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Effect of Tranexamic Acid on Bleeding After Bariatric Surgery

NCT07754396 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 140

Last updated 2026-08-10

No results posted yet for this study

Summary

Postoperative bleeding is an important complication of bariatric surgery and may lead to increased morbidity, prolonged hospitalization, and higher healthcare costs. Tranexamic acid (TXA) has been shown to reduce perioperative blood loss in several surgical specialties; however, evidence regarding its effectiveness and safety in bariatric surgery remains limited.

This retrospective observational cohort study aims to evaluate the effect of prophylactic intraoperative tranexamic acid administration on perioperative bleeding in patients undergoing bariatric surgery. The primary objective is to assess the postoperative decrease in hemoglobin levels. Secondary objectives include evaluating the need for blood transfusion, length of hospital stay, and the incidence of thromboembolic complications, including deep vein thrombosis, pulmonary embolism, portal vein thrombosis, and acute coronary syndrome.

The study includes patients who underwent bariatric surgery at G. Gennimatas General Hospital between May 1, 2024, and April 30, 2026.

Conditions

  • Morbid Obesity
  • Perioperative Hemorrhage
  • Obesity
  • Tranexamic Acid
  • Postoperative Hemorrhage

Sponsors & Collaborators

  • G.Gennimatas General Hospital

    lead OTHER

Principal Investigators

  • Amalia Douma, PHD · General Hospital of Athens

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-05-01
Primary Completion
2026-04-30
Completion
2026-04-30

Countries

  • Greece

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07754396 on ClinicalTrials.gov