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Role of Nasal Dysbiosis in Parkinson Disease

NCT04249245 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 285

Last updated 2024-09-19

No results posted yet for this study

Summary

Olfactory dysfunction is frequent in Parkinson Disease (PD) and may be present years before the motor symptoms appear. The early olfactory dysfunction could result from environmental factors acting through the nasal cavity such as microbial communities. In across-sectional bicentric study, groups of 160 PD patients and 160 controls will be compared for nasal microbiota composition according to their geographical origin. We will search an association between microbiota and the presence of an olfactory deficit, cognitive deficit and thymic disorder.

Conditions

  • Parkinson Disease

Interventions

OTHER

Nasal Swab

All

Sponsors & Collaborators

  • Institut Pasteur

    lead INDUSTRY

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-02-14
Primary Completion
2024-04-25
Completion
2024-04-25

Countries

  • France
  • Guadeloupe

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04249245 on ClinicalTrials.gov