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Effects of Interrupting Prolonged Sitting With Different Standing Intervals on Vascular Health in Women

NCT07802574 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2026-09-03

No results posted yet for this study

Summary

The goal of this clinical trial is to examine the effects of interrupting prolonged sitting with different standing intervals on vascular health in healthy women aged 18-45 years. The main questions it aims to answer are:

Does interrupting prolonged sitting with short standing intervals (10 minutes every hour) improve blood pressure and pulse wave velocity more than prolonged continuous standing intervals (30 minutes every hour)? Does interrupting prolonged sitting with prolonged intermittent standing intervals (30 minutes every hour divided into three 10-minute standing bouts) improve blood pressure and pulse wave velocity more than prolonged continuous standing intervals (30 minutes every hour)?

The researcher will compare three different sitting interruption conditions to evaluate their effects on vascular health outcomes:

Standing for 10 minutes every hour. Continuous standing for 30 minutes every hour. Intermittent standing for 30 minutes every hour divided into three 10-minute standing bouts.

Participants will:

Attend three experimental sessions in random order separated by at least 7 days.

Complete 3 hours of sitting with different standing interruption protocols. Undergo measurements of blood pressure, pulse wave velocity, and heart rate before sitting and after each hour of the experiment.

Undergo height, weight, and body mass index measurements.

Conditions

  • Prolonged Sitting
  • Vascular Health
  • Sedentary Behavior

Interventions

BEHAVIORAL

Short Standing Interval

Participants will interrupt prolonged sitting with 10 minutes of standing every hour during 3 hours of sitting.

BEHAVIORAL

Continuous Standing Interval

Participants will interrupt prolonged sitting with 30 continuous minutes of standing every hour during 3 hours of sitting.

BEHAVIORAL

Intermittent Standing Interval

Participants will interrupt prolonged sitting with 30 minutes of standing every hour divided into three 10-minute standing bouts during 3 hours of sitting.

Sponsors & Collaborators

  • King Saud University

    lead OTHER

Principal Investigators

  • Abdullah B Alansare, PhD · King Saud University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-04-02
Primary Completion
2026-09-20
Completion
2026-10-10

Countries

  • Saudi Arabia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07802574 on ClinicalTrials.gov