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Eye Movement Intervention With Different Memory Reactivation Procedures for Intrusive Traumatic Memories

NCT07767396 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 117

Last updated 2026-08-17

No results posted yet for this study

Summary

Post-Traumatic Stress Disorder (PTSD) and trauma-related symptoms are often characterized by recurrent intrusive memories that cause distress and interfere with daily functioning. Although trauma-focused interventions such as Eye Movement Desensitization and Reprocessing (EMDR) may be effective, they often involve engagement with trauma-related memories, which can be distressing for some individuals and may affect treatment acceptability. This randomized controlled trial will evaluate a standardized eye-movement-based procedure for trauma-exposed individuals experiencing recurrent intrusive memories. Participants will be randomly assigned to one of several memory-related task conditions involving eye movements. The study will assess the frequency and distress of trauma-related intrusive memories at prespecified assessment points, as well as PTSD symptoms, intervention-related distress, acceptability, and safety. Findings from this trial may help inform the development of tolerable approaches for targeting trauma-related intrusive memories.

Conditions

  • Post-traumatic Stress Disorder (PTSD)
  • Intrusive Memories of Traumatic Event(s)

Interventions

BEHAVIORAL

Unconscious Trauma Reactivation plus Eye Movements

Participants will complete a procedure involving unconscious activation combined with eye movements.

BEHAVIORAL

Active Trauma Memory Reactivation plus Eye Movements

Participants will complete a standardized procedure involving recall of a trauma-related memory combined with eye movements.

BEHAVIORAL

Neutral Memory Reactivation plus Eye Movements

Participants will complete a standardized procedure involving recall of a neutral memory combined with eye movements.

Sponsors & Collaborators

  • Shaanxi Normal University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-08-15
Primary Completion
2028-09-15
Completion
2028-12-15

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07767396 on ClinicalTrials.gov