PancFit: Multimodal Exercise During Preoperative Therapy for Pancreatic Cancer

Summary

Any time the words "you," "your," "I," or "me" appear, it is meant to apply to the potential participant.

The goal of this clinical research study is to learn if regular exercise and behavioral skills training can help to improve physical activity in patients with pancreatic cancer who are scheduled to receive chemotherapy and/or radiation before standard-of-care surgery.

This is an investigational study.

Up to 128 participants will be enrolled on this study. All will take part at MD Anderson.

Conditions

• Other Disorders of Glucose Regulation and Pancreatic Internal Secretion
• Pancreatic Cancer

Interventions

BEHAVIORAL

Aerobic Exercise and Strength Training Exercises

Participants complete up to 30 minutes of moderate-intensity aerobic exercise (such as brisk walking, stationary cycling, and/or elliptical or stair stepping machines) for at least 5 days each week. Participants complete strength training exercises at least 2 times per week.

BEHAVIORAL

Questionnaires

Participants complete 4 questionnaires about physical abilities, motivation, and quality of life They should take about 25 minutes total to complete.

BEHAVIORAL

Nutritional Questionnaire and Nutritional Counseling

Participants complete a nutritional questionnaire and receive nutritional counseling. It should take about 5 minutes to complete. Participants receive educational materials and personalized counseling based on participant's answers.

OTHER

Booklet

Participants receive a booklet that contains a stretching guide with full-body stretches and safety.

BEHAVIORAL

Phone Calls

Participants contacted by phone by member of study staff one (1) time each week for the first 4 weeks, and then every 2 weeks after that for behavioral skills training and to see how participant is doing. These calls should last about 15 minutes.

BEHAVIORAL

Physical Assessments

After completion of chemotherapy and/or radiation, 3-6 weeks after surgery, and then 3-7 months after surgery: Participant's hand grip strength measured using a hand-held machine. Participants arm strength measured using an arm curl test. Participants asked to rise from a chair without using their arms to push off. Participants complete a 6-minute walk test to see how far participant can walk in 6 minutes.

Sponsors & Collaborators

• M.D. Anderson Cancer Center

  lead OTHER

Principal Investigators

• Matthew H. Katz, MD · M.D. Anderson Cancer Center

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2017-06-13

Primary Completion

2022-12-31

Completion

2026-12-31

Countries

• United States

Study Locations