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Kinetics and Prognostic Value of NeuroFilament Light in Post-cardiac Arrest: A Prospective Multicenter Study

NCT07760636 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 270

Last updated 2026-08-12

No results posted yet for this study

Summary

The purpose of this study is to assess the prognostic value of absolute value and kinetic of neurofilament light chain (NFL) collected at different time points (at admission, 12h, 24h, 48h, 72h, 96h, and day 7 after ICU admission) in predicting poor and good neurological outcome in comatose patients after cardiac arrest.

Conditions

  • Cardiac Arrest (CA)
  • Intensive Care Unit (ICU) Admission
  • Return of Spontaneous Circulation
  • Comatose

Interventions

OTHER

Value of neurofilament light chain (NFL) at different time points

Value of neurofilament light chain (NFL) at different time points (H0, H12, H24, H48, H72, H96, and day 7 after ICU admission

Sponsors & Collaborators

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Principal Investigators

  • Sarah Benghanem · Medical ICU, Cochin hospital, Paris

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-09-30
Primary Completion
2028-06-30
Completion
2028-06-30

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07760636 on ClinicalTrials.gov