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Can Pretreatment With Analgesics Reduce Postendodontic Pain?

NCT07271654 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 160

Last updated 2025-12-09

No results posted yet for this study

Summary

This randomized controlled trial investigated whether a single dose of diclofenac sodium taken before a root canal procedure can reduce pain in the hours following the treatment. 160 patients with tooth pain from irreversible pulpitis were divided into two groups. One group received 100mg of diclofenac sodium 30 minutes before their procedure, while the other group received no pretreatment. Pain levels were measured at 6, 12, and 24 hours after the procedure. The study found that patients who took diclofenac before treatment were significantly more likely to be pain-free at 6 and 12 hours after the procedure compared to those who did not.

Conditions

  • Pulpitis - Irreversible

Interventions

PROCEDURE

Pre treatment with NSAIDS

Single oral dose of 100 mg Diclofenac Sodium, administered 30 minutes prior to endodontic treatment.

PROCEDURE

No pretreatment with NSAIDS.

Single oral dose of 100 mg Diclofenac Sodium, administered 30 minutes prior to endodontic treatment.

Sponsors & Collaborators

  • College of Physicians and Surgeons Pakistan

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-08-01
Primary Completion
2025-10-01
Completion
2025-10-01

Countries

  • Pakistan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07271654 on ClinicalTrials.gov