Clinical Trials

NCT04425629 | TERMINATED | PHASE3

10078 participants

Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for the Treatment of Ambulatory Adult and Pediatric Patients With COVID-19

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2020-06-16

Completion:

2022-01-21

Conditions

• COVID-19

Interventions

• DRUG

Results Available

NCT04417218 | COMPLETED | NA

67 participants

Determinants of Alpha-aminoadipic Acid (2-AAA) and Relationship to Diabetes: Study 2

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2020-08-17

Completion:

2023-01-01

Conditions

• Healthy

Interventions

• DIETARY_SUPPLEMENT

Results Available

NCT04342000 | WITHDRAWN | NA

0 participants

The Effect of Movement Education on Jumping/Landing Quality in High School Athletes

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2019-10-28

Completion:

2023-08-15

Conditions

• ACL Injury

Interventions

• OTHER

No Results Yet

NCT04267939 | TERMINATED | PHASE1

14 participants

ATR Inhibitor Elimusertib (BAY1895344) Plus Niraparib Phase 1b Study in Advanced Solid Tumors and Ovarian Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2020-02-26

Completion:

2023-12-01

Conditions

• Advanced Solid Tumors (Excluding Prostate Cancer)
• Ovarian Cancer

Interventions

• DRUG

No Results Yet

NCT04232267 | COMPLETED

329 participants

Analysis of Sleep Study Data to Assess Depressive Burden

Study Type:

OBSERVATIONAL

Last Updated:

2023-12-21

Start Date:

2020-01-13

Completion:

2022-03-01

Conditions

• Sleep Disorder
• Depressive; Behavioral Disorder
• Mood Disorders

Interventions

• DEVICE

No Results Yet

NCT04209842 | NOT_YET_RECRUITING | NA

20 participants

Effectiveness Gastric Balloon in Obese Adolescents

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2024-09-30

Completion:

2026-08-31

Conditions

• Obesity, Morbid

Interventions

• DEVICE

No Results Yet

NCT04134767 | COMPLETED | NA

234 participants

Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE)

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2019-11-15

Completion:

2022-10-27

Conditions

• Substance Use
• HIV Infections
• HCV Infection
• Sexually Transmitted Infections (Not HIV or Hepatitis)
• Overdose, Drug
• Opioid Use

Interventions

• BEHAVIORAL

Results Available

NCT04115345 | COMPLETED | PHASE1

6 participants

A Study of a Renal Autologous Cell Therapy (REACT) in Patients With Chronic Kidney Disease (CKD) From Congenital Anomalies of the Kidney and Urinary Tract (CAKUT).

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2019-08-13

Completion:

2023-01-31

Conditions

• Chronic Kidney Disease
• Congenital Anomalies of Kidney and Urinary Tract

Interventions

• BIOLOGICAL

No Results Yet

NCT04096716 | TERMINATED | PHASE1

14 participants

Mapping Draining Lymph Nodes in CNS Malignancies

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2019-12-03

Completion:

2022-04-30

Conditions

• Central Nervous System Neoplasms
• Central Nervous System Tumor

Interventions

• DRUG

No Results Yet

NCT04093427 | TERMINATED | NA

8 participants

Influence of an Inverse Pressure Ramp in Long-term Non-invasive Ventilation on Dyspnea in the Morning After Therapy

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2019-08-01

Completion:

2022-07-31

Conditions

• Noninvasive Ventilation
• Dyspnea

Interventions

• OTHER

No Results Yet

NCT04088799 | COMPLETED

10 participants

LDL-Apheresis for FSGS CardioRenal Outcomes

Study Type:

OBSERVATIONAL

Last Updated:

2023-12-21

Start Date:

2019-01-01

Completion:

2023-06-01

Conditions

• Focal Segmental Glomerulosclerosis

Interventions

• OTHER

No Results Yet

NCT04070287 | COMPLETED | EARLY_PHASE1

388 participants

Innovative Tools to Expand HIV Self-Testing

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2019-07-01

Completion:

2020-07-31

Conditions

• HIV/AIDS
• Sexually Transmitted Diseases

Interventions

• COMBINATION_PRODUCT

Results Available

NCT04031001 | COMPLETED

43 participants

Vascular No-React Graft Against Infection

Study Type:

OBSERVATIONAL

Last Updated:

2023-12-21

Start Date:

2017-12-22

Completion:

2021-02-06

Conditions

• Vascular Infections

Interventions

• DEVICE

No Results Yet

NCT03960580 | COMPLETED | PHASE3

223 participants

Study Evaluating the Efficacy and Safety of Intranasal Administration of OPN-375 in Subjects With Chronic Rhinosinusitis Without the Presence of Nasal Polyps

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2019-06-06

Completion:

2022-05-04

Conditions

• Chronic Rhinosinusitis

Interventions

• DRUG

Results Available

NCT03803202 | COMPLETED | PHASE1/PHASE2

630 participants

A Single Ascending Dose Study in Adults (Stage 1) and Single Ascending Dose-Finding Study (Stage 2) in Elderly Subjects With ASP3772, A Pneumococcal Vaccine

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2019-01-24

Completion:

2020-09-28

Conditions

• Pneumonia, Bacterial
• Healthy Volunteers
• Pneumococcal Disease

Interventions

• BIOLOGICAL

Results Available

NCT03801720 | TERMINATED | NA

4 participants

UltraWee: Ultrasound Bladder Stimulation

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2019-01-29

Completion:

2023-04-13

Conditions

• Urinalysis

Interventions

• OTHER

No Results Yet

NCT03782727 | COMPLETED

148 participants

ObservAtional Study to Investigate Surgical Site Infection in Ulcerated Skin Cancers

Study Type:

OBSERVATIONAL

Last Updated:

2023-12-21

Start Date:

2019-03-12

Completion:

2020-05-31

Conditions

• Skin Cancer

Results Available

NCT03737812 | COMPLETED | PHASE2

123 participants

A Study to Assess the Safety and Efficacy of Elezanumab When Added to Standard of Care in Progressive Forms of Multiple Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2019-02-27

Completion:

2021-01-15

Conditions

• Multiple Sclerosis (MS)

Interventions

• DRUG

Results Available

NCT03734419 | WITHDRAWN

0 participants

The Use of Aging Biomarkers in Saliva, Based on DNA Methylation Status in Elovl2 to Predict Biological Age

Study Type:

OBSERVATIONAL

Last Updated:

2023-12-21

Start Date:

2019-12-01

Completion:

2020-07-01

Conditions

• Healthy

No Results Yet

NCT03673722 | COMPLETED | NA

108 participants

Mediterranean Diet, Exercise and Dementia Risk in UK Adults

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2019-04-01

Completion:

2021-02-26

Conditions

• Dementia

Interventions

• OTHER

No Results Yet

NCT03642509 | RECRUITING | NA

750 participants

Left Atrial Appendage Occlusion Versus Novel Oral Anticoagulation for Stroke Prevention in Atrial Fibrillation

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2019-01-01

Completion:

2026-01-01

Conditions

• Atrial Fibrillation
• Stroke

Interventions

• DEVICE
• DRUG

No Results Yet

NCT03632356 | ACTIVE_NOT_RECRUITING | NA

79 participants

A Multi-Site RCT of a Stepped-Care Intervention for Emergency Department Patients With Panic Attacks and Panic Disorder

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2018-06-11

Completion:

2024-05-31

Conditions

• Panic Attacks and Disorders

Interventions

• BEHAVIORAL
• DIAGNOSTIC_TEST

No Results Yet

NCT03565367 | COMPLETED | PHASE1

9 participants

Hyperpolarized Carbon C 13 Pyruvate Magnetic Resonance Spectroscopic Imaging in Detecting Lactate and Bicarbonate in Participants With Central Nervous System Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2018-11-06

Completion:

2019-06-20

Conditions

• Malignant Central Nervous System Neoplasm
• Metastatic Malignant Neoplasm in the Central Nervous System

Interventions

• OTHER
• DRUG
• PROCEDURE

Results Available

NCT03529513 | COMPLETED

234 participants

Medibio DDA Confirmatory Performance Study

Study Type:

OBSERVATIONAL

Last Updated:

2023-12-21

Start Date:

2017-08-18

Completion:

2018-05-04

Conditions

• Major Depressive Episode

Interventions

• DIAGNOSTIC_TEST

No Results Yet

NCT03513510 | COMPLETED | NA

101 participants

Development and Pilot Testing of a Childhood Obesity Treatment Program

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2013-01-01

Completion:

2015-06-27

Conditions

• Childhood Obesity

Interventions

• BEHAVIORAL

No Results Yet

NCT03505086 | RECRUITING

1000 participants

Bleeding In Thrombocytopenia Explained

Study Type:

OBSERVATIONAL

Last Updated:

2023-12-21

Start Date:

2018-12-04

Completion:

2022-10-01

Conditions

• Hematologic Neoplasms
• Bleeding
• Hemorrhage
• Platelet Transfusion

Interventions

• DIAGNOSTIC_TEST
• OTHER

No Results Yet

NCT03480659 | TERMINATED

165 participants

Detection of Breast Cancer With Non-invasive Method Based on DNA Methylation of Circulated Tumor DNA, PBMC

Study Type:

OBSERVATIONAL

Last Updated:

2023-12-21

Start Date:

2018-06-01

Completion:

2021-08-01

Conditions

• Breast Cancer
• Breast Cancer Female

No Results Yet

NCT03454451 | COMPLETED | PHASE1

117 participants

CPI-006 Alone and in Combination With Ciforadenant and With Pembrolizumab for Patients With Advanced Cancers

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2018-04-25

Completion:

2022-12-28

Conditions

• Non-Small Cell Lung Cancer
• Renal Cell Cancer
• Colorectal Cancer
• Triple Negative Breast Cancer
• Cervical Cancer
• Ovarian Cancer
• Pancreatic Cancer
• Endometrial Cancer
• Sarcoma
• Squamous Cell Carcinoma of the Head and Neck
• Bladder Cancer
• Metastatic Castration Resistant Prostate Cancer
• Non-hodgkin Lymphoma

Interventions

• DRUG

No Results Yet

NCT03443687 | COMPLETED | NA

54 participants

Systematized Quality Exercise Alternatives for Stress Incontinence

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2018-06-01

Completion:

2020-03-03

Conditions

• Stress Urinary Incontinence
• Pelvic Floor; Weak
• Incontinence, Urinary
• Quality of Life

Interventions

• BEHAVIORAL
• DEVICE

Results Available

NCT03245320 | TERMINATED

50 participants

Clinical Evaluation of the TITAN™ Total Shoulder System

Study Type:

OBSERVATIONAL

Last Updated:

2023-12-21

Start Date:

2017-03-20

Completion:

2022-03-22

Conditions

• Arthritis
• Arthritis, Degenerative
• Rheumatoid Arthritis
• Post-traumatic Arthrosis of Other Joints, Shoulder Region
• Rotator Cuff Syndrome of Shoulder and Allied Disorders
• Fracture
• Avascular Necrosis
• Joint Instability
• Joint Trauma
• Dislocation, Shoulder
• Pain, Shoulder

Interventions

• DEVICE

No Results Yet

NCT03219268 | COMPLETED | PHASE1

277 participants

A Study of MGD013 in Patients With Unresectable or Metastatic Neoplasms

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2017-08-18

Completion:

2023-02-08

Conditions

• Advanced Solid Tumors
• Hematologic Neoplasms
• Ovarian Cancer
• HER2-positive Advanced Solid Tumors
• Non Small Cell Lung Cancer
• Small-cell Lung Cancer
• Squamous Cell Carcinoma of Head and Neck
• Cholangiocarcinoma
• Cervical Cancer
• TNBC - Triple-Negative Breast Cancer

Interventions

• BIOLOGICAL

No Results Yet

NCT03146754 | COMPLETED | NA

15 participants

A Study to Evaluate Lung Ultrasound as a Method to Measure Changes in Extravascular Lung Water Induced by Positional Changes (LUPE)

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2017-05-04

Completion:

2023-01-01

Conditions

• Acute Decompensated Heart Failure

Interventions

• OTHER

No Results Yet

NCT03071861 | COMPLETED | PHASE2

28 participants

Mild Encephalopathy in the Newborn Treated With Darbepoetin

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2017-12-01

Completion:

2019-12-01

Conditions

• Neonatal Encephalopathy
• Hypoxic-Ischemic Encephalopathy Mild

Interventions

• DRUG

Results Available

NCT03020381 | RECRUITING

600 participants

Gait as Predictor of Dementia and Falls. The Gait and Brain Cohort Study

Study Type:

OBSERVATIONAL

Last Updated:

2023-12-21

Start Date:

2007-12-31

Completion:

2033-01-31

Conditions

• Gait Apraxia
• Mild Cognitive Impairment
• Subjective Cognitive Impairment
• Cerebral Atrophy
• Alzheimer Disease
• Dementia

No Results Yet

NCT03005860 | WITHDRAWN | NA

0 participants

Effect of TIVA Propofol vs Sevoflurane Anaesthetic on Serum Biomarkers and on PBMCs in Breast Cancer Surgery

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2017-01-01

Completion:

2020-10-31

Conditions

• Female Breast Cancer

Interventions

• DRUG

No Results Yet

NCT02950337 | ACTIVE_NOT_RECRUITING | NA

41 participants

Stereotactic Body Radiation Therapy for Un-biopsied Early- Stage Non Small Cell Lung Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2015-12-31

Completion:

2023-12-31

Conditions

• Non Small Cell Lung Cancer

Interventions

• RADIATION

No Results Yet

NCT02928224 | COMPLETED | PHASE3

702 participants

Study of Encorafenib + Cetuximab Plus or Minus Binimetinib vs. Irinotecan/Cetuximab or Infusional 5-Fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab With a Safety Lead-in of Encorafenib + Binimetinib + Cetuximab in Patients With BRAF V600E-mutant Metastatic Colorectal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2016-10-13

Completion:

2019-02-11

Conditions

• BRAF V600E-mutant Metastatic Colorectal Cancer

Interventions

• DRUG

Results Available

NCT02788474 | COMPLETED | PHASE4

347 participants

Effect of Nintedanib on Biomarkers of Extracellular Matrix Turnover in Patients With Idiopathic Pulmonary Fibrosis and Limited Forced Vital Capacity Impairment

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2016-06-09

Completion:

2017-08-04

Conditions

• Idiopathic Pulmonary Fibrosis

Interventions

• DRUG

Results Available

NCT02741674 | COMPLETED

65093 participants

Comparing the Benefits and Harms of Three Types of Weight Loss Surgery -- The PCORnet® Bariatric Study

Study Type:

OBSERVATIONAL

Last Updated:

2023-12-21

Start Date:

2016-02-29

Completion:

2018-04-30

Conditions

• Obesity
• Bariatrics
• Body Weight
• Diabetes Mellitus
• Weight Loss
• Roux-en-Y Gastric Bypass
• Gastric Bypass

Interventions

• PROCEDURE

No Results Yet

NCT02678572 | COMPLETED | PHASE3

102 participants

Percutaneous Hepatic Perfusion in Patients With Hepatic-dominant Ocular Melanoma

Study Type:

INTERVENTIONAL

Last Updated:

2023-12-21

Start Date:

2016-02-01

Completion:

2023-05-18

Conditions

• Melanoma, Ocular

Interventions

• COMBINATION_PRODUCT

No Results Yet