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Lactic Acid Bacteria for Reducing Blue Light-Induced Eye Fatigue

NCT07737938 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 150

Last updated 2026-07-30

No results posted yet for this study

Summary

With the widespread use of digital devices and prolonged screen exposure, digital eye strain (DES), also known as computer vision syndrome, has become a global public health concern. Emerging evidence suggests that the gut-eye axis may play an important role in ocular health, as gut microbiota imbalance is associated with systemic inflammation and oxidative stress. Specific probiotics may help alleviate eye discomfort through modulation of immune responses and enhancement of antioxidant defense mechanisms. This randomized, double-blind, placebo-controlled study aims to evaluate the efficacy of supplementation with specific probiotics, Bifidobacterium longum BL531 and Lactobacillus reuteri LR1349, in improving digital eye strain symptoms in adults.

Conditions

  • Digital Eye Strain (DES)

Interventions

DIETARY_SUPPLEMENT

Placebo

Maltodextrin

DIETARY_SUPPLEMENT

BL531_low dose

1×10\^10 cfu/day

DIETARY_SUPPLEMENT

BL531_high dose

2.5×10\^10 cfu/day

DIETARY_SUPPLEMENT

LR1349_low dose

1×10\^10 cfu/day

DIETARY_SUPPLEMENT

LR1349_high dose

2.5×10\^10 cfu/day

Sponsors & Collaborators

  • Synbio Tech Inc.

    lead INDUSTRY

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-09-01
Primary Completion
2027-08-31
Completion
2027-12-31

Countries

  • Taiwan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07737938 on ClinicalTrials.gov