Clinical Trials

NCT01027377 | COMPLETED | PHASE1

16 participants

Study of Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc) in Subjects With Severe Hemophilia A

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2009-12-31

Completion:

2010-07-31

Conditions

• Severe Hemophilia A

Interventions

• DRUG

No Results Yet

NCT01027364 | COMPLETED | PHASE3

123 participants

Study of Recombinant Factor IX Fc Fusion Protein (rFIXFc) in Participants With Hemophilia B

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2009-12-31

Completion:

2012-07-31

Conditions

• Severe Hemophilia B

Interventions

• DRUG

Results Available

NCT01007968 | COMPLETED | PHASE1

25 participants

Pharmacokinetics and Safety of Panobinostat in Patients With Advanced Solid Tumors and Various Degrees of Hepatic Function

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2010-03-31

Completion:

2012-11-30

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT00997399 | COMPLETED | PHASE1

37 participants

Study to Evaluate Panobinostat (DACi) Pharmacokinetics and Safety in Solid Tumors and Varying Renal Function

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2010-03-31

Completion:

2014-06-30

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT00987545 | TERMINATED | PHASE2

3 participants

Efficacy 2 Part Study of Identification of Keloid Biomarkers and Effect of QAX576 on Keloid Recurrence

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2009-06-30

Completion:

2010-11-30

Conditions

• Keloids

Interventions

• DRUG

No Results Yet

NCT00986882 | COMPLETED | PHASE2

183 participants

To Evaluate the Safety, Tolerability and Analgesic Efficacy of SAF312 in Postoperative Dental Pain Patients

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2009-09-30

Completion:

2011-03-31

Conditions

• Postoperative Pain

Interventions

• DRUG

No Results Yet

NCT00983060 | COMPLETED | PHASE2

59 participants

Adaptive-design Dose Finding Study to Assess the Antiviral Efficacy and Safety of NIM811 Administered in Combination With Standard of Care (SOC) in Relapsed Hepatitis C Virus 1 (HCV-1) Infected Patients

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2009-09-30

Completion:

2011-04-30

Conditions

• Chronic Hepatitis C Genotype-1 Relapse

Interventions

• DRUG

No Results Yet

NCT00958971 | COMPLETED | PHASE2

43 participants

Safety and Efficacy of TKI258 in FGFR1 Amplified and Non-amplified Metastatic HER2 Negative Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2009-07-31

Completion:

2011-03-31

Conditions

• Metastatic Breast Cancer

Interventions

• DRUG

No Results Yet

NCT00929968 | COMPLETED | PHASE2

35 participants

Safety, Tolerability and Pharmacokinetics of Multiple Doses of VAK694 in Atopic Subjects With Seasonal Rhinitis

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2009-06-30

Completion:

2011-02-28

Conditions

• Allergic Rhinitis

Interventions

• BIOLOGICAL
• DRUG

No Results Yet

NCT00913653 | COMPLETED | PHASE2

30 participants

Safety/Tolerability, Pharmacokinetics/Pharmacodynamics (PK/PD) of LCZ696 in Patients With Stable Heart Failure

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2009-05-31

Completion:

2009-07-31

Conditions

• Heart Failure

Interventions

• DRUG

No Results Yet

NCT00907894 | COMPLETED | PHASE1

22 participants

Pharmacokinetics and Safety of Single-Dose Telbivudine in Children and Adolescents With Chronic Hepatitis B

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2009-02-28

Completion:

2012-03-31

Conditions

• Chronic Hepatitis B

Interventions

• DRUG

No Results Yet

NCT00880308 | COMPLETED | PHASE1

103 participants

Dose Finding and Safety of Oral LDE225 in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2009-03-31

Completion:

2013-07-31

Conditions

• Advanced Solid Tumor Cancers
• Medulloblastoma
• Basal Cell Carcinoma

Interventions

• DRUG

No Results Yet

NCT00846989 | COMPLETED | PHASE1/PHASE2

276 participants

Efficacy, Tolerability and Safety of RKI983 (0.05% & 0.10%) vs Xalatan in Patients With POAG or Ocular Hypertension

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2009-01-31

Completion:

2009-04-30

Conditions

• Glaucoma
• Ocular Hypertension

Interventions

• DRUG

No Results Yet

NCT00790426 | COMPLETED | PHASE2

44 participants

Phase II Study of TKI258 in Advanced Urothelial Carcinoma

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2010-03-31

Completion:

2012-04-30

Conditions

• Urothelial Cancer

Interventions

• DRUG

No Results Yet

NCT00788931 | COMPLETED | PHASE1

15 participants

A Trial l of Panobinostat Given in Combination With Trastuzumab and Paclitaxel in Adult Female Patients With HER2 Positive Metastatic Breast Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2008-12-31

Completion:

2010-08-31

Conditions

• HER-2 Positive Breast Cancer
• Metastatic Breast Cancer

Interventions

• DRUG

No Results Yet

NCT00757757 | TERMINATED | PHASE1/PHASE2

3 participants

A Phase I/II Open-label Study of MCS110 in Patients With Prostate Cancer and Bone Metastases

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2008-09-30

Completion:

2009-08-31

Conditions

• Prostate Cancer
• Bone Metastases

Interventions

• DRUG

No Results Yet

NCT00750295 | COMPLETED | PHASE1/PHASE2

60 participants

A Clinical Study to Evaluate the Safety, Tolerability and Activity of a New Phosphate Binder (SBR759) in Patients With Chronic Kidney Disease on Hemodialysis

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2007-02-28

Completion:

2008-01-31

Conditions

• Chronic Kidney Disease

Interventions

• DRUG

No Results Yet

NCT00739414 | COMPLETED | PHASE1

14 participants

Dose-escalating Study of LBH589 in Adult Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2008-07-31

Completion:

2009-11-30

Conditions

• Cancer
• Advanced Solid Tumor

Interventions

• DRUG

No Results Yet

NCT00728351 | COMPLETED | PHASE3

317 participants

Efficacy and Safety of Fixed Combination Therapy of Vildagliptin and Metformin (25/1000 mg Bid) in Patients With Type 2 Diabetes Inadequately Controlled With Prior Metformin Monotherapy (HbA1c 7.0-9.5%)

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2008-06-30

Completion:

2010-02-28

Conditions

• Diabetes Mellitus, Type 2

Interventions

• DRUG

No Results Yet

NCT00716716 | COMPLETED | PHASE1

10 participants

Phase I/IIa Study of FIXFc in Hemophilia B Patients

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2008-04-30

Completion:

2009-10-31

Conditions

• Hemophilia B

Interventions

• DRUG

No Results Yet

NCT00704483 | COMPLETED | PHASE2

321 participants

Efficacy of SBR759 in Lowering Serum Phosphate Levels in Chronic Kidney Disease Patients on Hemodialysis

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2008-07-31

Completion:

2010-08-31

Conditions

• Hyperphosphatemia Patients With Chronic Kidney Disease on 3x/Week Replacement Therapy

Interventions

• DRUG

No Results Yet

NCT00663832 | COMPLETED | PHASE1

44 participants

A Dose Finding Study With I.V. Panobinostat (LBH589), Docetaxel, and Prednisone in Patients With Hormone Refractory Prostate Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2008-02-29

Completion:

2011-12-31

Conditions

• Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT00624702 | COMPLETED | PHASE1

98 participants

Tolerability of Indacaterol Salts (Maleate, Xinafoate and Acetate) in Comparison to Placebo in Patients With Mild to Moderate Persistent Asthma

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2008-02-29

Completion:

2008-09-30

Conditions

• Asthma

Interventions

• DRUG

No Results Yet

NCT00581997 | TERMINATED | PHASE2

8 participants

QAX576 in Patients With Pulmonary Fibrosis Secondary to Systemic Sclerosis

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2007-12-31

Completion:

2009-04-30

Conditions

• Pulmonary Fibrosis Secondary to Systemic Sclerosis

Interventions

• DRUG

No Results Yet

NCT00570284 | COMPLETED | PHASE1

36 participants

A Study to Investigate the Effect of Food on Oral LBH589 Absorption in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2007-11-30

Completion:

2011-02-28

Conditions

• Cancer

Interventions

• DRUG

No Results Yet

NCT00535951 | COMPLETED | PHASE1

18 participants

Pharmacokinetic, Safety, and Efficacy Effects of Oral LBH589 on Dextromethorphan in Patients With Advanced or Metastatic Non-Small Cell Lung Cancer or Malignant Pleural Mesothelioma

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2007-11-30

Completion:

2009-01-31

Conditions

• Carcinoma, Non-Small-Cell Lung
• Mesothelioma

Interventions

• DRUG

No Results Yet

NCT00532675 | COMPLETED | PHASE1

46 participants

Safety Study of LBH589 When Given in Combination With Lenalidomide and Dexamethasone in Adult Patients With Multiple Myeloma.

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2008-04-22

Completion:

2017-11-08

Conditions

• Multiple Myeloma

Interventions

• DRUG
• COMBINATION_PRODUCT

No Results Yet

NCT00532389 | COMPLETED | PHASE1

62 participants

Safety Study of LBH589 When Given in Combination With Bortezomib in Adult Patients With Multiple Myeloma

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2007-10-31

Completion:

2013-10-31

Conditions

• Multiple Myeloma

Interventions

• DRUG

No Results Yet

NCT00532350 | COMPLETED | PHASE1

22 participants

Safety and Tolerability QAT370 Compared to Tiotropium in Patients With Chronic Obstructive Pulmonary Disease

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2007-07-31

Conditions

• Chronic Obstructive Pulmonary Disease

Interventions

• DRUG

No Results Yet

NCT00532233 | COMPLETED | PHASE2

52 participants

SD, IL-13 Production Rate in IPF

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2007-09-30

Completion:

2009-06-30

Conditions

• Idiopathic Pulmonary Fibrosis

Interventions

• DRUG

No Results Yet

NCT00506792 | COMPLETED | PHASE2

9 participants

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QAU145 in Patients With Cystic Fibrosis

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2007-07-31

Completion:

2008-12-31

Conditions

• Cystic Fibrosis

Interventions

• DRUG

No Results Yet

NCT00503451 | COMPLETED | PHASE1

14 participants

A Study to Investigate the Effects of Ketoconazole on LBH589 in Patients With Advanced Solid Tumors

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2007-09-30

Completion:

2010-04-30

Conditions

• Non-Hodgkin Lymphoma
• Neoplasms

Interventions

• DRUG

No Results Yet

NCT00493766 | TERMINATED | PHASE1

16 participants

Safety of LBH589 Alone and in Combination With IV Docetaxel and Prednisone

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2006-05-31

Completion:

2008-07-31

Conditions

• Hormone Refractory Prostate Cancer

Interventions

• DRUG

No Results Yet

NCT00468039 | COMPLETED | PHASE3

94 participants

A Sub-study to LMF237A2302 to Assess the Effect of 24 Weeks Treatment With Initial Combination of Vildagliptin Plus Metformin

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2007-03-06

Completion:

2008-06-06

Conditions

• Diabetes Mellitus, Type 2

Interventions

• DRUG

No Results Yet

NCT00441610 | COMPLETED | PHASE1

4 participants

An Extension Trial to a Phase I Dose Escalation Study of Gimatecan Administered Orally 5 Consecutive Days to Japanese Patients With Advanced Solid Tumor

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2007-01-31

Completion:

2009-09-30

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT00420381 | COMPLETED | PHASE2

28 participants

Evaluation of Enzastaurin in the Treatment of Persistent or Recurrent Ovarian or Primary Peritoneal Cancer

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2007-01-31

Completion:

2008-05-31

Conditions

• Ovarian Cancer
• Neoplasms
• Carcinoma

Interventions

• DRUG

Results Available

NCT00410358 | COMPLETED | PHASE1

19 participants

A Dose Escalation of Gimatecan Administered Orally to Japanese Patients With Advanced Solid Tumor.

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2006-06-30

Completion:

2008-02-29

Conditions

• Advanced Solid Tumors

Interventions

• DRUG

No Results Yet

NCT00399841 | TERMINATED | NA

13 participants

Spinal Cord Stimulation (SCS) for Neuropathic Pain of Back or Lower Extremity

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2006-11-30

Completion:

2008-05-31

Conditions

• Intractable Neuropathic Pain
• Pain
• Back Pain
• Lower Extremity Pain

Interventions

• DEVICE

Results Available

NCT00397241 | COMPLETED | PHASE4

33 participants

24-hour Study of Dorzolamide/Timolol and Latanoprost/Timolol Fixed Combinations

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2006-09-30

Completion:

2007-12-31

Conditions

• Open-angle Glaucoma

Interventions

• DRUG

No Results Yet

NCT00382096 | COMPLETED | PHASE3

1179 participants

Efficacy of Fixed Combination Therapy of Vildagliptin and Metformin Compared to the Individual Monotherapy Components in Drug Naive Patients With Type 2 Diabetes

Study Type:

INTERVENTIONAL

Last Updated:

2020-12-19

Start Date:

2006-09-30

Completion:

2008-06-03

Conditions

• Diabetes Mellitus, Type 2

Interventions

• DRUG

No Results Yet