Comparison of Two Drugs Bupivacaine and Ropivacaine for Postoperative Analgesia in Bilateral Superficial Cervical Plexus Block After Thyroidectomy
NCT07779551 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 94
Last updated 2026-08-21
Summary
There is significant difference between bupivacaine and ropivacaine in terms of postoperative pain assessment in patients undergoing total thyroidectomy with bilateral superficial cervical plexus block.
Conditions
- Postoperative Pain
Interventions
- PROCEDURE
-
Group 1 will receive 10ml of 0.25% bupivacaine
After placing the patients in a supine position with the neck slightly extended and rotated away from the side to be blocked,the procedure will be performed under sterile aseptic conditions.The sternocleidomastoid muscle will be identified,and a high-frequency (1O MHz) linear probe will be positioned transversely over the muscle,between the mastoid and clavicle. The cutaneous nerves of the cervical plexus,visible as round hypoechoic structures in the fascial plane beneath the muscle,will be targeted using a 22-gauge short block needle (5 cm) inserted in-plane with the transducer. Negative aspiration will be performed during injection to avoid inadvertent intravascular delivery. An emergency crash cart will remain available throughout the procedure.
- PROCEDURE
-
Group 2 will receive 10ml of 0.25% ropivacaine on each side.
After placing the patients in a supine position with the neck slightly extended and rotated away from the side to be blocked,the procedure will be performed under sterile aseptic conditions.The sternocleidomastoid muscle will be identified,and a high-frequency (1O MHz) linear probe will be positioned transversely over the muscle,between the mastoid and clavicle. The cutaneous nerves of the cervical plexus,visible as round hypoechoic structures in the fascial plane beneath the muscle,will be targeted using a 22-gauge short block needle (5 cm) inserted in-plane with the transducer. Negative aspiration will be performed during injection to avoid inadvertent intravascular delivery. An emergency crash cart will remain available throughout the procedure
Sponsors & Collaborators
-
Sargodha Medical College
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 20 Years
- Max Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2026-01-22
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
Countries
- Pakistan
Study Locations
More Related Trials
-
Superficial Cervical Plexus Block and Quality of Recovery After Thyroidectomy
NCT06002152 ·Status: COMPLETED ·Phase: PHASE2
-
Ultrasound Guided Bilateral Superficial Cervical Block for Post-operative Pain Therapy in Thyroid Surgery
NCT03109691 ·Status: UNKNOWN ·Phase: NA
-
Bilateral Cervical Plexus Block for Postoperative Pain After Thyroidectomy
NCT07496970 ·Status: COMPLETED ·Phase: NA
-
Ultrasound Guided Intermediate Cervical Plexus Block in Thyroid Surgery
NCT03731468 ·Status: COMPLETED ·Phase: NA
-
The Perioperative Analgesic Efficiency of Bilateral Superficial Cervical Plexus Block in Patients With Thyroidectomy
NCT02680353 ·Status: COMPLETED ·Phase: NA
-
Ultrasound Guided Bilateral Superficial Cervical Plexus Block in Patients Undergoing Total Thyroidectomy.
NCT04993521 ·Status: COMPLETED ·Phase: NA
-
Safety and Efficacy of Bilateral Superficial Cervical Plexus Block in Thyroidectomy
NCT01454609 ·Status: COMPLETED ·Phase: PHASE2
-
Ropivacaine Plus Magnesium Sulphate Infiltration
NCT05294393 ·Status: COMPLETED ·Phase: PHASE4
-
Methods of Post Operative Analgesia in Patients Undergoing Thyroidectomy
NCT07045870 ·Status: RECRUITING ·Phase: NA
-
Pain Medications Following Thyroidectomy and Parathyroidectomy
NCT03640247 ·Status: COMPLETED ·Phase: PHASE1
-
Tizanidine and Superficial Cervical Block on Pain After Thyroidectomy
NCT02725359 ·Status: COMPLETED ·Phase: PHASE4
-
Postoperative Analgesia and Recovery Quality in Total Thyroidectomy
NCT07547124 ·Status: NOT_YET_RECRUITING
-
The Effect of Bilateral Intermediate Cervical Plexus Block on the Surgical Stress Response Following Total Thyroidectomy
NCT07740460 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
The Efficacy of Intermediate Cervical Plexus Block Versus Cutaneous and Thyroid Capsular Blocks
NCT03269890 ·Status: COMPLETED ·Phase: NA
-
Intermediate Cervical Block Under Ultrasound for Thyroid Surgery: Impact on Per and Postoperative Opioid Consumption
NCT03107585 ·Status: COMPLETED ·Phase: NA
-
Dexmedetomidine Versus Dexamethasone as Adjuvants to Bupivacaine for Intermediate Cervical Plexus Block
NCT05793060 ·Status: RECRUITING ·Phase: PHASE4
-
Effect of Propofol on Remifentanil-induced Postoperative Hyperalgesia in Patients Undergoing Thyroid Surgery
NCT01189721 ·Status: UNKNOWN ·Phase: PHASE4
-
Bilateral Superficial Cervical Plexus Block in Thyroid/Parathyroid Surgery
NCT04051099 ·Status: UNKNOWN ·Phase: NA
-
Efficacy of I/v Nalbuphine v/s Iv Lignocain in Attanuation of Pressor Responseduring Laryngeoscopy and Intubation in Middle Age Patient Planned for Thyroid Surgery
NCT05298761 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1
-
The Effect of Intravenous Lidocaine on Pain After Thyroidectomy
NCT01608360 ·Status: UNKNOWN ·Phase: PHASE4
-
Superficial Cervical Plexus Block With Dexmedetomidine Versus Without Adjuvant in Thyroid Surgery
NCT07274670 ·Status: COMPLETED ·Phase: NA
-
Effect of Higher Doses of Remifentanil on Postoperative Pain in Patients Undergoing Thyroidectomy
NCT01761149 ·Status: UNKNOWN ·Phase: PHASE4
-
Efficacy of Ropivacaine (With Epinephrine) in BABA Endoscopic and Robotic Thyroidectomy
NCT02112370 ·Status: COMPLETED ·Phase: PHASE3
-
Peri Tonsillar Infiltration of Ketamine or Bupivacaine for Post Tonsillectomy Analgesia
NCT05341323 ·Status: COMPLETED ·Phase: PHASE4
-
EFFECTS OF TWO ANESTHESİA TECHNİQUES ON INFLAMMATORY RESPONSE AND AMİNO ACİD METABOLİSM İN THYROİD SURGERY
NCT07592832 ·Status: NOT_YET_RECRUITING ·Phase: NA