Clinical Trials Updated in 2021

NCT05148130 | UNKNOWN

300 participants

Construction and Biological Study of Blood and Placenta Samples Associated With Gestational Diabetes Mellitus

Study Type:: OBSERVATIONAL
Last Updated:: 2021-12-08
Start Date:: 2018-09-11
Completion:: 2022-09-11

Conditions

Gestational Diabetes

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05145218 | UNKNOWN | PHASE3

405 participants

A Clinical Study of TQB2450 Injection Combined With Anlotinib Hydrochloride Capsules Versus Paclitaxel as Weekly Treatment of Relapsed Platinum-resistant Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2021-09-28
Completion:: 2024-10-31

Conditions

Recurrent Platinum-resistant Ovarian Cancer

Interventions

DRUG

No Results Yet

NCT05140850 | UNKNOWN

500 participants

Long-term Consequences of Neuroimaging and Perceived Cognitive Dysfunction in oPRES

Study Type:: OBSERVATIONAL
Last Updated:: 2021-12-08
Start Date:: 2022-01-31
Completion:: 2023-10-31

Conditions

Neuroimaging
Cognitive Dysfunction
Posterior Reversible Encephalopathy Syndrome

Interventions

BIOLOGICAL

No Results Yet

NCT05136040 | COMPLETED | NA

80 participants

Low-Doses Of Isobaric Bupivacaine On Intraoperative Hemodynamics In Spinal Anesthesia During Cesarean Section

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2018-10-15
Completion:: 2019-06-15

Conditions

Cesarean Section
Hemodynamic Instability

Interventions

DRUG

No Results Yet

NCT05134285 | UNKNOWN

1000 participants

Effects of Recurrent PE on Women and Offspring

Study Type:: OBSERVATIONAL
Last Updated:: 2021-12-08
Start Date:: 2022-01-31
Completion:: 2024-11-30

Conditions

Preeclampsia
Recurrence
Hypertension

Interventions

OTHER

No Results Yet

NCT05131802 | COMPLETED

288 participants

Bile Reflux Gastropathy: Prevalence and Risk Factors After Therapeutic Biliary Interventions

Study Type:: OBSERVATIONAL
Last Updated:: 2021-12-08
Start Date:: 2018-01-01
Completion:: 2020-12-15

Conditions

Dyspepsia
Heartburn
Bile Reflux

Interventions

DEVICE

No Results Yet

NCT05130333 | UNKNOWN

120 participants

The Clinical Research of Needle Electrodes Used in Bispectral Index to Monitor the Depth of Anesthesia

Study Type:: OBSERVATIONAL
Last Updated:: 2021-12-08
Start Date:: 2021-11-29
Completion:: 2022-10-22

Conditions

Intraoperative Monitoring
Depth of Anesthesia

Interventions

OTHER

No Results Yet

NCT05121298 | UNKNOWN | PHASE3

155 participants

Discontinuation of Methotrexate in Rheumatoid Arthritis Patients Achieving Clinical Remission by Treatment With Upadacitinib Plus Methotrexate

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2021-01-12
Completion:: 2023-11-30

Conditions

Rheumatoid Arthritis
JAK Inhibitor
Musculoskeletal Ultrasound
Biomarker

Interventions

DRUG

No Results Yet

NCT05120336 | COMPLETED | NA

67 participants

tVNS Effects on Motivation in Depression

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2019-12-11
Completion:: 2021-01-29

Conditions

Major Depressive Disorder

Interventions

DEVICE

No Results Yet

NCT05113719 | COMPLETED | NA

45 participants

Effect of Bridge Exercise Performed at Different Knee Angles

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2020-07-01
Completion:: 2021-07-01

Conditions

Healthy

Interventions

OTHER

No Results Yet

NCT05072561 | UNKNOWN | NA

60 participants

Feasibility of Radioisotope-guided Excision of Mediastinal Lymph Nodes in Patients With Non-small Cells Lung Carcinoma

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2021-05-17
Completion:: 2022-05-01

Conditions

Lung Cancer

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT05034471 | UNKNOWN | NA

12 participants

Mi-STITCH™ and Mi-KNOT™ Device Technologies - Improvement of Mitral Valve Repair

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2021-08-05
Completion:: 2022-03-31

Conditions

Mitral Regurgitation
Mitral Valve Insufficiency

Interventions

DEVICE

No Results Yet

NCT04989322 | UNKNOWN | PHASE2

46 participants

Pembrolizumab, Lenvatinib and Chemotherapy After TKIs in NSCLC

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2021-10-05
Completion:: 2024-08-31

Conditions

Nsclc
EGFR Activating Mutation
EGF-R Positive Non-Small Cell Lung Cancer
ALK Gene Rearrangement Positive
ROS1 Gene Rearrangement
ROS1 Positive NSCLC - Reactive Oxygen Species 1 Positive Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT04901754 | UNKNOWN | PHASE2

38 participants

Camrelizumab Plus Apatinib as Maintenance Therapy in Extensive-stage Small-cell Lung Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2021-07-14
Completion:: 2022-08-15

Conditions

Small Cell Lung Carcinoma

Interventions

DRUG

No Results Yet

NCT04870775 | COMPLETED | NA

108 participants

Effectiveness of a Mindfulness Training Program for Hospital Workers During the Pandemic.

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2021-05-03
Completion:: 2021-10-10

Conditions

Psychopathology

Interventions

BEHAVIORAL

No Results Yet

NCT04867746 | COMPLETED

13 participants

Clinical and Functional Outcomes at Least 2 Years After Hamstring Muscle Repair

Study Type:: OBSERVATIONAL
Last Updated:: 2021-12-08
Start Date:: 2020-12-02
Completion:: 2021-04-15

Conditions

Hamstring Muscle Repair
Hamstring Rupture

Interventions

OTHER

No Results Yet

NCT04704882 | UNKNOWN | NA

162 participants

A Modified Omental Patch Work Decreases Pancreatic Fistula After Lpd

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2021-01-01
Completion:: 2022-05-31

Conditions

Omental Patch
Laparoscopic Pancreaticoduodenectomy
Pancreatic Fistula

Interventions

OTHER

No Results Yet

NCT04682990 | COMPLETED | NA

130 participants

DIAGNOSIS of PULMONARY TUBERCULOSIS Through HUMAN BREATH (TBENOSE)

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2021-01-05
Completion:: 2021-12-05

Conditions

Tuberculosis, Pulmonary
HIV Seropositivity

Interventions

DEVICE
OTHER
DIAGNOSTIC_TEST

No Results Yet

NCT04682288 | COMPLETED | PHASE1

5 participants

Levofloxacin Ocular Implant for Ocular Surgery

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2021-01-04
Completion:: 2021-10-14

Conditions

Cataract

Interventions

DRUG

No Results Yet

NCT04594421 | UNKNOWN

100 participants

Change Trend of Effluent Eosinophil During Peritoneal Dialysis-Related Peritonitis

Study Type:: OBSERVATIONAL
Last Updated:: 2021-12-08
Start Date:: 2021-02-18
Completion:: 2023-12-31

Conditions

Peritonitis

No Results Yet

NCT04580992 | UNKNOWN

25 participants

Defining the Electrocardiographic Effect of Propofol on the Ajmaline Provocation Drug Challenge: A Prospective Trial

Study Type:: OBSERVATIONAL
Last Updated:: 2021-12-08
Start Date:: 2020-11-16
Completion:: 2022-10-31

Conditions

Brugada Syndrome
Channelopathies
Ventricular Fibrillation
Cardiac Death

Interventions

DRUG

No Results Yet

NCT04480216 | COMPLETED | NA

16 participants

MAgnetic Gastrointestinal Universal Septotome: a Safety and Feasibility Study (MAGUS)

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2020-02-19
Completion:: 2021-09-15

Conditions

Diverticulum, Esophageal
Post Gastric Surgery Syndrome

Interventions

DEVICE

No Results Yet

NCT04455178 | UNKNOWN | PHASE4

200 participants

The Comparison Between Spironolactone and Indapamide Monotherapy or in Combination With Amlodipine to Reduce the Risk of Heart Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2020-09-23
Completion:: 2023-12-31

Conditions

Hypertension

Interventions

DRUG

No Results Yet

NCT04339595 | TERMINATED | PHASE4

47 participants

Long-Term Treatment Effect With Tildrakizumab in Participants With Plaque Psoriasis

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2020-01-29
Completion:: 2020-07-31

Conditions

Plaque Psoriasis

Interventions

BIOLOGICAL

No Results Yet

NCT04334577 | COMPLETED | PHASE3

25000 participants

Study on Efficacy of Attenuated Zoster Vaccine, Live

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2020-04-20
Completion:: 2021-07-18

Conditions

Herpes Zoster

Interventions

BIOLOGICAL

No Results Yet

NCT04260776 | WITHDRAWN | PHASE1

0 participants

Adaptive Treatment Strategies for Improving Engagement With a Web-Based Smoking Intervention in Socially Anxious Smokers

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2022-04-15
Completion:: 2024-12-31

Conditions

Social Anxiety Disorder
Tobacco Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT04188769 | WITHDRAWN | NA

0 participants

Effect of Local Pressure on Muscle Activity and General Relaxation in Persons With Hypertonia Following Stroke

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2019-12-31
Completion:: 2020-04-30

Conditions

Deep Pressure
Muscle Activity
General Relaxation
Stroke
Hypertonia, Muscle

Interventions

DEVICE
OTHER

No Results Yet

NCT04166539 | COMPLETED

115 participants

Neurotoxicity and Cardiotoxicity in Total Joint Arthroplasty

Study Type:: OBSERVATIONAL
Last Updated:: 2021-12-08
Start Date:: 2019-10-01
Completion:: 2021-09-27

Conditions

Metallosis
Pain
Total Hip Replacement
Total Knee Replacement

Interventions

BEHAVIORAL
OTHER
RADIATION
DIAGNOSTIC_TEST

No Results Yet

NCT04116879 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated:: 2021-12-08

No Results Yet

NCT04071613 | COMPLETED | PHASE2

104 participants

Tenecteplase Versus Alteplase for Stroke Thrombolysis Evaluation Trial in the Ambulance

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2019-06-20
Completion:: 2021-11-16

Conditions

Stroke, Acute, Stroke Ischemic

Interventions

DRUG

No Results Yet

NCT04063969 | COMPLETED

92 participants

Analysis of the Radiation Safety Climate in the Hybrid Angiography Suite

Study Type:: OBSERVATIONAL
Last Updated:: 2021-12-08
Start Date:: 2019-01-24
Completion:: 2019-08-20

Conditions

Healthy Volunteers
Aortic Aneurysm, Abdominal

Interventions

OTHER

No Results Yet

NCT04026191 | COMPLETED | NA

50 participants

OVT for Epicondylosis (Tennis Elbow)

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2019-07-19
Completion:: 2020-12-31

Conditions

Epicondylitis, Lateral
Tendinopathy, Elbow

Interventions

DEVICE

No Results Yet

NCT04007146 | TERMINATED | NA

1 participants

Systematic Calculation of HyperOxygenation Transit Time

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2020-03-01
Completion:: 2021-09-01

Conditions

Cardiac Output

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT03993574 | UNKNOWN | NA

28 participants

Feasibility of a Stroke Specific Self-management Program

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2019-09-03
Completion:: 2021-12-31

Conditions

Stroke
Chronic Conditions

Interventions

OTHER

No Results Yet

NCT03965377 | UNKNOWN | NA

30 participants

Developing an Injury Prevention Simulation Game to Better Engage Parents in Services -Home Safety Hero

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2019-02-06
Completion:: 2022-08-31

Conditions

Parenting

Interventions

BEHAVIORAL

No Results Yet

NCT03938272 | TERMINATED | PHASE3

22 participants

An Extension Study to Evaluate the Long-term Efficacy and Safety of Oxabact in Patients With Primary Hyperoxaluria

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2019-03-14
Completion:: 2021-07-14

Conditions

Hyperoxaluria, Primary

Interventions

BIOLOGICAL

Results Available

NCT03925142 | COMPLETED | NA

43 participants

Effects of Replacing Starchy Vegetables and Refined Grains With Beef on Cardio-metabolic Disease Risk Factors (S53)

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2019-06-04
Completion:: 2021-10-28

Conditions

Diet Modification

Interventions

OTHER

No Results Yet

NCT03824223 | COMPLETED | NA

20 participants

'Fitness To Fly' Tests In Children With Type II Respiratory Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2019-02-01
Completion:: 2021-08-31

Conditions

Neuromuscular Diseases
Central Hypoventilation

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT03750279 | COMPLETED | NA

50 participants

Inflammatory Targeted Laser Treatment of Knee Osteoarthritis

Study Type:: INTERVENTIONAL
Last Updated:: 2021-12-08
Start Date:: 2018-04-19
Completion:: 2021-08-24

Conditions

Knee Osteoarthritis

Interventions

OTHER

No Results Yet

NCT03673254 | COMPLETED

1026 participants

Evaluation of Practices and Prognostic Factors of Percutaneous Coronary Interventions (PCI) of Calcified Complex Lesions Using Rotational Atherectomy Device.

Study Type:: OBSERVATIONAL
Last Updated:: 2021-12-08
Start Date:: 2016-11-04
Completion:: 2019-01-25

Conditions

Angioplasty

Interventions

DEVICE

No Results Yet