Multimodal Prehabilitation for Tumor-Related Bowel Obstruction

Summary

The goal of this clinical trial is to establish a multimodal prehabilitation protocol suitable for patients with tumor-related bowel obstruction during the perioperative period, and to explore its safety and efficacy; to evaluate the impact of this protocol on short-term and long-term clinical outcomes and recovery indicators.The participants will be divided into two groups. The experimental group will receive an integrated program of preoperative multi-modal pre-rehabilitation intervention combined with postoperative immune nutrition support; the control group will receive traditional perioperative management for intestinal obstruction.

Conditions

• Malignant Tumor
• Prehabilitation

Interventions

BEHAVIORAL

Multimodal prehabilitation program

Multimodal prehabilitation program adopts a planned, structured, repeatable, and purposeful approach, encompassing exercise, nutrition, and psychological factors.

BEHAVIORAL

Standard six-step treatment

The standard six-step treatment protocol refers to: decompression, nutritional supplementation, suppression of digestive fluid secretion, hormone therapy, diuresis, exercise, and promotion of intestinal peristalsis.

BEHAVIORAL

ERAS protocol

The core content is to adopt a series of optimized measures performed during the perioperative period on the basis of evidence-based medical findings to reduce the physiological and psychological stress of patients and to accelerate their recovery.

Sponsors & Collaborators

• Yantai Yuhuangding Hospital

  collaborator OTHER

• Rizhao People's Hospital

  collaborator OTHER

• Weifang People's Hospital

  collaborator OTHER

• The Second Hospital of Shandong University

  collaborator OTHER

• Fujian Medical University Union Hospital

  collaborator OTHER

• Fudan University

  collaborator OTHER

• Xinjiang Medical University

  collaborator OTHER

• Peking University People's Hospital

  collaborator OTHER

• The First School of Clinical Medicine of Binzhou Medical University

  collaborator UNKNOWN

• Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

  collaborator OTHER

• The Affiliated Hospital of Qingdao University

  lead OTHER

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

85 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2026-08-01

Primary Completion

2028-07-01

Completion

2028-08-01

Countries

• China

Study Locations