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EMS vs. Resistance Training in Overweight Women

NCT07787286 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 42

Last updated 2026-08-26

No results posted yet for this study

Summary

This study aims to compare the effects of eight weeks of resistance training versus electrical muscle stimulation (EMS) on oxidative stress indicators and cellular health index in overweight and obese women aged 35-45 years. Forty-two participants will be randomly assigned to three groups: resistance training, EMS, and control. The resistance training group will perform progressive resistance exercises three times per week for eight weeks. The EMS group will receive electrical muscle stimulation on biceps, abdominal, back, and quadriceps muscles three times per week for eight weeks. The control group will receive no intervention. Oxidative stress markers including superoxide dismutase (SOD), glutathione peroxidase (GPX), catalase (CAT), glutathione, protein carbonyl (PC), and total antioxidant capacity (TAC) will be measured from blood samples. Cellular health will be assessed using phase angle (PhA) derived from bioelectrical impedance analysis. Upper and lower body muscular strength and endurance will also be evaluated. All measurements will be taken at baseline and 48 hours after the last training session. The primary outcome is change in phase angle. Secondary outcomes include changes in oxidative stress markers and physical performance.

Conditions

  • Obesity & Overweight

Interventions

OTHER

Resistance Training

Progressive resistance training program including upper body (chest press), back (lat pulldown), abdominal (crunch), and lower body (squat) exercises. Performed 3 times per week for 8 weeks. Each session includes warm-up (10 min), main exercises (30 min), and cool-down (10 min). Intensity: 60-85% of 1RM, progressing weekly.

DEVICE

Electrical Muscle Stimulation

Electrical muscle stimulation applied to biceps brachii, abdominals, back, and quadriceps muscles using a commercial EMS device. Parameters: frequency 35-70 Hz, pulse duration 100 μs, pulse period 50 ms, electrode size 150 × 240 mm. Performed 3 times per week for 8 weeks, 15 minutes per session. Intensity progressively increased based on participant tolerance.

OTHER

No Intervention

Participants in the control group receive no exercise intervention during the 8-week study period.

Sponsors & Collaborators

  • Birjand University of Medical Sciences

    lead OTHER

Principal Investigators

  • Mohsen Mohammadnia Ahmadi, PhD · university of birjand

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
35 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-09-15
Primary Completion
2026-11-15
Completion
2026-11-25

Countries

  • Iran

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07787286 on ClinicalTrials.gov