Phase II Study of TKI258 in Advanced Urothelial Carcinoma
NCT00790426 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 44
Last updated 2020-12-19
Summary
This study will evaluate the efficacy of TKI258 in patients with advanced urothelial cancer
Conditions
Interventions
- DRUG
-
TKI258
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Novartis Pharmaceuticals · Novartis Pharmaceuticals
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-03-31
- Primary Completion
- 2012-04-30
- Completion
- 2012-04-30
Countries
- United States
- Austria
- Canada
- Germany
- Italy
- Spain
- Taiwan
- United Kingdom
Study Locations
More Related Trials
-
Trastuzumab and Combination Chemotherapy in Treating Patients With Locally Recurrent or Metastatic Urinary Tract Cancer
NCT00005831 ·Status: COMPLETED ·Phase: PHASE2
-
Atezolizumab Immunotherapy, in Immunotherapy Naive Patients With Urinary Tract Squamous Cell Carcinoma (UTSCC).
NCT05038657 ·Status: UNKNOWN ·Phase: PHASE2
-
A Phase 3 Single-Arm Study of UGN-102 for Treatment of Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder Cancer
NCT05243550 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Trilaciclib, a CDK 4/6 Inhibitor, in Patients With Advanced/Metastatic Bladder Cancer Receiving Chemotherapy Then Avelumab
NCT04887831 ·Status: TERMINATED ·Phase: PHASE2
-
A Single-Arm Study of Bempegaldesleukin (NKTR-214) Plus Nivolumab in Cisplatin Ineligible Patients Who Have Locally Advanced or Metastatic Urothelial Cancer
NCT03785925 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations
NCT05544552 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
A Study to Evaluate TAR-210 Versus Intravesical Chemotherapy Treatment in Participants With High Risk Non-Muscle-Invasive Bladder Cancer
NCT06919965 ·Status: RECRUITING ·Phase: PHASE3
-
Intervention of Bladder Cancer by CAR-T
NCT03185468 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC
NCT06567743 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of Oral Erdafitinib in People With Recurrent Non-Invasive Bladder Cancer
NCT04917809 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
KHK2455 (IDO Inhibitor) Plus Avelumab in Adult Subjects With Advanced Bladder Cancer
NCT03915405 ·Status: TERMINATED ·Phase: PHASE1
-
Erlotinib Hydrochloride in Treating Patients With Bladder Cancer Undergoing Surgery
NCT02169284 ·Status: TERMINATED ·Phase: PHASE2
-
Trastuzumab in Treating Patients With Previously Treated, Locally Advanced, or Metastatic Cancer of the Urothelium
NCT00004856 ·Status: TERMINATED ·Phase: PHASE2
-
A Study of TAR-200 Versus Intravesical Chemotherapy in Participants With Recurrent High-Risk Non-Muscle-Invasive Bladder Cancer (HR-NMIBC) After Bacillus Calmette-Guérin (BCG)
NCT06211764 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Phase 2b Study of UGN-102 for Low Grade Intermediate Risk Non-Muscle-Invasive Bladder Cancer
NCT03558503 ·Status: COMPLETED ·Phase: PHASE2
-
Pre-Approval Expanded Access Study for TAR-200 Treating Physician Use
NCT06877676 ·Status: APPROVED_FOR_MARKETING
-
Study of Tipifarnib in Patients With Previously-Treated, Advanced, HRAS Mutant Urothelial Carcinoma
NCT02535650 ·Status: UNKNOWN ·Phase: PHASE2
-
Study on the Occurrence of Possible Relapses and on the Quality of Life in Patients Who Underwent TURBK.
NCT06167356 ·Status: RECRUITING
-
Atezolizumab in Treating Patients With Recurrent BCG-Unresponsive Non-muscle Invasive Bladder Cancer
NCT02844816 ·Status: COMPLETED ·Phase: PHASE2
-
BGJ398 in Non-Muscle-Invasive Urothelial Carcinoma of the Bladder
NCT02657486 ·Status: COMPLETED ·Phase: NA
-
A Study of Erdafitinib Intravesical Delivery System in Japanese Participants With Bladder Cancer
NCT05567185 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Study of TAR-200 in Participants With Muscle-Invasive Urothelial Carcinoma of the Bladder Who Are Ineligible for or Refuse Cisplatin-based Chemotherapy and Who Are Unfit for Radical Cystectomy
NCT03404791 ·Status: COMPLETED ·Phase: PHASE1
-
Bortezomib in Treating Patients With Advanced or Metastatic Transitional Cell Cancer of the Bladder, Renal Pelvis, or Ureter
NCT00066352 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer
NCT06319820 ·Status: RECRUITING ·Phase: PHASE3
-
Genomic Based Assignment of Therapy in Advanced Urothelial Carcinoma
NCT02788201 ·Status: COMPLETED ·Phase: PHASE2