Wearable-Supported Prehabilitation and Rehabilitation for Patients Undergoing Surgery for Pancreatic Cancer

Summary

The goal of this clinical trial is to evaluate whether a wearable-enabled prehabilitation and rehabilitation pathway can improve recovery and post-operative outcomes in adults undergoing surgery for pancreatic cancer or related pancreatic/periampullary conditions.

The main questions it aims to answer are:

Does a wearable-enabled prehabilitation and rehabilitation programme reduce post-operative complications within 30 and 90 days after surgery? Is the use of wearable devices and remote monitoring feasible, acceptable, and useful for patients and healthcare professionals during the perioperative pathway?

Researchers will compare patients receiving the wearable-enabled pathway with a matched historical control group who received standard care to determine whether the intervention is associated with improved surgical and recovery outcomes.

Participants will:

Provide informed consent and complete baseline assessments and questionnaires. Take part in the Greater Manchester Prehab4Cancer programme before surgery, including personalised exercise, nutritional support, and wellbeing support.

Wear a Corsano CardioWatch device to continuously monitor physiological and activity data.

Use home monitoring equipment, including weight scales and blood pressure monitoring devices.

Complete questionnaires and participant logs during prehabilitation and recovery.

Receive regular support from the research team during participation. Undergo pancreatic surgery and receive standard NHS perioperative care. Continue wearable monitoring and rehabilitation after hospital discharge. Be followed for up to 12 months after surgery using routine clinical data to assess recovery, complications, hospital utilisation, and survival.

Optionally participate in a focus group to discuss their experiences of wearable-enabled care.

Conditions

• Pancreatic Cancer
• Pancreatic Neoplasms
• Periampullary Carcinoma
• Pancreatic Surgery
• Perioperative Care

Interventions

DEVICE

Corsano CardioWatch

A wearable monitoring device used throughout the perioperative pathway to collect continuous physiological and activity data, including measures such as physical activity, heart rate, respiratory rate, oxygen saturation, skin temperature, and sleep-related metrics.

BEHAVIORAL

Prehab4Cancer Programme

A personalised prehabilitation and rehabilitation programme comprising exercise, nutritional support, and wellbeing support delivered before and after pancreatic surgery.

Sponsors & Collaborators

• Medtronic

  collaborator INDUSTRY

• Manchester University NHS Foundation Trust

  lead OTHER_GOV

Principal Investigators

• Lukas Hughes-Noehrer, PhD · Manchester University NHS Foundation Trust

Study Design

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2026-10-01

Primary Completion

2028-03-31

Completion

2028-09-30