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Muscle Oxygenation in Patients With COPD Exacerbation

NCT07801547 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2026-09-03

No results posted yet for this study

Summary

Chronic obstructive pulmonary disease (COPD) is often complicated by acute exacerbations, which lead to functional impairments, increased dyspnea, and a rapid decline in lung function. During an exacerbation, impaired pulmonary gas exchange, systemic inflammation, and increased work of breathing significantly alter oxygen availability and metabolic demand in skeletal muscles. The aim of this study is to evaluate and compare respiratory and peripheral muscle oxygenation in patients with acute exacerbation of COPD (AECOPD) and patients with clinically stable COPD. By examining these physiological changes, the study seeks to determine the impact of exacerbations on muscle function and oxygenation efficiency

Conditions

  • COPD (Chronic Obstructive Pulmonary Disease)
  • Acute Exacerbation Chronic Obstructive Pulmonary Disease
  • Muscle Oxygenation

Sponsors & Collaborators

  • Hacettepe University

    lead OTHER

Principal Investigators

  • Aynur Demirel · Hacettepe University

Eligibility

Min Age
40 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-08-30
Primary Completion
2027-10-05
Completion
2028-02-05

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07801547 on ClinicalTrials.gov