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Effects of Respiratory Muscle Training on Tongue Corticomotor Excitability

NCT07737015 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2026-07-30

No results posted yet for this study

Summary

The tongue plays a central role in essential oral functions, including swallowing, speech, and upper airway control. Its coordinated interaction with the respiratory system is particularly relevant in clinical conditions such as obstructive sleep apnea and dysphagia. While respiratory muscle training is increasingly used in these contexts, its effects on the neural control of tongue function remain poorly understood.

This randomized cross-over pilot study aimed to investigate the acute effects of inspiratory (IMT) and expiratory (EMT) muscle training on tongue corticomotor excitability using transcranial magnetic stimulation. These results will provide novel insight into the neurophysiological mechanisms linking respiratory interventions and oral motor control.

Conditions

  • Healthy Adult Participants

Interventions

DEVICE

EMT

An expiratory threshold loading device set at 50% of the baseline maximal expiratory pressure (PEmax) was used. The training session consisted of five cycles of 20 breaths performed against the device, with a 2-minute rest period between cycles. Each breath consisted of quiet inhalation through the device, followed by a deep and forceful expiration against the set load.

DEVICE

IMT

An inspiratory threshold loading device set at 50% of the baseline maximal inspiratory pressure (PImax) was used. The training session consisted of five cycles of 20 breaths performed against the device, with a 2-minute rest period between cycles. Each breath consisted of quiet exhalation through the device, followed by a deep and forceful inspiration against the prescribed load.

Sponsors & Collaborators

  • Université Catholique de Louvain

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-10-01
Primary Completion
2024-12-06
Completion
2024-12-06

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07737015 on ClinicalTrials.gov