Identifying Biomarkers of Response to Digital Interventions for Mood Disorders

Summary

The proposed study will be a single-arm pragmatic clinical trial examining the feasibility of online CBT within the CAN-BIND sites and the biomarkers of treatment response to online CBT for mood disorders.

Conditions

• Depression / Major Depressive Disorder
• Bipolar Disorder (BD)

Interventions

BEHAVIORAL

Online Cognitive Behavioural Therapy

The Wellbeing course is an online program that educates and guides users in cognitive behavioural therapy techniques with downloadable guides, client stories and interactive exercises to help manage symptoms of mood concerns.

Sponsors & Collaborators

• Ontario Brain Institute

  collaborator OTHER

• McMaster University

  collaborator OTHER

• Queen's University

  collaborator OTHER

• University of Ottawa

  collaborator OTHER

• University of British Columbia

  collaborator OTHER

• University of Calgary

  collaborator OTHER

• Dalhousie University

  collaborator OTHER

• University of Michigan

  collaborator OTHER

• Simon Fraser University

  collaborator OTHER

• Ontario Shores Centre for Mental Health Sciences

  collaborator OTHER

• University of Regina

  collaborator OTHER

• University of Texas Southwestern Medical Center

  collaborator OTHER

• University Health Network, Toronto

  collaborator OTHER

• St. Joseph's Healthcare Hamilton

  collaborator OTHER

• Nova Scotia Health Authority

  collaborator OTHER

• The Canadian Biomarker Integration Network in Depression

  collaborator UNKNOWN

• Centre for Addiction and Mental Health

  lead OTHER

Principal Investigators

• Lena C. Lena, PhD · Centre for Addiction and Mental Health

Study Design

Allocation

NA

Purpose

TREATMENT

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

16 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2026-07-28

Primary Completion

2029-07-28

Completion

2029-07-28

Countries

• Canada

Study Locations