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Puff Topography and Sensory Effects Across IQOS Device Generations

NCT07712887 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2026-07-30

No results posted yet for this study

Summary

The goal of this clinical trial is to learn how people use two generations of IQOS heated tobacco devices and how each device affects their smoking behavior and sensory experience.

The main questions it aims to answer are:

* Do participants puff differently when using the newer IQOS Iluma i compared to the older IQOS 2.4?
* Does the flavor of the tobacco stick (preferred flavor vs. standard tobacco flavor) affect puffing behavior or sensory experience?
* What are the differences in throat hit, mouthfeel, and satisfaction between the two devices?

Participants will:

* Attend 2 laboratory visits at the American University of Beirut
* Use both the IQOS Iluma i and IQOS 2.4 devices during each visit
* Have their puffing behavior recorded automatically during device use
* Provide a breath sample before and after each use session
* Complete short questionnaires about how each device felt and their urge to smoke

Conditions

  • Nicotine Dependence
  • Tobacco Use

Interventions

DEVICE

IQOS Iluma i with TEREA Tobacco Sticks

The IQOS Iluma i is an induction-heated tobacco device used with TEREA STICKS. Participants use the device ad libitum during two smoking bouts (preferred flavor and Amber flavor conditions) across two study visits. Puff topography is recorded continuously during use.

DEVICE

IQOS 2.4 with HEETS Tobacco Sticks

The IQOS 2.4 is a ceramic blade-heated tobacco device used with HEETS tobacco sticks. Participants use the device ad libitum during two smoking bouts (preferred flavor and Amber flavor conditions) across two study visits. Puff topography is recorded continuously during use.

Sponsors & Collaborators

  • American University of Beirut Medical Center

    lead OTHER

Principal Investigators

  • Soha Talih · American University of Beirut Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-07-27
Primary Completion
2027-10-01
Completion
2027-12-15

Countries

  • Lebanon

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07712887 on ClinicalTrials.gov