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Perioperative HALP and Surgical Outcomes

NCT07761975 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 131

Last updated 2026-08-13

No results posted yet for this study

Summary

Esophagectomy is associated with substantial postoperative morbidity despite advances in perioperative care. The Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) score has been proposed as a composite biomarker reflecting nutritional, inflammatory, and immune status; however, its perioperative behavior and clinical significance after esophagectomy remain unclear. This retrospective cohort study evaluates perioperative changes in HALP and examines the associations of preoperative, postoperative day 1, and postoperative day 7 HALP measurements with postoperative complications, including overall and major complications, anastomotic leakage, ICU readmission, and length of hospital stay. The study aims to clarify the potential role of perioperative HALP as a marker of postoperative recovery and adverse clinical outcomes following esophagectomy.

Conditions

  • Esophagectomy
  • HALP Score
  • Perioperative Biomarkers
  • Postoperative Complications
  • Perioperative Risk Assessment

Interventions

OTHER

Perioperative HALP Score Assessment

Assessment of the Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) score using routinely collected laboratory measurements obtained preoperatively and on postoperative days 1 and 7. No intervention or treatment was assigned as part of the study.

Sponsors & Collaborators

  • Istanbul Saglik Bilimleri University

    lead OTHER

Principal Investigators

  • Hürü Ceren Gökduman, MD · Basaksehir Cam ve Sakura State Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-06-10
Primary Completion
2026-07-15
Completion
2026-07-22

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07761975 on ClinicalTrials.gov