pilot Study

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2020-07-07

Completion:

2022-04-25

Conditions

• Hypercholesterolemia

Interventions

• OTHER

No Results Yet

NCT04245150 | COMPLETED

23 participants

Assessing the Impact of the Microbiome on Breast Cancer Radiotherapy Toxicity

Study Type:

OBSERVATIONAL

Last Updated:

2024-09-19

Start Date:

2019-03-21

Completion:

2024-07-30

Conditions

• DCIS
• Invasive Breast Cancer

Interventions

• OTHER

No Results Yet

NCT04245111 | COMPLETED

20 participants

ICG Fluorescence Imaging in Trauma Patients

Study Type:

OBSERVATIONAL

Last Updated:

2024-09-19

Start Date:

2019-05-16

Completion:

2021-11-23

Conditions

• Trauma Injury

Interventions

• OTHER

Results Available

NCT04244253 | COMPLETED | PHASE2

273 participants

A Phase 2 Trial of OPC-64005 for Major Depressive Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2020-03-03

Completion:

2022-02-08

Conditions

• Major Depressive Disorder

Interventions

• DRUG

Results Available

NCT04241471 | WITHDRAWN | NA

0 participants

Incision and Loop Drainage Utilizing a Novel Technique for Management of Cutaneous Abscess in an Adult Population

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2020-05-04

Completion:

2021-02-02

Conditions

• Abscess
• Drain Abscess

Interventions

• PROCEDURE
• DEVICE

No Results Yet

NCT04240210 | TERMINATED | PHASE4

1 participants

Integrase Regimen Switch to Symtuza to Increase Tolerability/Adherence (SYMita)

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2019-09-17

Completion:

2021-12-01

Conditions

• Human Immunodeficiency Virus

Interventions

• DRUG

No Results Yet

NCT04239898 | COMPLETED | NA

26 participants

Microgreen Consumption for Healthy Aging

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2019-07-16

Completion:

2019-11-22

Conditions

• Aging
• Menopause
• Healthy

Interventions

• OTHER

No Results Yet

NCT04237467 | COMPLETED

16 participants

Effects of Aging and Gender-Affirming Hormone Therapy on Vascular Endothelial Function and Metabolic Profiles in Transgender Men

Study Type:

OBSERVATIONAL

Last Updated:

2024-09-19

Start Date:

2020-01-29

Completion:

2023-12-31

Conditions

• Transgender
• Gender Identity
• Vascular Stiffness
• Vascular Inflammation
• Blood Pressure
• Lipid Disorder
• Appetitive Behavior

Interventions

• OTHER

No Results Yet

NCT04235140 | COMPLETED | PHASE3

52 participants

Long-term Safety of Lumacaftor/Ivacaftor in Participants With Cystic Fibrosis Who Are Homozygous for F508del and 12 to <24 Months of Age at Treatment Initiation

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2020-02-24

Completion:

2023-08-22

Conditions

• Cystic Fibrosis

Interventions

• DRUG

Results Available

NCT04232839 | TERMINATED | PHASE1

24 participants

A Study in Healthy Men to Find the Best Formulation of BI 894416 and to Test How This is Taken up in the Body

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2020-02-25

Completion:

2020-11-30

Conditions

• Healthy

Interventions

• DRUG

Results Available

NCT04231773 | COMPLETED | PHASE1/PHASE2

20 participants

The Effect of Inhaled Nitric Oxide on Maximal Oxygen Consumption During Exercise in Hypoxia

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2020-08-17

Completion:

2021-12-04

Conditions

• Hypoxia

Interventions

• DRUG

No Results Yet

NCT04223479 | COMPLETED | PHASE2/PHASE3

30 participants

Effect of Probiotic Supplementation on the Immune System in Patients With Ulcerative Colitis in Amman, Jordan

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2020-01-15

Completion:

2022-03-01

Conditions

• Ulcerative Colitis

Interventions

• DRUG

Results Available

NCT04220307 | COMPLETED | PHASE2

34 participants

A Study of a PD-1/CTLA-4 Bispecific Antibody AK104 in Patients With Metastatic Nasopharyngeal Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2020-04-26

Completion:

2021-05-15

Conditions

• Nasopharyngeal Carcinoma

Interventions

• BIOLOGICAL

No Results Yet

NCT04218526 | COMPLETED | NA

5 participants

Deep Brain Stimulation of the Cuneiform Nucleus for Levodopa-resistant Freezing of Gait in Parkinson's Disease

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2020-04-27

Completion:

2024-09-12

Conditions

• Parkinson Disease

Interventions

• DEVICE

No Results Yet

NCT04218240 | COMPLETED | PHASE2

90 participants

Combining Pregabalin (LYRICA®) With Lofexidine (LUCEMYRATM) to Treat OPIOID Withdrawal

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2020-12-17

Completion:

2023-08-31

Conditions

• Opioid Withdrawal

Interventions

• DRUG

Results Available

NCT04211753 | RECRUITING | NA

80 participants

Effectiveness and Security Testing of a Mobile App (B·RIGHT) for Emotional Crisis in Borderline Personality Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2025-02-28

Completion:

2025-03-31

Conditions

• Borderline Personality Disorder

Interventions

• BEHAVIORAL
• DEVICE

No Results Yet

NCT04210986 | COMPLETED | PHASE1/PHASE2

75 participants

Senolytic Drugs Attenuate Osteoarthritis-Related Articular Cartilage Degeneration: A Clinical Trial

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2020-01-06

Completion:

2023-01-05

Conditions

• Osteoarthritis, Knee

Interventions

• DIETARY_SUPPLEMENT
• DRUG

Results Available

NCT04210648 | NOT_YET_RECRUITING | NA

80 participants

Effectiveness and Security Testing of a Mobile App for Self-Managing Emotion Dysregulation

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2026-09-30

Completion:

2027-06-30

Conditions

• Emotional Dysregulation

Interventions

• DEVICE

No Results Yet

NCT04205227 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

137 participants

ENB003 Plus Pembrolizumab Phase 1b/2a in Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2020-02-18

Completion:

2026-01-01

Conditions

• Cancer
• Melanoma
• Ovary Cancer
• Pancreatic Cancer
• Solid Tumor

Interventions

• DRUG

No Results Yet

NCT04204447 | COMPLETED | NA

176 participants

Hepatitis C-Video vs. Brochure Education Delivery

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2019-11-27

Completion:

2020-10-31

Conditions

• Hepatitis C

Interventions

• OTHER

Results Available

NCT04199351 | TERMINATED | PHASE1

60 participants

Single and Multiple Ascending Dose Study of AMG 171 in Subjects With Obesity

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2019-12-13

Completion:

2021-09-10

Conditions

• Obesity

Interventions

• DRUG

Results Available

NCT04197700 | COMPLETED | NA

600 participants

The PRESSURE CABG Cardiac Surgery Trial

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2022-11-01

Completion:

2024-05-01

Conditions

• Coronary Artery Bypass Grafting
• Hypotension

Interventions

• OTHER

No Results Yet

NCT04196777 | COMPLETED | NA

525 participants

Audit-and-feedback to Improve Antimicrobial-prescribing Among Urologists

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2022-08-01

Completion:

2023-07-31

Conditions

• Urologic Diseases
• Antibacterial Drug Adverse Reaction

Interventions

• BEHAVIORAL

Results Available

NCT04192565 | COMPLETED | NA

10 participants

A Prospective Investigation of the ColubrisMX ELS System

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2020-09-13

Completion:

2021-04-15

Conditions

• Colorectal Neoplasms
• Colorectal Polyp
• Colorectal Adenoma
• Colorectal Adenomatous Polyp

Interventions

• DEVICE

No Results Yet

NCT04191538 | COMPLETED | PHASE1/PHASE2

56 participants

Conditioning Electrical Stimulation to Improve Outcomes in Carpal Tunnel Syndrome

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2020-01-01

Completion:

2024-04-19

Conditions

• Carpal Tunnel Syndrome

Interventions

• PROCEDURE

No Results Yet

NCT04188743 | RECRUITING | PHASE2/PHASE3

150 participants

Decolonization of Gram-negative Multi-resistant Organisms (MDRO) with Donor Microbiota (FMT)

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2019-12-18

Completion:

2025-12-30

Conditions

• Resistance Bacterial

Interventions

• BIOLOGICAL

No Results Yet

NCT04187898 | COMPLETED | PHASE1

59 participants

Open-Label, Phase 1 Study to Evaluate Duration of Severe Neutropenia After Same-Day Dosing of Eflapegrastim in Patients With Breast-Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2020-03-11

Completion:

2024-07-16

Conditions

• Neutropenia
• Breast Cancer

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT04186429 | COMPLETED

401 participants

Epigenetic Effects on Traumatic Brain Injury Recovery

Study Type:

OBSERVATIONAL

Last Updated:

2024-09-19

Start Date:

2017-07-01

Completion:

2024-08-31

Conditions

• Traumatic Brain Injury
• Orthopedic Injury

No Results Yet

NCT04182516 | TERMINATED | PHASE1

52 participants

Study of NMS-03305293 in Pts with Selected Advanced/Metastatic Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2019-11-25

Completion:

2023-03-31

Conditions

• Advanced/Metastatic Solid Tumors

Interventions

• DRUG

No Results Yet

NCT04181359 | WITHDRAWN | PHASE1/PHASE2

0 participants

The Effect of Inhaled Nitric Oxide on Dyspnea and Exercise Tolerance in Interstitial Lung Disease.

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2024-09-01

Completion:

2025-12-01

Conditions

• Dyspnea

Interventions

• DRUG

No Results Yet

NCT04179097 | TERMINATED

15 participants

Photoplethysmographic Dichrotic Notch Reflexes Systemic Hemodynamics

Study Type:

OBSERVATIONAL

Last Updated:

2024-09-19

Start Date:

2019-11-05

Completion:

2024-08-01

Conditions

• Vascular Diseases

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT04171960 | COMPLETED

1106 participants

Clinical Evaluation of the i-STAT TBI Test

Study Type:

OBSERVATIONAL

Last Updated:

2024-09-19

Start Date:

2020-07-31

Completion:

2023-06-26

Conditions

• Traumatic Brain Injury

Interventions

• DIAGNOSTIC_TEST
• OTHER

No Results Yet

NCT04167657 | COMPLETED | PHASE2

14 participants

SinTilimab After Radiation (STAR Study)

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2019-04-15

Completion:

2023-11-30

Conditions

• Carcinoma, Non-Small Cell Lung

Interventions

• DRUG

No Results Yet

NCT04166006 | RECRUITING | PHASE2

51 participants

A Phase II Study on Adjuvant Vaccination with Dendritic Cells Loaded with Autologous Tumor Homogenate in Resected Stage IV Rare Cancers.

Study Type:

INTERVENTIONAL

Last Updated:

2024-09-19

Start Date:

2019-12-12

Completion:

2027-04-30

Conditions

• Head Neck Tumors
• Neuroendocrine Tumors
• Soft Tissue Sarcoma
• Rare Cancer
• Vaccination

Interventions

• BIOLOGICAL
• DRUG

No Results Yet