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Phase I Study of Carbon-Ion Lattice Radiotherapy for Large Thoracic Tumors

NCT07744074 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2026-08-04

No results posted yet for this study

Summary

This is the first prospective clinical study to evaluate the efficacy and safety of induction chemoimmunotherapy followed by carbon ion radiotherapy and consolidation immunotherapy in patients with unresectable locally advanced non-small cell lung cancer (NSCLC). Based on this prospective study, tumor tissue, blood, urine, and stool samples from participants will be collected and analyzed to identify predictive markers of treatment response.

Conditions

  • Carbon Ion Radiotheray

Interventions

RADIATION

Carbon ion - Lattice radioIon Lattice Radiation Therapy for Thoracic bulky solid tumors

Carbon ion - Lattice radioIon Lattice Radiation Therapy for Thoracic bulky solid tumors

Sponsors & Collaborators

  • Ji Yongling

    lead OTHER

Principal Investigators

  • Yongling Ji, MD · Zhejiang Cancer Hospital, Hangzhou, Zhejiang 310022

Study Design

Allocation
NA
Purpose
OTHER
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-05-26
Primary Completion
2028-12-31
Completion
2028-12-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07744074 on ClinicalTrials.gov