Clinical Trials Updated in 2021

NCT00000762 | COMPLETED | PHASE1

72 participants

A Placebo-Controlled, Phase I Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant Envelope Proteins of HIV-1 gp160 and gp120 in Children >= 1 Month Old With Asymptomatic HIV Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

BIOLOGICAL

No Results Yet

NCT00000761 | COMPLETED | PHASE1

20 participants

Phase I/II Study of Recombinant Human Interferon-gamma (rIFN-gamma) in HIV-Infected Children

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000756 | COMPLETED | PHASE1

15 participants

Evaluation of the Safety and Tolerance of Immunotherapy With Autologous, Ex-Vivo Expanded, HIV-Specific Cytotoxic T-Cells in HIV-Infected Patients With CD4+ Counts Between 100-400/mm3

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000744 | COMPLETED | NA

400 participants

A Randomized, Prospective, Double-Blind Study Comparing Fluconazole With Placebo for Primary and Secondary Prophylaxis of Mucosal Candidiasis in HIV-Infected Women

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

Candidiasis
Candidiasis, Esophageal
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000736 | COMPLETED | PHASE3

3200 participants

Safety and Efficacy of Zidovudine for Asymptomatic HIV-Infected Individuals

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000735 | COMPLETED | PHASE1

12 participants

A Clinical Trial To Evaluate the Toxicity and Antiviral Effects of a Range of Doses of Ampligen in p24 Antigen Positive HIV-Infected Patients With AIDS or ARC

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000733 | COMPLETED | PHASE1

42 participants

Phase I Pharmacokinetic and Tolerance Study of Ribavirin in Human Immunodeficiency Virus (HIV) - Infected Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000732 | COMPLETED | NA

10 participants

Evaluation of the Interaction Between Low Dose Sulfamethoxazole-Trimethoprim and Zidovudine

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000731 | COMPLETED | NA

10 participants

Evaluation of the Interaction Between Acetaminophen and Zidovudine

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000730 | TERMINATED | PHASE3

240 participants

Comparison of Three Treatments for Pneumocystis Pneumonia in AIDS Patients

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

Pneumonia, Pneumocystis Carinii
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000729 | COMPLETED | PHASE1

10 participants

A Multicenter Study To Determine Foscarnet Dose Response in HIV Infected Patients With PGL and/or Constitutional Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000728 | COMPLETED | PHASE1

20 participants

Phase I Trial of the Combination of Zidovudine and Recombinant Interleukin-2 in Patients With Persistent Generalized Lymphadenopathy

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000727 | COMPLETED | PHASE3

322 participants

A Controlled Comparative Trial of Sulfamethoxazole-Trimethoprim Versus Aerosolized Pentamidine for Secondary Prophylaxis of Pneumocystis Carinii Pneumonia in AIDS Patients Receiving Azidothymidine (AZT)

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

Pneumonia, Pneumocystis Carinii
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000726 | COMPLETED | PHASE1

53 participants

Foscarnet Treatment of Serious CMV Retinitis Infection in Patients With Acquired Immunodeficiency Syndrome

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

Cytomegalovirus Retinitis
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000725 | COMPLETED | PHASE1

56 participants

A Phase I Study of AZT and Human Interferon Alpha (Recombinant Alpha-2A and Lymphoblastoid) in the Treatment of AIDS-Associated Kaposi's Sarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

Sarcoma, Kaposi
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000722 | COMPLETED | NA

45 participants

Aerosols in the Treatment of Pneumocystis Pneumonia: A Pilot Study Quantitating the Deposition of Aerosolized Pentamidine as Delivered in ACTG 040 and Comparing Its Toxicity With Parenteral Pentamidine Therapy

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

Pneumonia, Pneumocystis Carinii
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000720 | COMPLETED | PHASE3

250 participants

A Double-Blind, Placebo-Controlled Trial To Evaluate Intravenous Gamma Globulin in Children With Symptomatic HIV Infection Receiving Zidovudine

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000719 | COMPLETED | NA

96 participants

A Trial of Alternating 2',3'-Dideoxycytidine and Zidovudine in the Treatment of Patients With Advanced HIV Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000718 | COMPLETED | NA

112 participants

A Clinical Trial of Alternating and Intermittent Regimens of 2',3'-Dideoxycytidine and 3'-Azido-3'-Deoxythymidine in the Treatment of Patients With AIDS and Advanced ARC

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000715 | COMPLETED | PHASE3

240 participants

A Controlled Trial Comparing the Efficacy of Aerosolized Pentamidine and Parenteral/Oral Sulfamethoxazole-Trimethoprim in the Treatment of Pneumocystis Carinii Pneumonia in AIDS

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

Pneumonia, Pneumocystis Carinii
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000713 | COMPLETED | PHASE1

40 participants

A Phase I Clinical Trial To Evaluate the Toxicity, Antiviral and Immunomodulatory Effects of a Range of Doses of Ampligen in HIV-Infected Subjects

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000706 | COMPLETED | NA

12 participants

Influence of Probenecid and Quinine on the Pharmacokinetics of Azidothymidine

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000704 | COMPLETED | PHASE1

64 participants

A Multicenter Dose Ranging Clinical Trial of 2',3'-Dideoxycytidine in the Treatment of Patients With AIDS and Advanced ARC.

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000703 | COMPLETED | NA

45 participants

Chemotherapy and Azidothymidine, With or Without Radiotherapy, for High Grade Lymphoma in AIDS-Risk Group Members

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

Lymphoma, Non-Hodgkin
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000702 | COMPLETED | PHASE3

315 participants

A Multicenter Placebo-Controlled Double-Blind Trial to Evaluate Azidothymidine (AZT) Treatment of the AIDS Dementia Complex and Central Nervous System (CNS) Human Immunodeficiency Virus (HIV) Infection

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

AIDS Dementia Complex
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000701 | COMPLETED | PHASE1

12 participants

A Phase I Evaluation of Azidothymidine (AZT) in Children With Acquired Immune Deficiency Syndrome (AIDS) or AIDS Related Complex (ARC)

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000691 | COMPLETED | PHASE2

156 participants

A Phase II Dose-Ranging, Open-Labelled Trial of Foscarnet Salvage Therapy for AIDS Patients With Sight-Threatening CMV Retinitis Who Cannot Be Treated With Ganciclovir Due To Myelosuppression or Treatment Failure

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

Cytomegalovirus Retinitis
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000687 | COMPLETED | PHASE2

60 participants

Phase II Study of Zidovudine and Recombinant Alpha-2A Interferon in the Treatment of Patients With AIDS-Associated Kaposi's Sarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

Sarcoma, Kaposi
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000684 | COMPLETED | NA

10 participants

Continuous High-Dose Intravenous Dextran Sulfate in Human Immunodeficiency Virus-Infected Individuals

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000682 | COMPLETED | PHASE3

120 participants

A Randomized, Unblinded Trial of Zidovudine Versus ddC in the Treatment of Patients Status Post PCP Who Received Long-Term Zidovudine Therapy in Protocol ACTG 002

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000681 | COMPLETED | PHASE1

24 participants

A Phase I Study of the Combination of Recombinant GM-CSF, AZT, and Chemotherapy (ABV) (Adriamycin, Bleomycin, Vincristine) in AIDS and Kaposi's Sarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

Sarcoma, Kaposi
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000670 | COMPLETED | NA

16 participants

Safety and Tolerance of Zidovudine With Probenecid and the Effect of Probenecid on Zidovudine Pharmacokinetics Over Four Weeks

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000668 | COMPLETED | PHASE1

48 participants

A Phase I Pharmacokinetic and Tolerance Study of 28-Day Regimens of Oral Ganciclovir

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

Cytomegalovirus Retinitis
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000667 | COMPLETED | PHASE1

20 participants

A Phase I/II Dose Escalation Study of Intradermal gp160 to Evaluate Safety, Delayed Type Hypersensitivity (Skin Test) Responses and Immunogenicity in Asymptomatic HIV Seropositive Patients With More Than 400 CD4+ Cells

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

BIOLOGICAL

No Results Yet

NCT00000660 | COMPLETED | PHASE1

24 participants

Phase I Study of Weekly Oral VP-16 for AIDS-Associated Kaposi's Sarcoma

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

Sarcoma, Kaposi
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000658 | COMPLETED | PHASE3

250 participants

A Phase III Randomized Trial of Low-Dose Versus Standard-Dose mBACOD Chemotherapy With rGM-CSF for Treatment of AIDS-Associated Non-Hodgkin's Lymphoma

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

Lymphoma, Non-Hodgkin
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000657 | COMPLETED | PHASE2

80 participants

Comparison of 2',3'-Dideoxyinosine (Didanosine, ddI) and Zidovudine in Therapy of Patients With the AIDS Dementia Complex

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

AIDS Dementia Complex
HIV Infections

Interventions

DRUG

No Results Yet

NCT00000656 | COMPLETED | PHASE1

116 participants

A Phase I/II, Open Label Study to Evaluate the Antiviral Potential of Combination Zidovudine and 2' 3'-Dideoxyinosine (Didanosine) in Patients With Asymptomatic HIV Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000645 | COMPLETED | PHASE1

32 participants

A Phase I Dose Escalation Study of Synthetic Hypericin in HIV-Infected Patients With Less Than 300 CD4 Lymphocytes

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

HIV Infections

Interventions

DRUG

No Results Yet

NCT00000641 | COMPLETED | PHASE2

90 participants

A Phase II/III Trial of Rifampin, Ciprofloxacin, Clofazimine, Ethambutol, and Amikacin in the Treatment of Disseminated Mycobacterium Avium Infection in HIV-Infected Individuals.

Study Type:: INTERVENTIONAL
Last Updated:: 2021-11-03

Conditions

Mycobacterium Avium-intracellulare Infection
HIV Infections

Interventions

DRUG

No Results Yet