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EFFECTS OF TWO ANESTHESİA TECHNİQUES ON INFLAMMATORY RESPONSE AND AMİNO ACİD METABOLİSM İN THYROİD SURGERY

NCT07592832 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2026-05-18

No results posted yet for this study

Summary

The main aim of this study is to compare the effects of two different anesthesia methods-(1) general anesthesia alone and (2) combination of general anesthesia with cervical plexus block-on postoperative inflammatory process and amino acid metabolism in patients undergoing thyroidectomy.

Conditions

  • General Anesthesia
  • Cervical Plexus Block
  • Thyroid Surgery

Interventions

PROCEDURE

General Anesthesia

In our study, one patient group will receive only general anesthesia, while the other group will receive general anesthesia in addition to ultrasound-guided cervical plexus block. The inflammatory response is a natural response of the body's immune system to surgical trauma, and it can vary depending on the anesthetic agent used. In regulating this response, molecules such as IL-1β, TNF-α, IL-6, IL-10, and IL-40 are important indicators that determine the severity and duration of inflammation. These parameters will be examined and compared in both groups.

PROCEDURE

cervical plexus block

In our study, one patient group will receive only general anesthesia, while the other group will receive general anesthesia in addition to ultrasound-guided cervical plexus block.

Sponsors & Collaborators

  • Harran University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-07-30
Primary Completion
2027-02-20
Completion
2027-02-20

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07592832 on ClinicalTrials.gov