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Adequacy of Haemodiafiltration: Middle Molecules Clearance, Patients Reported Outcomes and Sodium Balance

NCT07717255 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 300

Last updated 2026-07-21

No results posted yet for this study

Summary

The goal of this observational study is to understand the differences in terms of middle molecules clearance and patient outcomes in High (\>23Litres (L)) vs Low (\<23 L) convection volume (CV) Hemodiafiltration (HDF) and to understand the effect of dialysate fluid sodium concentration (137 vs 140 mmol/L) on overhydration volume in patients on HD and HDF.

Conditions

  • Haemodiafiltration
  • Haemodialysis
  • Patient Reported Outcome Measurements
  • Nutrition
  • Malnutrition (Calorie)
  • Fluid Balance Outcomes

Sponsors & Collaborators

  • East and North Hertfordshire NHS Trust

    lead OTHER_GOV

Principal Investigators

  • Usama Afzal Butt, MBBS, MRCP · East and North Hertfordshire NHS Trust

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-01-09
Primary Completion
2030-11-01
Completion
2030-11-01

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07717255 on ClinicalTrials.gov