MedTrace Logo

Short Sprint Interval Training in People With Multiple Sclerosis

NCT07804264 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2026-09-04

No results posted yet for this study

Summary

The goal of this clinical trial is to learn whether a short sprint interval training protocol on a cycle ergometer can improve physical function, walking, muscle strength, exercise capacity, fatigue, cognitive processing speed, and patient-reported outcomes in people with multiple sclerosis.

The main questions it aims to answer are:

1. Does short sprint interval training improve walking performance, lower-limb coordination, muscle strength, exercise capacity, fatigue, and cognitive processing speed in people with multiple sclerosis?
2. How do participants respond to short sprint interval training in terms of heart rate, power, cadence, perceived exertion, and affective valence?
3. What adverse events or unintended effects, if any, occur during the intervention?

Researchers will compare short sprint interval training with usual physical activity to see if this exercise program improves physical, cognitive, and patient-reported outcomes.

Participants will:

1. Be randomly assigned to either a short sprint interval training group or a usual physical activity group.
2. Complete assessments before and after the 2-week training period.
3. Continue their usual physical activity if they are assigned to the control group.
4. Complete 6 supervised exercise sessions over 2 weeks if they are assigned to the short sprint interval training group.
5. During each exercise session, perform short 5-second high-intensity cycling sprints on a recumbent cycle ergometer, separated by recovery periods.
6. Complete walking, strength, stepping, calf endurance, fatigue, and cognitive processing speed assessments.

Conditions

Interventions

OTHER

Short sprint interval training

Participants will perform a supervised short sprint interval training program on a recumbent cycle ergometer for 2 weeks, with 3 sessions per week. Each session will include a 5-minute warm-up at an easy intensity, followed by repeated 5-second high-intensity cycling sprints separated by 40 seconds of active recovery. The number of sprints will increase progressively across sessions from 5 to 9, with a reduced number of sprints in the final session.

Sponsors & Collaborators

  • Hasselt University

    collaborator OTHER

  • University of Leon

    collaborator UNKNOWN

  • El Bierzo Hospital

    collaborator UNKNOWN

  • Sil Multiple Sclerosis Association

    collaborator UNKNOWN

  • Universidad de León

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-09-30
Primary Completion
2026-10-31
Completion
2026-10-31

Countries

  • Spain

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07804264 on ClinicalTrials.gov