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Anodic Stimulation in Parkinson's Disease

NCT07798999 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2026-09-02

No results posted yet for this study

Summary

Randomized, double-blind, crossover design, interventional study to assess the differences between mixed cathodic/anodic, pure cathodic, and pure anodic stimulation with respect to efficacy, side effect thresholds, symptom control, and quality of life in Parkinson's Disease patients implanted with Boston Scientific Cartesia directional DBS leads in the bilateral STN.

Conditions

  • Parkinson Disease (PD)

Interventions

DEVICE

Mixed Cathodic/Anodic

Mixed cathodic/anodic stimulation setting on the Boston Scientific Vercise DBS system.

DEVICE

Pure Cathodic

Pure cathodic stimulation setting on the Boston Scientific Vercise DBS system.

DEVICE

Pure Anodic

Pure anodic stimulation setting on the Boston Scientific Vercise DBS system.

Sponsors & Collaborators

  • Boston Scientific Corporation

    collaborator INDUSTRY

  • University of South Florida

    lead OTHER

Principal Investigators

  • Yarema Bezchlibnyk · University of South Florida

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
40 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-02-17
Primary Completion
2027-02-28
Completion
2027-02-28
FDA Device
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07798999 on ClinicalTrials.gov