Clinical Trials Updated in 2022

NCT05243732 | COMPLETED | NA

81 participants

Music Listening for Wellbeing in Adults With Acquired Visual Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2022-01-15
Completion:: 2022-08-30

Conditions

Visual Impairment
Low Vision
Depression
Anxiety
Stress
Emotional Adjustment

Interventions

BEHAVIORAL

No Results Yet

NCT05234203 | COMPLETED | NA

50 participants

The Impact of a Polyphenol-Rich Supplement on Epigenetic and Cellular Markers of Immune Age

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2022-03-25
Completion:: 2022-10-07

Conditions

Immunity Disorders
Aging
Inflammation

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05233696 | WITHDRAWN | PHASE2

0 participants

Radiotherapy in Combo With Chemo and Immunotherapy in Patients With PD-L1 Positive Metastatic TNBC

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2022-01-04
Completion:: 2022-12-01

Conditions

Triple Negative Breast Cancer
Locally Advanced Breast Cancer
Unresectable Breast Carcinoma
Metastatic Breast Cancer
PD-L1 Gene Mutation

Interventions

DRUG
RADIATION

No Results Yet

NCT05213299 | COMPLETED | NA

66 participants

Investigate the Change in Facial Pain Threshold During Auricular Acupuncture in Healthy Volunteers

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2021-12-25
Completion:: 2022-07-01

Conditions

Healthy Volunteers

Interventions

PROCEDURE
OTHER

No Results Yet

NCT05212363 | TERMINATED | NA

12 participants

Lower Leg Compression in Extended Video Game Play: A Pilot Study

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2021-12-09
Completion:: 2022-04-02

Conditions

Compression; Vein
Compression; Artery
Sedentary Behavior
DVT of Legs

Interventions

BEHAVIORAL
DEVICE

No Results Yet

NCT05198778 | COMPLETED | PHASE1

28 participants

A Safety, PK, PD and Food Effect Study of URC102 in Healthy Adults and Patients With Renal Impairment

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2021-11-29
Completion:: 2022-07-13

Conditions

Healthy, Renal Impairment

Interventions

DRUG

No Results Yet

NCT05195684 | COMPLETED | NA

30 participants

MGH Trauma-related Nightmares SDI Study

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2020-06-01
Completion:: 2022-09-30

Conditions

Posttraumatic Stress Disorder

Interventions

OTHER

No Results Yet

NCT05174299 | UNKNOWN | NA

57 participants

The Effect of Multi-target Magnetic Stimulation on Freezing Gait in PD

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2021-10-01
Completion:: 2022-11-30

Conditions

Parkinson Disease

Interventions

DEVICE

No Results Yet

NCT05105854 | ACTIVE_NOT_RECRUITING

120 participants

Hand Osteoarthritis: Investigating Pain Trajectories and Association With Biomarkers Including Estrogen Cohort

Study Type:: OBSERVATIONAL
Last Updated:: 2022-12-06
Start Date:: 2021-07-07
Completion:: 2029-02-07

Conditions

Hand Osteoarthritis

No Results Yet

NCT05077280 | RECRUITING | PHASE2

40 participants

A Study of Concurrent Stereotactic Body Radiotherapy With Opdualag in Metastatic Uveal Melanoma

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2021-09-20
Completion:: 2024-03-31

Conditions

Uveal Melanoma

Interventions

RADIATION
DRUG

No Results Yet

NCT05070585 | UNKNOWN | PHASE1/PHASE2

12 participants

Isothiocyanates and Metabolic Health

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2021-10-20
Completion:: 2022-12-01

Conditions

Metabolic Disturbance

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05062018 | UNKNOWN

534 participants

Vitamin D3 - Omega3 - Home Exercise - HeALTHy Aging and Longevity Cohort

Study Type:: OBSERVATIONAL
Last Updated:: 2022-12-06
Start Date:: 2019-11-26
Completion:: 2023-12-31

Conditions

Healthy Aging

No Results Yet

NCT05061940 | TERMINATED

22 participants

This SCR-103 Protocol Will Permit Sites to Proactively Assess TAA, HLA and HPV-16 Status in Patients With Selected Solid Tumors to Determine Suitability for Repertoire Immune Medicines Treatment Protocols.

Study Type:: OBSERVATIONAL
Last Updated:: 2022-12-06
Start Date:: 2021-05-05
Completion:: 2022-10-11

Conditions

Head and Neck Cancer
Melanoma
HPV-Related Malignancy
HPV-Related Carcinoma
HPV-Related Cervical Carcinoma
HPV Positive Oropharyngeal Squamous Cell Carcinoma
Lung Cancer, Nonsmall Cell
Melanoma (Skin)

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04991376 | COMPLETED

53 participants

Specific miRNAs in Sepsis and Nephrotoxic Antibiotic Treatment

Study Type:: OBSERVATIONAL
Last Updated:: 2022-12-06
Start Date:: 2019-05-02
Completion:: 2021-06-30

Conditions

Sepsis
Septic Shock
Acute Kidney Injury

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04910958 | COMPLETED

411 participants

Impact of COVID-19 Pandemic on Early Spontaneous Abortions and Early Termination of Pregnancy

Study Type:: OBSERVATIONAL
Last Updated:: 2022-12-06
Start Date:: 2021-01-06
Completion:: 2022-08-09

Conditions

Termination of Pregnancy
Covid19
Pregnancy Loss

No Results Yet

NCT04841629 | COMPLETED | NA

42 participants

Perception & Acceptability of a Cervical Cancer Prevention Prebiotic Device

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2022-02-24
Completion:: 2022-11-28

Conditions

Sensory Perceptual Characteristics
User Acceptability of Gel Delivery System

Interventions

OTHER

No Results Yet

NCT04762225 | TERMINATED | PHASE1

7 participants

RPTR-168 in Patients With Human Papillomavirus Strain 16 (HPV-16) E6/E7 Positive Tumors and Melanoma

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2021-05-10
Completion:: 2022-09-14

Conditions

Head and Neck Squamous Cell Carcinoma
Melanoma
Cervical Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT04749238 | COMPLETED | NA

10 participants

Effect of Extracorporeal Adsorption of Plasma Neutrophil Extracellular Traps (NET) in Sepsis

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2021-01-26
Completion:: 2021-10-24

Conditions

Sepsis
Sepsis-associated AKI

Interventions

DEVICE

No Results Yet

NCT04729595 | TERMINATED | PHASE2/PHASE3

248 participants

Study to Evaluate the Effects of Tempol (MBM-02) in COVID-19 Patients.

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2021-09-01
Completion:: 2022-09-21

Conditions

Covid19

Interventions

DRUG
OTHER

No Results Yet

NCT04688242 | UNKNOWN | PHASE2

164 participants

Anal Dilatation Plus Probiotics Before Ileostomy Reduction for Low Anterior Resection Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2021-02-20
Completion:: 2023-12-31

Conditions

Low Anterior Resection Syndrome

Interventions

OTHER
DRUG

No Results Yet

NCT04633902 | UNKNOWN | PHASE2

41 participants

Phase II Study of Olaparib and Pembrolizumab in Advanced Melanoma With Homologous Recombination (HR) Mutation

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2021-03-03
Completion:: 2023-06-30

Conditions

Metastatic Melanoma

Interventions

DRUG

No Results Yet

NCT04601077 | TERMINATED | PHASE1/PHASE2

524 participants

The Evaluation of Nitric Oxide Generating Lozenges on Outcome in Newly Diagnosed COVID-19 Patient of African American and Hispanic Origin

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2020-11-01
Completion:: 2022-11-30

Conditions

COVID-19

Interventions

DRUG

No Results Yet

NCT04566848 | COMPLETED

50 participants

The Status of Immune Checkpoints at Gastrointestinal Cancer

Study Type:: OBSERVATIONAL
Last Updated:: 2022-12-06
Start Date:: 2020-08-01
Completion:: 2022-01-01

Conditions

Gastrointestinal Cancer

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04561388 | WITHDRAWN | NA

0 participants

Electrocochleography Along Cochlear Implant Auditory Rehabilitation

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2022-12-02
Completion:: 2022-12-02

Conditions

Cochlear Prosthesis Implantation

Interventions

PROCEDURE
OTHER

No Results Yet

NCT04540159 | COMPLETED

50 participants

Immune Checkpoints in Intraabdominal Ascites Fluid

Study Type:: OBSERVATIONAL
Last Updated:: 2022-12-06
Start Date:: 2022-01-01
Completion:: 2022-12-01

Conditions

Colorectal Cancer

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04538430 | TERMINATED | NA

7 participants

Peripheral Nerve Stimulation for Back

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2019-11-22
Completion:: 2021-05-15

Conditions

Back Pain

Interventions

DEVICE

Results Available

NCT04510454 | COMPLETED | NA

100 participants

Evaluation of a ddPCR Technology for the SARS-CoV-2 Detection in Symptomatic Patients With Suspicion of COVID-19

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2020-11-02
Completion:: 2021-06-24

Conditions

Cancer
COVID

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04504149 | WITHDRAWN | NA

0 participants

Shared Decision Making for PTSD in Primary Care

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2022-10-03
Completion:: 2022-11-16

Conditions

PTSD

Interventions

BEHAVIORAL

No Results Yet

NCT04467827 | UNKNOWN

200 participants

Connection of Body Posture From the Level and Form of Physical Activity in a Group of Young People

Study Type:: OBSERVATIONAL
Last Updated:: 2022-12-06
Start Date:: 2022-05-16
Completion:: 2023-01-27

Conditions

Body Posture

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT04436666 | COMPLETED | NA

159 participants

Virtual Reality, Ice Application and Self-injection and Self-test Fair, Pain and State Anxiety

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2020-07-15
Completion:: 2020-12-30

Conditions

Injection Site Irritation
Fear of Pain

Interventions

DEVICE
OTHER

No Results Yet

NCT04432428 | COMPLETED | PHASE4

90 participants

Safety and Efficacy of Patient Controlled Analgesia Using the Sublingual Sufentanil Tablet System (SSTS) in a Fast Track Rehabilitation Program After Total Knee Arthroplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2020-05-26
Completion:: 2021-08-31

Conditions

Postoperative Pain

Interventions

DRUG

No Results Yet

NCT04384003 | UNKNOWN | NA

60 participants

Integrated Exercise Therapy Interventions on the Performance and Injury Prevention in Competitive Sports

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2019-08-01
Completion:: 2022-12-31

Conditions

Strain of Fascia of Intrinsic Muscle of Foot (Disorder)
Elastography
Muscle Weakness

Interventions

DEVICE
DIAGNOSTIC_TEST

No Results Yet

NCT04381182 | TERMINATED | NA

20 participants

Heart Rate Variability and Stress Management Enhancement

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2021-09-01
Completion:: 2022-07-20

Conditions

Stress
Heart Rate Variability

Interventions

DEVICE

No Results Yet

NCT04343027 | WITHDRAWN | NA

0 participants

Patient Satisfaction in the Orthopedic Surgery Clinic

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2022-08-31
Completion:: 2022-12-31

Conditions

All

Interventions

BEHAVIORAL

No Results Yet

NCT04310709 | COMPLETED | PHASE2

42 participants

Combination of Regorafenib and Nivolumab in Unresectable Hepatocellular Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2020-06-16
Completion:: 2022-05-30

Conditions

Carcinoma, Hepatocellular
Hepatoma

Interventions

DRUG

No Results Yet

NCT04294680 | COMPLETED | NA

82 participants

Opiate Sparing Versus Opiate Based Following Shoulder Arthroplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2019-08-01
Completion:: 2021-05-31

Conditions

Shoulder Surgery

Interventions

DEVICE

Results Available

NCT04253730 | COMPLETED | NA

10 participants

Characterization of Corticospinal Excitability During Progressive Skin Cooling

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2019-08-22
Completion:: 2022-03-01

Conditions

Hypothermia Due to Cold Environment

Interventions

OTHER

No Results Yet

NCT04172714 | COMPLETED | NA

30 participants

Low-dose Y90 Treatment Planning for HCC

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2019-12-16
Completion:: 2021-06-30

Conditions

HCC
Cancer of Liver
Cancer

Interventions

DEVICE

Results Available

NCT04142983 | COMPLETED | PHASE2/PHASE3

110 participants

Tdap Vaccine Safety for Plasma Donors

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2020-02-03
Completion:: 2021-11-03

Conditions

Tetanus

Interventions

BIOLOGICAL

Results Available

NCT04114370 | COMPLETED | EARLY_PHASE1

9 participants

Evaluation of 18F-fluciclovine (FACBC) PET/MR Uptake in Participants With Glioma

Study Type:: INTERVENTIONAL
Last Updated:: 2022-12-06
Start Date:: 2019-10-22
Completion:: 2021-05-18

Conditions

Glioma

Interventions

DRUG

No Results Yet