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Intravenous Magnesium Sulphate Versus Lignocaine for Attenuating Hemodynamic Responses to Laryngoscopy and Endotracheal Intubation

NCT07793955 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 78

Last updated 2026-08-31

No results posted yet for this study

Summary

This study will compare intravenous magnesium sulfate with intravenous lidocaine for reducing the cardiovascular response to endotracheal intubation in adult patients undergoing general anesthesia. Eligible participants will receive either magnesium sulfate or lidocaine before endotracheal intubation. Heart rate and blood pressure will be recorded at predefined time points before and after intubation to compare the effectiveness of the two interventions in attenuating the hemodynamic response to laryngoscopy and endotracheal intubation.

Conditions

  • Hemodynamic Response to Laryngoscopy and Orotracheal Intubation

Interventions

DRUG

Magnesium Sulphate infusion

intravenous magnesium Sulphate 30mg /kg diluted in 100ml normal saline, administered 90 sec before induction of general anesthesia

Sponsors & Collaborators

  • Lady Reading Hospital, Pakistan

    lead OTHER_GOV

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-08-20
Primary Completion
2026-09-20
Completion
2026-09-20

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07793955 on ClinicalTrials.gov