Clinical Trials Updated in 2021

NCT04697446 | UNKNOWN

279 participants

External Control, Observational, Retrospective Study Comparing Pralsetinib to Best Available Therapy in Patients With RET-Fusion Positive NSCLC

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-10
Start Date:: 2020-12-01
Completion:: 2021-10-31

Conditions

RET-fusion Non Small Cell Lung Cancer
Lung Neoplasm
Carcinoma, Non-Small-Cell Lung
Respiratory Tract Neoplasms
Thoracic Neoplasms
Neoplasms by Site
Neoplasms
Lung Diseases
Respiratory Tract Diseases
Carcinoma, Bronchogenic
Bronchial Diseases
Head and Neck Neoplasms
Carcinoma
Neoplasms by Histologic Type
Neoplasms, Germ Cell and Embryonal
Neoplasms, Nerve Tissue
Metastatic Non Small Cell Lung Cancer

No Results Yet

NCT04602585 | UNKNOWN | NA

80 participants

The Effect of Psycho-education on Clinical Outcomes Among Patients With a First Episode Psychosis in Central Uganda

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2021-09-01
Completion:: 2023-07-30

Conditions

Psychosis

Interventions

BEHAVIORAL

No Results Yet

NCT04596839 | COMPLETED | PHASE2

60 participants

Antiviral Activity and Safety of Remdesivir in Bangladeshi Patients With Severe Coronavirus Disease (COVID-19)

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2020-09-04
Completion:: 2021-04-30

Conditions

Covid19

Interventions

DRUG
OTHER

No Results Yet

NCT04579731 | COMPLETED

187 participants

Development of Fecal Scoring for the Management of Fecal Impaction With Regards to Lower Urinary Tract Dysfunction

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-10
Start Date:: 2020-08-25
Completion:: 2021-06-02

Conditions

Fecal Impaction
Lower Urinary Tract Disorder
Bladder Dysfunction
Bowel Dysfunction

Interventions

DRUG

No Results Yet

NCT04574258 | COMPLETED

371 participants

Prospective Multicenter Study on Clinical Application of Sonozoid in Thyroid Tumor

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-10
Start Date:: 2020-10-01
Completion:: 2021-05-01

Conditions

Ultrasound

No Results Yet

NCT04567654 | UNKNOWN

304 participants

Assessment of the Relationship Between Mandibular Third Molars' Roots & the Covering Lingual Cortex Among Egyptian Population Using CBCT

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-10
Start Date:: 2022-01-01
Completion:: 2022-04-01

Conditions

Morphologic Change
Number of Roots

No Results Yet

NCT04551339 | COMPLETED | NA

2700 participants

Zinc Versus Multivitamin Micronutrient Supplementation in the Setting of COVID-19

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2020-09-28
Completion:: 2021-05-28

Conditions

Healthy
Health Care Worker Patient Transmission
Aging

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT04515225 | UNKNOWN

500 participants

COVID-19 Prevalence in HIV-infected Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-10
Start Date:: 2020-11-04
Completion:: 2022-05-03

Conditions

HIV Infections

Interventions

OTHER

No Results Yet

NCT04410510 | UNKNOWN | PHASE2/PHASE3

100 participants

P2Et Extract in the Symptomatic Treatment of Subjects With COVID-19

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2020-09-30
Completion:: 2021-06-30

Conditions

COVID
Coronavirus Infection
SARS-CoV 2
COVID19

Interventions

DRUG
OTHER

No Results Yet

NCT04367337 | COMPLETED

6079 participants

Health Behavior Change During COVID-19 Pandemic

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-10
Start Date:: 2020-03-25
Completion:: 2020-09-24

Conditions

Health Behavior

Interventions

OTHER

No Results Yet

NCT04351100 | COMPLETED

34 participants

Efficacy of Diacerein on Ocular Surface Disease in Degenerative Arthritis Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-10
Start Date:: 2019-10-01
Completion:: 2020-07-31

Conditions

Ocular Surface Disease
Osteoarthritis
Diacerein

Interventions

DRUG

No Results Yet

NCT04334161 | COMPLETED

32 participants

Evaluation of the Neuro-endocrine Response to Post-prandial Hyperinsulinaemic Hypoglycaemia.

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-10
Start Date:: 2020-10-02
Completion:: 2021-07-13

Conditions

Roux-en-y Gastric Bypass
Post Prandial Hypoglycemia

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT04316429 | COMPLETED | NA

35 participants

The Impact of Consumption of Eggs in the Context of Plant-Based Diets on Endothelial Function, Diet Quality, and Cardio-Metabolic Risk Factors in Adults at Risk for Type 2 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2020-06-09
Completion:: 2020-12-22

Conditions

Type 2 Diabetes
Cardiovascular Diseases

Interventions

OTHER

No Results Yet

NCT04306289 | UNKNOWN | NA

20 participants

tDCS and Pain Associated With Diabetic Neuropathy

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2020-06-01
Completion:: 2022-06-06

Conditions

Diabetic Neuropathies
Chronic Pain

Interventions

DEVICE

No Results Yet

NCT04300686 | RECRUITING | PHASE4

40 participants

A Pilot Study in Severe Patients With Takayasu Arteritis.

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2020-03-01
Completion:: 2022-05-01

Conditions

Takayasu Arteritis
Tocilizumab
Adalimumab
Treatment

Interventions

BIOLOGICAL

No Results Yet

NCT04288752 | COMPLETED | NA

176 participants

Efficacy of VR101 as a Personal Lubricant

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2020-02-26
Completion:: 2020-05-01

Conditions

Sexual Dysfunction, Physiological

Interventions

DEVICE

Results Available

NCT04260152 | COMPLETED | NA

30 participants

Evaluation of Geistlich Fibro-Gide® + CAF in Comparison to CTG + CAF for the Treatment of Recession Defects at 6 Months

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2018-09-01
Completion:: 2020-01-04

Conditions

Gingival Recession

Interventions

DEVICE
PROCEDURE

No Results Yet

NCT04208698 | TERMINATED | PHASE2

2 participants

A Scintigraphy Study in Adults With Diabetic Gastroparesis

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2020-02-17
Completion:: 2020-03-31

Conditions

Diabetic Gastroparesis

Interventions

DRUG

Results Available

NCT04201691 | COMPLETED | NA

16 participants

Effect of Manuel Therapy on Tonus, Proprioseption and Balance in Multiple Sclerosis

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2020-01-07
Completion:: 2020-11-02

Conditions

Postural Balance
Multiple Sclerosis
Cervical Region Disorder Nos
Muscle Tonus
Proprioception

Interventions

OTHER

No Results Yet

NCT04187079 | COMPLETED

100 participants

Immunopathologic Profiles and Blood Biomarkers in Patients With IPF

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-10
Start Date:: 2017-09-18
Completion:: 2019-05-01

Conditions

Idiopathic Pulmonary Fibrosis

No Results Yet

NCT04176263 | COMPLETED | NA

52 participants

The Effect of Split-belt Treadmill Training on Gait in Parkinson's Disease

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2019-08-12
Completion:: 2021-05-11

Conditions

Parkinson Disease
Freezing of Gait

Interventions

BEHAVIORAL

No Results Yet

NCT04019600 | SUSPENDED

200 participants

Screening of Pulmonary Hypertension in Methamphetamine Abusers

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-10
Start Date:: 2019-12-23
Completion:: 2022-12-22

Conditions

Methamphetamine Abuse
Pulmonary Hypertension

Interventions

OTHER

No Results Yet

NCT04001686 | UNKNOWN

109 participants

Ambispective Observational Study to Evaluate the Incidence and Management of Aplastic Anemia in Spain

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-10
Start Date:: 2018-01-31
Completion:: 2021-09-01

Conditions

Aplastic Anemia

Interventions

OTHER

No Results Yet

NCT03955796 | WITHDRAWN | NA

0 participants

Performance of a Hydrophilic and a Hydrophobic Intraocular Lens of Similar Design

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2019-05-09
Completion:: 2021-08-03

Conditions

Cataract

Interventions

DEVICE

No Results Yet

NCT03933761 | WITHDRAWN | PHASE2

0 participants

Pamiparib in Fusion Positive, Reversion Negative High Grade Serous Ovarian Cancer or Carcinosarcoma With BRCA1/2 Gene Mutations If Progression on Substrate Poly ADP Ribose Polymerase Inhibitbor (PARPI) or Chemotherapy

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2019-07-29
Completion:: 2021-08-02

Conditions

Ovarian Cancer
Carcinosarcoma

Interventions

DRUG

No Results Yet

NCT03893136 | RECRUITING

1000 participants

The Registry Study of Takayasu Arteritis in East China

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-10
Start Date:: 2016-11-01
Completion:: 2026-05-31

Conditions

Takayasu Arteritis
Mechanisms, Defense
Pregnancy Related
Treatment Refusal
Outcome

Interventions

BIOLOGICAL
DRUG

No Results Yet

NCT03841240 | UNKNOWN

500 participants

The Central Venous Catheter Related Complications in Critically Ill Patients

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-10
Start Date:: 2019-02-19
Completion:: 2021-12-31

Conditions

Catheter Thrombosis
Catheter-Related Infections
Central Venous Catheter Related Bloodstream Infection
Central Venous Catheter Thrombosis

No Results Yet

NCT03814447 | UNKNOWN | EARLY_PHASE1

10 participants

The Fourth Generation CART-cell Therapy for Refractory-Relapsed Ovarian Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2019-08-16
Completion:: 2023-01-31

Conditions

Ovarian Cancer

Interventions

DRUG

No Results Yet

NCT03694613 | COMPLETED | NA

65 participants

Utility of Placental/Umbilical Cord Blood in Early Onset Neonatal Sepsis in Very Low Birth Weight Infants

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2019-06-01
Completion:: 2020-06-01

Conditions

Preterm Infant
Early-Onset Neonatal Sepsis
Umbilical Cord

Interventions

OTHER

Results Available

NCT03605745 | TERMINATED | NA

47 participants

Minimally Invasive Prostatic Vapor Ablation for the Treatment of BPH in Large Prostates (Rezūm XL)

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2018-06-19
Completion:: 2020-06-25

Conditions

BPH With Urinary Obstruction
BPH
BPH With Urinary Obstruction With Other Lower Urinary Tract Symptoms

Interventions

DEVICE

Results Available

NCT03557229 | UNKNOWN | PHASE3

131 participants

Clinical Trial of Antioxidant Therapy in Patients With Septic Shock

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2018-07-23
Completion:: 2022-06-30

Conditions

Oxidative Stress
Septic Shock

Interventions

DRUG

No Results Yet

NCT03534544 | COMPLETED

362 participants

Patient and Parent Preferences for an On-Body Automated Insulin Delivery System

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-10
Start Date:: 2018-08-23
Completion:: 2019-12-17

Conditions

Diabetes Mellitus, Type 1

No Results Yet

NCT03531021 | COMPLETED | NA

45 participants

Increasing Heart Healthy Behaviors in Youth With Type 1 Diabetes

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2018-05-03
Completion:: 2019-02-08

Conditions

Type1diabetes
Cardiovascular Risk Factor

Interventions

BEHAVIORAL

No Results Yet

NCT03450967 | UNKNOWN | PHASE2

31 participants

Durvalumab Plus Tremelimumab Combined With Proton Therapy for HNSCC

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2018-04-11
Completion:: 2021-06-30

Conditions

Head and Neck Squamous Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT03443934 | COMPLETED

89 participants

Hemodynamic Alterations in Liver Cirrhosis Validated by Non-invasive MR Compared to Invasive Assessment

Study Type:: OBSERVATIONAL
Last Updated:: 2021-08-10
Start Date:: 2017-04-01
Completion:: 2021-04-15

Conditions

Portal Hypertension
Liver Diseases
Liver Cirrhoses
Cirrhosis

No Results Yet

NCT03404219 | COMPLETED | NA

31 participants

Motivation and Skills Support (MASS)

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2018-11-01
Completion:: 2020-05-11

Conditions

Schizophrenia
Schizoaffective Disorder

Interventions

BEHAVIORAL

Results Available

NCT03402243 | COMPLETED | NA

47 participants

Effect of Banning Menthol Flavorant on Cigarette and E-Cigarette Use

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2018-02-26
Completion:: 2020-03-25

Conditions

Tobacco Use Disorder

Interventions

OTHER

Results Available

NCT03397030 | COMPLETED | NA

27 participants

Impact of Exercise on Prognostic Biomarkers Related to Prostate Cancer

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2017-01-05
Completion:: 2020-07-09

Conditions

Prostatic Neoplasm

Interventions

OTHER

No Results Yet

NCT03328832 | COMPLETED | PHASE4

70 participants

Combined Topical Tranexamic Acid With Floseal® in Total Knee Arthroplasty

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2017-09-12
Completion:: 2018-09-30

Conditions

Osteoarthritis, Knee

Interventions

DRUG

Results Available

NCT03281486 | COMPLETED | NA

30 participants

"Hyaluronan" Formulation for Type 2 Diabetic Patients With Dry Mouth

Study Type:: INTERVENTIONAL
Last Updated:: 2021-08-10
Start Date:: 2018-01-28
Completion:: 2019-10-31

Conditions

Dry Mouth
Xerostomia
Type 2 Diabetics

Interventions

DEVICE

No Results Yet