Study to Characterize Mismatched to Fully HLA-Matched Ossium HPC, Marrow and Living Donor Transplantation in Patients With Hematologic Malignancies
NCT07710781 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 300
Last updated 2026-07-20
Summary
Prospective, multi-center open label study of HLA-partially to fully matched allogeneic cryopreserved deceased donor bone marrow transplantation and living donor transplantation for patients with hematologic malignancies.
Conditions
- Hematologic Malignancy
- Acute Leukemia
- Acute Lymphoblastic Leukemia
- Acute Myeloid Leukemia
- Acute Biphenotypic Leukemia
- Acute Undifferentiated Leukemia
- CLL (Chronic Lymphocytic Leukemia)
- Chronic Myeloid Leukemia
- MDS (Myelodysplastic Syndrome)
- Non Hodgkin Lymphoma
- Hodgkin Lymphoma
- Cutaneous T Cell Lymphomas (CTCL)
Interventions
- OTHER
-
Standard of care living donor - Mismatched Unrelated
Mismatched Unrelated PBSC donor
- OTHER
-
Ossium HPC, Marrow
Cryopreserved deceased donor bone marrow
- OTHER
-
Standard of care living donor - Haplo Related
Haplo Related PBSC donor
Sponsors & Collaborators
-
Ossium Health, Inc.
lead INDUSTRY
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 12 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-12-01
- Primary Completion
- 2029-03-31
- Completion
- 2031-03-31
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