Local Therapy in Advanced NSCLC With Non-progressive Disease (PD) After First Line Therapy
NCT03046316 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2020-07-23
Summary
This is a prospective single arme real-world study clinical study, which aims to investigate the overall benefit and safety of consolidative therapy in advanced NSCLC (stage III/IV) patients , who do not progress after front line systemic therapy (chemotherapy, target therapy or immunological checkpoint inhibitors).
Conditions
- Lung Neoplasms
Interventions
- OTHER
-
local consolidative treatment
local consolidative treatment to primary or metastases, which includes surgery, radiotherapy or interventional therapy
Sponsors & Collaborators
-
Guangdong Association of Clinical Trials
lead OTHER
Principal Investigators
-
Zhen Wang, PhD,MD · Guangdong General Hospital&Guangdong Academy of Medical Sciences
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-06-01
- Primary Completion
- 2022-07-01
- Completion
- 2026-07-01
Countries
- China
Study Locations
More Related Trials
-
A Study of Concurrent Chemoradiation With Atezolizumab in Participants With Untreated Extensive-Stage (ES) Small Cell Lung Cancer (SCLC)
NCT04636762 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Tolerability of Low Dose Radiotherapy Concurrent SBRT and PD-1 Inhibitors in Advanced NSCLC.
NCT05615142 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Sequential Chemo-immunotherapy Plus Thoracic Radiotherapy for Elderly And/or Frail Stage III Non-small-cell Lung Cancer
NCT05557552 ·Status: RECRUITING ·Phase: NA
-
Phase II Trial of Consolidative Thoracic Radiotherapy for ES-SCLC After Standard Care of Chemo-immunotherapy
NCT05552846 ·Status: RECRUITING ·Phase: NA
-
Hypofractionated Radiotherapy Followed by Hypo-boost for Local Advanced NSCLC
NCT03900117 ·Status: COMPLETED ·Phase: PHASE2
-
Local Non-salvage Radiotherapy for Synchronous Oligometastatic Non-small-cell Lung Cancer.
NCT03119519 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study Evaluating Neoadjuvant Chemotherapy, Concurrent Chemoradiotherapy Combined With Dual Immune Checkpoint Blockade in Patients With Locally Advanced Non-Small Cell Lung Cancer
NCT07103395 ·Status: RECRUITING ·Phase: PHASE2
-
Methylprednisolone After Split-course Chemoradiotherapy For Bulky Local Advanced None-small Cell Lung Cancer
NCT03661567 ·Status: TERMINATED ·Phase: PHASE2
-
First-line Treatment for ES-SCLC with Chemotherapy Combined with PD-1/PD-L1 Inhibitor Sequential Thoracic Radiotherapy
NCT06586697 ·Status: RECRUITING ·Phase: PHASE2
-
Evaluating Efficacy and Safety of Anlotinib Combined With Concurrent Chemoradiotherapy Followed by Consolidation Immunotherapy for Locally Advanced Non-small Cell Lung Cancer
NCT05481775 ·Status: WITHDRAWN ·Phase: PHASE2
-
Induction Chemotherapy and Toripalimab Followed by Chemoradiotherapy for Large-volume Local Advanced NSCLC
NCT05888402 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Pre-operative Chemotherapy Versus Concurrent Chemoradiotherapy in Locally Advanced Non-small Cell Lung Cancer
NCT01054482 ·Status: UNKNOWN ·Phase: PHASE2
-
Radiotherapy Combined With ICIs as Treatment for LA-NSCLC After Failing Induction Immunochemotherapy
NCT06031597 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
Standard-of-care Systemic Therapy With or Without Local Therapy in Patients With Oligoprogressive Non-Small Cell Lung Cancer(NSCLC)
NCT07076693 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2/PHASE3
-
Phase 1b/2 Study of LDRT in Combination With AK104 Plus Chemotherapy as First-line Treatment for ES-SCLC
NCT06477523 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Maintenance Targeted Therapy With or Without Stereotactic Body Radiation Therapy for Stage IV Non-small Cell Lung Cancer
NCT03595644 ·Status: COMPLETED ·Phase: PHASE2
-
An Observational Clinical Study of Stereotactic Radiotherapy for Advanced Non-Small Cell Lung Cancer With Stable Disease After PD-1 Inhibitor Treatment
NCT05486650 ·Status: RECRUITING
-
Study of Split-course Chemoradiotherapy For Postoperative Locoregional Recurrence Of Non-small Cell Lung Cancer
NCT03006575 ·Status: UNKNOWN ·Phase: PHASE2
-
Clinical Randomized Study of Concurrent Chemo-radiotherapy vs Radiotherapy Alone to Local-advanced Small Cell Lung Cancer (SCLC)
NCT01745445 ·Status: UNKNOWN ·Phase: PHASE2
-
Neoantigen-based Peptide Vaccine, PD-1 Inhibitor, and Radiotherapy for Advanced NSCLC Progressed After First-line Treatment
NCT06752044 ·Status: RECRUITING ·Phase: NA
-
A Study of Envafolimab in Subjects With Stage III Non-Small Cell Lung Cancer
NCT05414630 ·Status: UNKNOWN ·Phase: PHASE2
-
Accelerated Hypofractionated vs. Conventionally Fractionated Concurrent CRT for LS-SCLC
NCT02990780 ·Status: UNKNOWN ·Phase: PHASE3
-
Aggressive Thoracic Radiotherapy for Stage Ⅳ Non Small Cell Lung Cancer
NCT03565120 ·Status: UNKNOWN ·Phase: NA
-
Randomized Controlled Clinical Study of Drug Therapy Combined With Thoracic Radiotherapy for Non-oligometastatic NSCLC
NCT05176067 ·Status: UNKNOWN ·Phase: NA
-
Spatial Fragmentation Combined With Low-dose Radiotherapy for Immunotherapy Combined With Chemotherapy-resistant Locally Advanced or Advanced Non-small Cell Lung Cancer
NCT06775678 ·Status: RECRUITING ·Phase: PHASE2