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Shorter Treatment Regimen Implementation Evaluation Study

NCT07747792 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 175

Last updated 2026-08-05

No results posted yet for this study

Summary

"Evaluation of the implementation of the shorter treatment regimen for children and adolescents with non-severe TB in Zambia" is a parallel and convergent mixed methods evaluation study of implementation and clinical outcomes of STR in real-world settings. The study enrolled caregivers and children who were recepients of care on STR, health workers providing STR services, facilities leadership and policy makers.

This study aimed to explore acceptability, fidelity, and feasibility of implementing STR in real-world settings in order to optimize program implementation. Additionally, the study aimed to determine the clinical outcomes of patients initiated on the STR in order to ascertain the performance of the regimen in a programmatic setting and contribute to the evidence base for using STR in clinical practice.

Conditions

  • Tuberculosis (TB)
  • Tuberculosis in Children
  • Tuberculosis Treatment Effectiveness
  • Tuberculosis Active

Sponsors & Collaborators

  • Centre for Infectious Disease Research in Zambia

    lead OTHER

Principal Investigators

  • Monde Muyoyeta, MBChB PhD · Centre for Infectious Disease Research in Zambia

Eligibility

Min Age
3 Months
Max Age
14 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-03-01
Primary Completion
2026-01-30
Completion
2026-01-30

Countries

  • Zambia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07747792 on ClinicalTrials.gov