Clinical Trials Updated in 2024

NCT04534283 | TERMINATED | PHASE2

16 participants

A Basket Trial of an ERK1/2 Inhibitor (LY3214996) in Combination With Abemaciclib.

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2020-10-05
Completion:: 2023-08-07

Conditions

Cancer
Cancer Metastatic
BRAF V600E
MEK1 Gene Mutation
MEK2 Gene Mutation
ERK Mutation
RAF1 Gene Mutation

Interventions

DRUG

Results Available

NCT04528719 | COMPLETED | PHASE1

651 participants

A Dose Escalation Study to Evaluate Safety, Reactogenicity, and Immunogenicity of mRNA-1345 in Healthy Adults and in Children Who Are Respiratory Syncytial Virus (RSV)-Seropositive

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2020-09-30
Completion:: 2024-07-18

Conditions

Respiratory Syncytial Virus

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT04493151 | COMPLETED | PHASE1

8 participants

Imipenem/Cilastatin/Relebactam PK in ECMO

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2021-01-01
Completion:: 2023-05-31

Conditions

Sepsis

Interventions

DRUG

Results Available

NCT04461548 | COMPLETED | NA

181 participants

Micro-interventions Aiming to Optimize Expectations or Self-compassion to Improve Well-being/Reduce Stress and Their Differential Effects

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2020-06-06
Completion:: 2020-10-19

Conditions

no Specific Clincal Condition Required (Focus is on Persons Who Are Feeling Stressed or Want to Improve Their Wellbeing)

Interventions

BEHAVIORAL

No Results Yet

NCT04445766 | COMPLETED

115 participants

Efficacy and Complications of Microvascular Decompression

Study Type:: OBSERVATIONAL
Last Updated:: 2024-08-07
Start Date:: 2012-05-01
Completion:: 2020-10-31

Conditions

Trigeminal Neuralgia

No Results Yet

NCT04316845 | COMPLETED | NA

38 participants

18F-fluorocholine PET/CT for Hyperparathyroidism

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2018-01-16
Completion:: 2019-11-06

Conditions

Hyperparathyroidism

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04296890 | COMPLETED | PHASE3

106 participants

A Study of Mirvetuximab Soravtansine in Platinum-Resistant, Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2020-07-23
Completion:: 2021-11-16

Conditions

Epithelial Ovarian Cancer
Peritoneal Cancer
Fallopian Tube Cancer

Interventions

DRUG

Results Available

NCT04286685 | RECRUITING

1600 participants

Development of a New Prognostic Assessment Tool for Postoperative Myocardial Injury

Study Type:: OBSERVATIONAL
Last Updated:: 2024-08-07
Start Date:: 2020-01-07
Completion:: 2025-04-07

Conditions

Perioperative Complication
Myocardial Injury

No Results Yet

NCT04283019 | COMPLETED | PHASE1

75 participants

The Pharmacokinetic and Pharmacodynamic Effects of Oral Cannabidiol (CBD) Under Acute and Chronic Exposure Conditions

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2021-08-15
Completion:: 2024-06-17

Conditions

Cannabis, Drug Effects

Interventions

DRUG

No Results Yet

NCT04282031 | RECRUITING | PHASE1/PHASE2

224 participants

A Study of BPI-1178 in Patients With Advanced Solid Tumor and HR+/HER2- Breast Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2020-06-15
Completion:: 2024-12-31

Conditions

Advanced Solid Tumor
HR+/HER2- Breast Cancer

Interventions

DRUG

No Results Yet

NCT04254692 | TERMINATED | PHASE4

2 participants

Optimizing Recovery in Abdominoplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2021-01-05
Completion:: 2021-01-21

Conditions

Postoperative Pain

Interventions

DRUG
OTHER

Results Available

NCT04241822 | COMPLETED | NA

150 participants

Musculoskeletal Pain in Long-term Dizziness

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2020-08-15
Completion:: 2024-06-30

Conditions

Vestibular Disease
Musculoskeletal Pain
Rehabilitation

Interventions

BEHAVIORAL

No Results Yet

NCT04219098 | COMPLETED | NA

75 participants

Pain After Preoperative UltraSound Guided Hip Injections for Total Hip Arthroplasty (PUSH)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2020-02-01
Completion:: 2021-07-30

Conditions

Total Hip Replacement
Arthroplasty

Interventions

PROCEDURE
OTHER

No Results Yet

NCT04177706 | COMPLETED | PHASE2

21 participants

Ketamine for the Treatment of Opioid Use Disorder and Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2020-12-17
Completion:: 2022-11-21

Conditions

Depression
Opioid-use Disorder
Opioid Abuse

Interventions

DRUG

Results Available

NCT04098783 | COMPLETED | NA

72 participants

Health Belief Model Based Nursing Interventions on Lymphedema Prevention

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2016-05-15
Completion:: 2017-04-15

Conditions

Breast Cancer
Breast Cancer Lymphedema
Home Visit

Interventions

OTHER

No Results Yet

NCT04059939 | COMPLETED | NA

542 participants

Evidence-Based Interventions to Enhance Outcomes Among Struggling Readers

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2017-08-01
Completion:: 2022-05-31

Conditions

Reading Disability
Anxiety

Interventions

OTHER
BEHAVIORAL

No Results Yet

NCT04052763 | TERMINATED

164 participants

FFR-CT to Detect the Absence of Hemodynamically Significant Lesions in Patients With High-risk Acute Coronary Syndrome

Study Type:: OBSERVATIONAL
Last Updated:: 2024-08-07
Start Date:: 2019-08-28
Completion:: 2022-04-01

Conditions

Acute Coronary Syndrome

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04048668 | WITHDRAWN | NA

0 participants

tDCS to Treat Subacute Aphasia

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2019-09-01
Completion:: 2022-07-15

Conditions

Aphasia
Stroke, Acute

Interventions

DEVICE

No Results Yet

NCT03983291 | RECRUITING | NA

40 participants

FaReWell Depression - Facial Exercise Program to Treat Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2019-06-01
Completion:: 2025-03-01

Conditions

Depression

Interventions

BEHAVIORAL

No Results Yet

NCT03948893 | RECRUITING | NA

200 participants

Smoking Cessation Behavioral Treatment Study

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2019-12-19
Completion:: 2025-03-31

Conditions

Tobacco Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT03931941 | COMPLETED | PHASE3

793 participants

Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection (PUNCH CD3-OLS)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2019-07-30
Completion:: 2023-07-21

Conditions

Clostridium Difficile Infection
Infection
Communicable Diseases

Interventions

DRUG

Results Available

NCT03923582 | COMPLETED | NA

412 participants

Training for Health Professionals In Tanzania

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2021-05-01
Completion:: 2021-09-07

Conditions

Health Knowledge, Attitudes, Practice
Training

Interventions

BEHAVIORAL

Results Available

NCT03902080 | COMPLETED | PHASE3

1105 participants

Study to Evaluate the Efficacy, Safety and Tolerability of Vibegron in Men With Overactive Bladder (OAB) Symptoms on Pharmacological Therapy for Benign Prostatic Hyperplasia (BPH)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2019-03-26
Completion:: 2023-06-15

Conditions

Overactive Bladder

Interventions

DRUG

Results Available

NCT03896425 | COMPLETED | NA

73 participants

Maximizing the Impact of Neuroplasticity Using Transcranial Electrical Stimulation Study 1

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2019-04-01
Completion:: 2023-05-30

Conditions

Transcranial Direct Current Stimulation
Healthy

Interventions

DEVICE

Results Available

NCT03866499 | ACTIVE_NOT_RECRUITING | PHASE3

369 participants

A Study of BPI-7711 Capsule in Non-small Cell Lung Cancer Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2021-04-30
Completion:: 2023-11-30

Conditions

NSCLC

Interventions

DRUG

No Results Yet

NCT03800394 | COMPLETED

52 participants

Pharmacokinetics of Intracellular TFV-DP and FTC-TP in HIV-infected Adolescents

Study Type:: OBSERVATIONAL
Last Updated:: 2024-08-07
Start Date:: 2019-01-28
Completion:: 2024-05-31

Conditions

Human Immunodeficiency Virus (HIV)
Tuberculosis
Coinfection

Interventions

OTHER

No Results Yet

NCT03797677 | COMPLETED | NA

10 participants

MN4000 for Treatment of CF and MND Patients in the Home Setting

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2017-03-09
Completion:: 2017-11-30

Conditions

Cystic Fibrosis
Motor Neuron Disease
Airway Clearance Impairment

Interventions

DEVICE

Results Available

NCT03424174 | ACTIVE_NOT_RECRUITING | NA

80 participants

Clinical Outcome and Cytokine Expression After TKA

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2017-01-04
Completion:: 2023-12-31

Conditions

Osteoarthritis

Interventions

DEVICE

No Results Yet

NCT03417895 | COMPLETED | PHASE2

59 participants

SHR-1210 Combined With Apatinib in Treatment of ED-SCLC After Failure of First Line Standard Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2018-04-20
Completion:: 2021-08-04

Conditions

Small-cell Lung Cancer

Interventions

DRUG

Results Available

NCT03399331 | COMPLETED | PHASE1

45 participants

Honey or Olive Oil for Treating Oral Mucositis in Children and Adults With Leukemia Receiving Intensive Chemotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2017-07-10
Completion:: 2021-12-01

Conditions

Oral Mucositis
Leukemia

Interventions

DIETARY_SUPPLEMENT
COMBINATION_PRODUCT

No Results Yet

NCT03340818 | COMPLETED | NA

66 participants

Bone Marrow Concentrate Intradiscal Injection for Chronic Discogenic Low Back Pain

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2018-08-01
Completion:: 2024-08-07

Conditions

Discogenic Pain

Interventions

OTHER

No Results Yet

NCT03327064 | WITHDRAWN | PHASE1/PHASE2

0 participants

A Biomarker Evaluation Trial of UAB30 in Renal Transplant Recipients at High Risk for Non-melanoma Skin Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2020-10-01
Completion:: 2023-08-31

Conditions

Non-melanoma Skin Cancer

Interventions

DRUG

No Results Yet

NCT03275636 | COMPLETED | PHASE2/PHASE3

98 participants

Haploidentical Donor vs mMUD in Hematological Malignancies

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2018-01-01
Completion:: 2024-04-13

Conditions

AML
ALL
MDS

Interventions

BIOLOGICAL

No Results Yet

NCT03221374 | COMPLETED | NA

231 participants

Mind-body Awareness Training and Brain-computer Interface

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2016-09-01
Completion:: 2023-05-31

Conditions

Healthy Subjects

Interventions

BEHAVIORAL

Results Available

NCT03206177 | COMPLETED | PHASE1

26 participants

Paclitaxel/Carboplatin + Galunisertib for Patients With Carcinosarcoma of the Uterus or Ovary

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2017-08-23
Completion:: 2021-07-28

Conditions

Carcinosarcoma, Ovarian

Interventions

DRUG

Results Available

NCT03192345 | COMPLETED | PHASE1

161 participants

A First-in-human Study of the Safety, Pharmacokinetics, Pharmacodynamics and Anti-tumor Activity of SAR439459 Monotherapy and Combination of SAR439459 and Cemiplimab in Patients With Advanced Solid Tumors

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2017-06-09
Completion:: 2021-12-21

Conditions

Malignant Solid Tumor

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT03190265 | COMPLETED | PHASE2

61 participants

Study of CRS-207, Nivolumab, and Ipilimumab With or Without GVAX Pancreas Vaccine (With Cy) in Patients With Pancreatic Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2017-12-14
Completion:: 2022-08-03

Conditions

Pancreatic Cancer

Interventions

DRUG

Results Available

NCT03133286 | COMPLETED

16 participants

Radiotherapy Assessments During Intervention ANd Treatment (RADIANT)

Study Type:: OBSERVATIONAL
Last Updated:: 2024-08-07
Start Date:: 2017-04-06
Completion:: 2020-02-24

Conditions

Radiation Therapy
Cancer
Cancer of Anus
Cancer of Bladder
Cancer of Cervix
Cancer of Colon
Cancer of Rectum
Cancer of Esophagus
Cancer of Gallbladder
Cancer of Liver
Cancer of Ovary
Cancer of Pancreas
Cancer of Prostate
Cancer of Kidney and Renal Pelvis
Cancer of Stomach
Cancer of Testis
Cancer of Uterus
Cancer of Uterus and Cervix
Cancer of Kidney

No Results Yet

NCT03068598 | COMPLETED | NA

29 participants

Suicide Sleep Monitoring (Ssleem)

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2017-03-08
Completion:: 2019-03-06

Conditions

Suicide, Attempted

Interventions

DEVICE

No Results Yet

NCT03017586 | COMPLETED | NA

72 participants

Efficacy and Safety of DBS in Patients With Primary Dystonia

Study Type:: INTERVENTIONAL
Last Updated:: 2024-08-07
Start Date:: 2017-12-27
Completion:: 2020-09-13

Conditions

Dystonia

Interventions

DEVICE

No Results Yet