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Photon-counting CT Scan vs Standard HRCT Scan in the Identification of Idiopathic Pulmonary Fibrosis

NCT07790614 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 156

Last updated 2026-08-27

No results posted yet for this study

Summary

The CT-IPF ANTHEM study is designed to prospectively compare PCDCT to HRCT scan in the identification of specific ILD diagnosis discussed during the multidisciplinary discussion to increase diagnostic confidence and reduce unclassifiable ILD cases.

Conditions

  • IPF
  • ILD
  • Interstitial Lung Disease (ILD)
  • Interstitial Lung Diseases
  • Idiopathic Pulmonary Fibrosis
  • Idiopathic Pulmonary Fibrosis (IPF)
  • CT Photon-Counting
  • CT Scan
  • CT
  • Interstitial Lung Disease Due to Systemic Disease (Telomere Biology Disorder)

Interventions

DIAGNOSTIC_TEST

Photon counting CT

Non-contrast enhanced CT will be acquired in spectral ultra-high-resolution mode on a clinical dual-source photon-counting detector CT (PCDCT) (NAEOTOM Alpha, Siemens Healthineers AG, Forchheim, Germany). All scans will be acquired with automated exposure control.

Sponsors & Collaborators

  • Istituto Clinico Humanitas

    lead OTHER

Principal Investigators

  • Francesco Amati, MD · Humanitas Research Hospital IRCCS, Rozzano-Milan

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-03-25
Primary Completion
2026-12-31
Completion
2026-12-31

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07790614 on ClinicalTrials.gov